Bio
I am a family doctor and physician scientist interested in translational research to improve preventive health and public health strategies to improve population health. My research focuses on the integration of clinical and translational research into nicotine dependence using genomic and neuromaging investigations to identify and validate biomarkers for smoking cessation, to reduce health disparities in cardiovascular disease and cancer, and to employ community engagement and clinical implementation science approaches to fill critical gaps in preventive medicine. Recent work includes the identification of a genome-wide significant genetic marker for smoking intensity in African Americans that is associated with pharmacogenetic treatment response for smoking cessation and risk of lung cancer in African Americans. Current and future research is translating evidence in systematic reviews and meta-analyses to evidence-based guidelines, investigations of publication bias and proposed reforms to improve the fidelity of research through open science, and training the primary care workforce in core competencies of genetic medicine to enable precision health for all. Born and raised in Seattle, I love the west and Pac-12 football, fishing, sailing, marathon running and rowing.
Clinical Focus
- Precision Health
- Family Medicine
- Pharmacogenomics
- Tobacco Treatment
Academic Appointments
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Associate Professor - Med Center Line, Medicine - Primary Care and Population Health
Administrative Appointments
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Member, Stanford Cancer Institute (2016 - Present)
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Associate Professor of Medicine, Stanford University School of Medicine (2014 - Present)
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Member Affiliate, Meta-Research Innovation Center at Stanford (METRICS) (2014 - Present)
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Clinical Associate Professor (secondary appointment), Stanford Prevention Research Center (2011 - Present)
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Physician curator, PharmGKB (2010 - 2011)
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Adjunct Associate Professor of Family Medicine, Brown Alpert Medical School (2009 - 2014)
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Clinical Associate Professor of Family & Community Medicine, Stanford University School of Medicine (2009 - 2014)
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Director of C. Everett Koop Health Policy Fellowship, Brown Alpert Medical School (2003 - 2009)
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Director of Primary Care Genetics Laboratory & Translational Research Center, Memorial Hospital of Rhode Island/Brown Alpert Medical School (2002 - 2009)
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Assistant Professor of Family Medicine, Brown Alpert Medical School (2001 - 2009)
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Instructor of Family Medicine, Brown Alpert Medical School (1999 - 2001)
Honors & Awards
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Family Practice Scholar Award, Glaxo-Wellcome (1997)
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Deans Teaching Excellence Award, Brown Alpert Medical School (2001)
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Advanced Research Training Award, American Academy of Family Physicians (2001-2003)
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Profiles in Competence Teaching Award, Brown Alpert Medical School (2002)
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Generalist Physician Faculty Scholars Award, Robert Wood Johnson Foundation (2002-2006)
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K08 Mentored Clinical Scientist Development Award, National Institute on Drug Abuse/National Institutes of Health (2002-2008)
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MCR President, Green College, University of Oxford (2004-2005)
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Benjamin Meaker Visiting Professorship, University of Bristol (2010)
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James C. Puffer, M.D./ABFM/National Academy of Medicine Anniversary Fellow, National Academies of Science, Engineering, and Medicine (2011-2013)
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Board of US BMJ Fellows, BMJ Group (2013)
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Fellow, American Academy of Family Physicians, American Academy of Family Physicians (2017)
Boards, Advisory Committees, Professional Organizations
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US Board of BMJ Fellows, British Medical Journal (2013 - Present)
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Young Leaders Advisory Group, American Board of Family Medicine (2010 - Present)
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Smoking Cessation Guideline Panel, National Comprehensive Cancer Network (2014 - Present)
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Scientific Advisory Committee, Tobacco-Related Disease Research Program - University of California Office of the President (2013 - 2015)
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Committee on the Evidence Base for Genetic Testing, National Academy of Medicine (2015 - 2017)
Professional Education
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BS, University of Washington, Zoology (1990)
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Medical Education:University of Washington School of Medicine (1995) WA
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Internship:NH Dartmouth Family Practice Residency (1996) NH
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Residency:NH Dartmouth Family Practice Residency (1998) NH
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Board Certification: Family Medicine, American Board of Family Medicine (1998)
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SM, Harvard School of Public Health, Health & Social Behavior (1999)
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Fellowship, Cancer Research UK GPRG, University of Oxford, Pharmacogenetics (2002)
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Fellowship, C. Everett Koop Institute at Dartmouth, Tobacco Control (2002)
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Fellowship, American Academy of Family Physicians, Advanced Research Training (2003)
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Board Recertification, Family Medicine, American Board of Family Medicine (2005)
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Fellowship, Robert Wood Johnson Foundation Generalist Physician Faculty Scholar, Pharmacogenetics of Smoking Cessation in Primary Care (2006)
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Professional Education:University of Oxford (2006) UK
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Fellowship, NIDA K08 Mentored Clinical Scientist, Nicotine Dependence (2007)
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Fellowship, National Academies of Sciences, Engineering, and Medicine, Health Policy (James C. Puffer, M.D./American Board of Family Medicine/National Academy of Medicine Anniversary Fellow) (2013)
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Board Recertification, Family Medicine, American Board of Family Medicine (2015)
Community and International Work
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Stanford Precision Health for Ethnic and Racial Equity Center (SPHERE), Bay Area and South Dakota
Topic
Precision health, health disparities
Partnering Organization(s)
National Institute on Minority Health and Health Disparities/National Institutes of Health
Populations Served
Asians, African-Americans, Latino/Hispanics, Native Americans
Location
International
Ongoing Project
Yes
Opportunities for Student Involvement
Yes
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Study of Tobacco Use in Minority Populations (STOMP) Genetics Consortium, US
Topic
Genetics, Smoking, African Americans
Partnering Organization(s)
SRI International, Memorial Sloan-Kettering Cancer Center, Brown University and other institutions.
Populations Served
African Americans
Location
International
Ongoing Project
No
Opportunities for Student Involvement
No
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CYP2A6 genotype and smoking in China, Guangzhou, P.R. China
Topic
Genetic influences on smoking
Partnering Organization(s)
Sun Yat-sen University; University of Toronto
Location
International
Ongoing Project
No
Opportunities for Student Involvement
No