Tanya Stoyanova

Assistant Professor of Radiology (Cancer Early Detection-Canary Center)

Academic Appointments

Assistant Professor, Radiology
Member, Bio-X
Member, Maternal & Child Health Research Institute (MCHRI)
Member, Stanford Cancer Institute

Honors & Awards

NCI R37 MERIT Award, National Cancer Institute (2020-2025)
Society for Basic Urologic Research (SBUR) Young Investigator Award, Society for Basic Urologic Research (2020)
Idea Development Award, U.S. Department of Defense, Prostate Cancer Research Program (2018-2021)
McCormick and Gabilan Faculty Award, Stanford University (2016-2018)
K99/R00 Pathway to Independence Award, National Institutes of Health/National Cancer Institute (2014-2019)
2014 Stewart Rahr Prostate Cancer Foundation Young Investigator Award, Prostate Cancer Foundation (2014-2017)
2014 Department of Pharmacology Retreat Award, University of California, Los Angeles, CA (2014)
Chancellor's Award for Postdoctoral Research, University of California, Los Angeles, CA (2014)
Postdoctoral Fellowship. Prostate Cancer Research Program, U.S. Department of Defense (2012-2014)
Postdoctoral Fellowship, California Institute for Regenerative Medicine (2010-2012)
SIGMA Xi Student Research Forum Award for Graduate and Professional Students 2008, University of Illinois, Chicago, IL (2008)
SIGMA Xi Student Research Forum Award for Graduate and Professional Students 2007, University of Illinois, Chicago, IL (2007)
Sally Frost Mason Outstanding Woman Student in Biological Sciences 2003, University of Kansas, Lawrence, KS (2003)
Sally K. Frost Mason and Kenneth A. Mason Outstanding Senior 2003. Division of Biological Sciences, University of Kansas, Lawrence, KS (2003)
Ruben Zadigan Environmental Studies Scholarship, University of Kansas, Lawrence, KS (2001-2003)

Professional Education

Postdoctoral Fellowships, University of California, Los Angeles, CA, USA, Stem cell and Cancer Biology (2015)
PhD, University of Illinois, Chicago, IL, USA, Biochemistry and Molecular Genetics (2009)
BS, University of Kansas, Lawrence, KS, USA, Genetics (2003)
BS, Technical University of Varna, Varna, Bulgaria, Ecology and Protection of the Environment (2002)

Patents

Meghan A. Rice, Vineet Kumar, Dhanir Tailor , Sanjay V. Malhotra and Tanya Stoyanova. "United States Patent 17/307,699 Methoxychalcone Derivative and Uses Thereof", Leland Stanford Junior University

Current Research and Scholarly Interests

Stoyanova lab develops new early cancer detection methods and therapeutic strategies for late stage cancers. The current research focus is on protein-based biomarkers for early cancer detection as well as development of new small molecule inhibitors and antibody-based therapies for prostate and other epithelial cancers. The ultimate goals of the laboratory are to improve the early diagnosis and prognosis of clinically significant cancers and guide the development of novel and effective therapeutic strategies for metastatic prostate and other epithelial cancers.

All Publications

Profiles With Related Publications

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James D. Brooks

Keith and Jan Hurlbut Professor
Clinical Focus
Cancer > Urologic Oncology, Prostate cancer screening, Prostate cancer - localized, Prostate cancer active surveillance, Urology
Research Interests
We use genomic approaches to identify disease biomarkers. We are most interested in translating biomarkers into clinical practice in urological diseases with a particular focus in cancer.

330 Total Publications
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Anne Brunet

Michele and Timothy Barakett Endowed Professor
Research Interests
Our lab studies the molecular basis of longevity. We are interested in the mechanism of action of known longevity genes, including FOXO and SIRT, in the mammalian nervous system. We are particularly interested in the role of these longevity genes in neural stem cells. We are also discovering novel genes and processes involved in aging using two short-lived model systems, the invertebrate C. elegans and an extremely short-lived vertebrate, the African killifish N. furzeri.

137 Total Publications
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Sophia Chernikova

Sr Res Scientist-Basic Ls, Neurosurgery

19 Total Publications
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Gilbert Chu

Professor of Medicine (Oncology) and of Biochemistry
Clinical Focus
Cancer > GI Oncology, Oncology
Research Interests
After shuttering the wet lab, we have focused on: a point-of-care device to measure blood ammonia and prevent brain damage; a human protein complex that juxtaposes and joins DNA ends for repair and V(D)J recombination; and strategies for teaching students and for reducing selection bias in educational programs.

74 Total Publications
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Karlene Cimprich

Professor of Chemical and Systems Biology and, by courtesy, of Biochemistry
Research Interests
Genomic instability contributes to many diseases, but it also underlies many natural processes. The Cimprich lab is focused on understanding how mammalian cells maintain genomic stability in the context of DNA replication stress and DNA damage. We are interested in the molecular mechanisms underlying the cellular response to replication stress and DNA damage as well as the links between DNA damage and replication stress to human disease.

72 Total Publications
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Michael F. Clarke, M.D.

Karel H. and Avice N. Beekhuis Professor of Cancer Biology
Research Interests
Dr. Clarke maintains a laboratory focused on two areas of research: i) the control of self-renewal of normal stem cells and diseases such as cancer and hereditary diseases; and ii) the identification and characterization of cancer stem cells. His laboratory is investigating how perturbations of stem cell regulatory machinery contributes to human disease. In particular, the laboratory is investigating epigenetic regulators of self renewal, the process by which stem cells regenerate themselves.

180 Total Publications
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Dean W. Felsher

Professor of Medicine (Oncology) and of Pathology
Research Interests
My laboratory studies the molecular basis of cancer with a focus on understanding when cancer can be reversed through targeted oncogene inactivation.

207 Total Publications
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Margaret T. Fuller

Reed-Hodgson Professor of Human Biology, Katharine Dexter McCormick and Stanley McCormick Memorial Professor and Professor of Genetics and of Obstetrics/Gynecology (Reproductive and Stem Cell Biology)
Research Interests
Regulation of self-renewal, proliferation and differentiation in adult stem cell lineages. Developmental tumor suppressor mechanisms and regulation of the switch from proliferation to differentiation. Cell type specific transcription machinery and regulation of cell differentiation. Developmental regulation of cell cycle progression during male meiosis.

123 Total Publications
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Amato J. Giaccia

Jack, Lulu and Sam Willson Professor, Professor of Radiation Oncology, Emeritus
Research Interests
During the last five years, we have identified several small molecules that kill VHL deficient renal cancer cells through a synthetic lethal screening approach. Another major interest of my laboratory is in identifying hypoxia-induced genes involved in invasion and metastases. We are also investigating how hypoxia regulates gene expression epigenetically.

403 Total Publications
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Philip C. Hanawalt

Dr. Morris Herzstein Professor in Biology, Emeritus
Research Interests
My current interest includes two principal areas:

1. The molecular basis for diseases in which the pathway of transcription-coupled DNA repair is defective, including Cockyne syndrome (CS) and UV-sensitive syndrome (UVSS). Patients are severely sensitive to sunlight but get no cancers. See Hanawalt & Spivak, 2008, for review.

2. Transcription arrest by guanine-rich DNA sequences and non-canonical secondary structures. Transcription collisions with replication forks.

240 Total Publications
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Peter K. Jackson

Professor of Microbiology and Immunology (Baxter Labs) and of Pathology
Research Interests
Cell cycle and cyclin control of DNA replication .

172 Total Publications
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Yuan-Hung Lo

Postdoctoral Scholar, Hematology

22 Total Publications