Professional Interests
I utilize an integrative biological-mathematical-engineering approach to study the growth, development, early detection, and treatment of cancer. This includes:
1. The development of animal models of cancer, including subcutaneous and orthotopic xenograft cancer mouse models (primarily breast and ovarian cancer).
2. The detection of circulating biomarkers in blood and urine.
3. Molecular and anatomical imaging of cancer, including in vivo imaging modalities such as bioluminescence, fluorescence and ultrasound.
4. The development of mathematical models of cancer, with focus on parameter estimation and identifiability, hypothesis testing and discrimination, and nonlinear optimization.
