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My research primarily focuses on clinical translational science of infectious diseases with an emphasis on tuberculosis and SARS-CoV-2. I leverage multiplex qPCR, whole genome sequencing and mass spectrometry-based technologies to develop novel diagnostics for pathogen detection and personalize TB treatment by pharmacogenomic analysis. In addition, I develop and test innovative approaches to study transmission of infectious diseases and evaluate control measures in congregate/community settings. Key Research:i)Development and validation of molecular viability assays for detection and quantification of novel SARS-CoV-2 virus in COVID-19 patients ii)Development and validation of a novel aerosol capture tool for the detection of SARS-CoV-2 in exhaled breath from COVID-19 patients with mild and severe symptomsiii)Development of a rapid pharmacogenomic assay to detect NAT2 polymorphisms and predict INH acetylation to guide dosing for tuberculosis treatmentiv)Detection of M. tuberculosis in the environment as a novel tool for identifying high-risk locations for tuberculosis transmissionv)Analyzing host serum biomarkers in latent and active Tuberculosis using ELISA assays in patients as a measure of disease severity.