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Each cell of our bodies and of all multicellular organisms contains several members of the tetraspanin family. Tetraspanins provide a network that facilitates membranal interactions, hence their involvement in multiple physiological interactions. Our studies focus on CD81, which is required for cell fusion and cell-cell interactions, functions that have been subverted by major human pathogens, including hepatitis C virus and Plasmodium. Current research is aimed at understanding the role of CD81 in metastasis.
Clinical and Pathologic Studies in Non-Hodgkin's Lymphoma and Hodgkin's Disease
The purpose of this study is to characterize the molecular and cell biology of the tumor
cells in lymphoma.
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