Shigeki Nagai

Basic Life Research Scientist, Structural Biology

Honors & Awards

Postdoctoral fellowship, Swiss National Science Foundation (2009-2010)
Long term fellowship, Human Frontier Science Program (HFSP) (2010-2013)

Education & Certifications

Ph.D, Friedrich Miescher Institute, Basel, Switzerland, Molecular Biology (2009)
Master of Science, Kyoto University, Molecular Biology (2003)
Bachelor of Science, Kyoto University, Pharmaceutical Sciences (2001)

All Publications

Profiles With Related Publications

close
Umberto Aiello

Postdoctoral Scholar, Genetics

6 Total Publications
close
Patrick O. Brown

Professor of Biochemistry, Emeritus
Research Interests
Dr. Brown's research focuses on replacing humanity's most destructive invention - the use of animals as a food technology - by developing a new and better way to produce the world's most delicious, nutritious and affordable meats, fish and dairy foods directly from plants. He is also working on developing and scaling optimal methods for restoring healthy ecosystems and sequestering carbon on the 45% of Earth's surface that have been devastated by animal agriculture.

319 Total Publications
close
Dennis J Bua

Administrative Co-Director, School of Medicine - IDP's - MSTP

8 Total Publications
close
Anthony Cesnik

Postdoctoral Scholar, Bioengineering

25 Total Publications
close
Raymond Chen

Lead Undergraduate Advising Director, Academic Advising Operations

8 Total Publications
close
Sophia Chernikova

Sr Res Scientist-Basic Ls, Neurosurgery

19 Total Publications
close
Mike Cherry

Professor (Research) of Genetics, Emeritus
Research Interests
My research involves identifying, validating and integrating scientific facts into encyclopedic databases essential for research and scientific education. Published results of scientific experimentation are a foundation of our understanding of the natural world and provide motivation for new experiments. The combination of in-depth understanding reported in the literature with computational analyses is an essential ingredient of modern biological research.

148 Total Publications
close
Gilbert Chu

Professor of Medicine (Oncology) and of Biochemistry
Research Interests
After shuttering the wet lab, we have focused on: a point-of-care device to measure blood ammonia and prevent brain damage; a human protein complex that juxtaposes and joins DNA ends for repair and V(D)J recombination; and strategies for teaching students and for reducing selection bias in educational programs.

74 Total Publications
close
Karlene Cimprich

Professor of Chemical and Systems Biology and, by courtesy, of Biochemistry
Research Interests
Genomic instability contributes to many diseases, but it also underlies many natural processes. The Cimprich lab is focused on understanding how mammalian cells maintain genomic stability in the context of DNA replication stress and DNA damage. We are interested in the molecular mechanisms underlying the cellular response to replication stress and DNA damage as well as the links between DNA damage and replication stress to human disease.

78 Total Publications
close
Martha S. Cyert

Dr. Nancy Chang Professor
Research Interests
The Cyert lab is identifying signaling networks for calcineurin, the conserved Ca2+/calmodulin-dependent phosphatase, and target of immunosuppressants FK506 and cyclosporin A, in yeast and mammals. Cell biological investigations of target dephosphorylation reveal calcineurin’s many physiological functions. Roles for short linear peptide motifs, or SLiMs, in substrate recognition, network evolution, and regulation of calcineurin activity are being studied.

70 Total Publications
close
Hunter Fraser

Professor of Biology
Research Interests
We study the evolution of complex traits by developing new experimental and computational methods.

Our work brings together quantitative genetics, genomics, epigenetics, and evolutionary biology to achieve a deeper understanding of how genetic variation shapes the phenotypic diversity of life. Our main focus is on the evolution of gene expression, which is the primary fuel for natural selection. Our long-term goal is to be able to introduce complex traits into new species via genome editing.

94 Total Publications
close
Or Gozani

Dr. Morris Herzstein Professor
Research Interests
We study the molecular mechanisms by which chromatin-signaling networks effect nuclear and epigenetic programs, and how dysregulation of these pathways leads to disease. Our work centers on the biology of lysine methylation, a principal chromatin-regulatory mechanism that directs epigenetic processes. We study how lysine methylation events are generated, sensed, and transduced, and how these chemical marks integrate with other nuclear signaling systems to govern diverse cellular functions.

122 Total Publications