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Dr. Sethi is a Clinical Assistant Professor in the Department of Psychiatry and Behavioral Sciences and founding Director of the first academic Metabolic Psychiatry Clinical program in 2015. She is double board-certified in Psychiatry and Obesity Medicine and has additional expertise in adult eating disorders. She completed her residency in Psychiatry at Stanford University and specialized training in obesity at Duke Medical Center. Dr. Sethi received her MD jointly from Duke University School of Medicine and the National University of Singapore. She received a Masters degree in Biotechnology from Johns Hopkins University. Metabolic Psychiatry is a term she coined to describe an emerging clinical discipline focused on the integrative study and treatment of metabolic abnormalities and the relationship to mental illness. Dr. Sethi's approach to psychiatric treatment incorporates detection and treatment of metabolic abnormalities, principles of obesity medicine, nutrition and metabolism. She was awarded funding by the Obesity Treatment Foundation and Baszucki Brain Foundation as principal investigator to study the effectiveness of a low - carbohydrate ketogenic dietary intervention in an outpatient cohort of patients with obesity or metabolic dysfunction overlapping with bipolar illness or schizophrenia. She is also a co-investigator on a pilot randomized clinical trial testing an FDA-approved obesity medication for binge-eating disorder and bulimia nervosa at Stanford University funded by SPARK. She is a recipient of the Kuen Lau Bipolar Research Award and the Symonds Fellow Award from the Association of Women Psychiatrists for innovation in psychiatry and contributions to women’s health. She is a member of the Obesity Medicine Association, the American Psychiatric Association, and served on the council of the Northern California Psychiatric Association.
Improving metabolic and mental health through dietary interventions, pharmacological optimization, and other lifestyle means in those with severe mental illness, such as bipolar disorder or schizophrenia is a major focus of her research. Clinical and academic interests are also in the management of psychiatric disorders with co-morbid obesity, poor metabolic health and/or eating disorders, particularly binge eating disorder and bulimia nervosa.
Impact of a Ketogenic Diet on Metabolic and Psychiatric Health in Patients With Bipolar or Schizophrenia Illness
To initiate a low-carbohydrate, high-fat (LCHF) or ketogenic dietary (KD) intervention among
a cohort of outpatients with either schizophrenia or bipolar illness who also have metabolic
abnormalities, overweight/obesity, and/or are currently taking psychotropic medications
experiencing metabolic side effects.
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FDA Approved Medication to Reduce Binge Eating and/or Purging
This study will demonstrate the efficacy of Qsymia versus placebo in treating bulimia nervosa
and binge eating disorder.
Stanford is currently not accepting patients for this trial.
For more information, please contact Debra L Safer, MD, 650-723-7928.