Sophia Chernikova

Sr Res Scientist-Basic Ls, Neurosurgery

Projects

• Role of microtubule-dependent cell trafficking in DNA repair and chemotherapy response of estrogen-negative breast cancer

Location

Stanford University
• Testing the efficacy of inhibitors of stromal derived factor 1 (SDF-1) pathway in post-irradiation treatment of breast cancer brain metastases

Location

Stanford University
• Role of SDF-1 mediated pathway in glioblastoma recurrence after whole-brain irradiation, Stanford University

Location

Stanford University
• Role of chromatin remodeling in radiation response and genomic instability

Location

Stanford University
• Development of a compound library screen aimed at finding small-molecule inhibitors of homologous recombination

Location

Stanford University
• Investigating mechanisms of action of hypoxia-activated cytotoxins, including the dinitrobenzamide mustard PR104A and tirapazamine

Identified homologous recombination pathway as a main pathway for repair of damage induced by a tirapazamine.

Location

Stanford University

Education & Certifications

MS, Engineer-Physicist, Moscow Institute of Physics and Technology, Applied Math and Physics (1990)
PhD, Colorado State University, Cell and Molecular Radiation Biology (1998)

All Publications

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Martin Brown

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Gilbert Chu

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Karlene Cimprich

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Gerald Crabtree

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Theresa Endres

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Or Gozani

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Philip C. Hanawalt

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