Sriram Jayabal

Basic Life Research Scientist, Neurobiology

All Publications

Publications (10)

All Publications (10)
Journal Articles (9)
Books and Book Chapters (1)

Profiles With Related Publications

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Kwabena Boahen

Professor of Bioengineering, of Electrical Engineering and, by courtesy, of Computer Science
Research Interests
Boahen's group analyzes neural behavior computationally to elucidate principles of neural design at the cellular, circuit, and systems levels; and synthesizes neuromorphic electronic systems that scale energy-use with size as efficiently as the brain does. This interdisciplinary research program bridges neurobiology and medicine with electronics and computer science, bringing together these seemingly disparate fields.

43 Total Publications
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Axel Brunger

Professor of Molecular and Cellular Physiology, of Neurology, of Photon Science and, by courtesy, of Structural Biology
Research Interests
One of Axel Brunger's major goals is to decipher the molecular mechanisms of synaptic neurotransmitter release by conducting imaging and single-molecule/particle reconstitution experiments, combined with near-atomic resolution structural studies of the synaptic vesicle fusion machinery.

205 Total Publications
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Paul Buckmaster, DVM, PhD

Professor of Comparative Medicine and of Neurology
Research Interests
Mechanisms of epilepsy, especially temporal lobe epilepsy.

85 Total Publications
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Lu Chen

Professor of Neurosurgery and of Psychiatry and Behavioral Sciences
Research Interests
What distinguishes us humans from other animals is our ability to undergo complex behavior. The synapses are the structural connection between neurons that mediates the communication between neurons, which underlies our various cognitive function. My research program aims to understand the cellular and molecular mechanisms that underlie synapse function during behavior in the developing and mature brain, and how synapse function is altered during mental retardation.

62 Total Publications
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Shoa L. Clarke, MD, PhD

Assistant Professor of Medicine (Cardiovascular Medicine) and of Pediatrics
Clinical Focus
Preventive Cardiology, Genetics, Familial Hypercholesterolemia, Lipoprotein-a, Lipids, Coronary Artery Disease, Coronary Artery Calcification, Pediatrics, Cardiovascular Disease

44 Total Publications
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Maria Inmaculada Cobos Sillero

Associate Professor of Pathology
Clinical Focus
Anatomic Pathology, Neuropathology

47 Total Publications
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Karl Deisseroth

D. H. Chen Professor, Professor of Bioengineering and of Psychiatry and Behavioral Sciences
Clinical Focus
Psychiatry
Research Interests
Karl Deisseroth's laboratory created and developed optogenetics, hydrogel-tissue chemistry (beginning with CLARITY), and a broad range of enabling methods. He also has employed his technologies to discover the neural cell types and connections that cause adaptive and maladaptive behaviors.

526 Total Publications
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Jun Ding

Associate Professor of Neurosurgery and of Neurology
Research Interests
Neural circuits of movement control in health and movement disorders

50 Total Publications
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Shaul Druckmann

Associate Professor of Neurobiology, of Psychiatry and Behavioral Sciences and, by courtesy, of Electrical Engineering
Research Interests
Our research goal is to understand how dynamics in neuronal circuits relate and constrain the representation of information and computations upon it. We adopt three synergistic strategies: First, we analyze neural circuit population recordings to better understand the relation between neural dynamics and behavior, Second, we theoretically explore the types of dynamics that could be associated with particular network computations. Third, we analyze the structural properties of neural circuits.

35 Total Publications
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Chris Garcia

Younger Family Professor and Professor of Structural Biology
Research Interests
Structural and functional studies of transmembrane receptor interactions with their ligands in systems relevant to human health and disease - primarily in immunity, infection, and neurobiology. We study these problems using protein engineering, structural, biochemical, and combinatorial biology approaches.

348 Total Publications
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Shaul Hestrin, PhD

Professor of Comparative Medicine
Research Interests
The main interest of my lab is to understand how the properties of neocortical neurons, the circuits they form and the inputs they receive give rise to neuronal activity and behavior. Our approach includes behavioral studies, two-photon calcium imaging, in vivo whole cell recording in behaving animals and optogenetic methods to activate or to silence the activity of cortical neurons.

56 Total Publications
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John Huguenard

Professor of Neurology (Neurology Research Faculty), of Neurosurgery (Adult Neurosurgery) and, by courtesy, of Molecular and Cellular Physiology
Research Interests
We are interested in the neuronal mechanisms that underlie synchronous oscillatory activity in the thalamus, cortex and the massively interconnected thalamocortical system. Such oscillations are related to cognitive processes, normal sleep activities and certain forms of epilepsy. Our approach is an analysis of the discrete components (cells, synapses, microcircuits) that make up thalamic and cortical circuits, and reconstitution of components into in silico computational networks.

212 Total Publications