School of Medicine

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  • Zhen Cheng

    Zhen Cheng

    Associate Professor (Research) of Radiology (General Radiology)

    Current Research and Scholarly Interests To develop novel molecular imaging probes and techniques for non-invasively early detection of cancer using multimodality imaging technologies including PET, SPECT, MRI, optical imaging, etc.

  • Frederick T. Chin, Ph.D.

    Frederick T. Chin, Ph.D.

    Assistant Professor (Research) of Radiology (General Radiology)

    Current Research and Scholarly Interests Our group's primary objectives are:

    1) Novel radioligand and radiotracer development.
    We will develop novel PET (Positron Emission Tomography) imaging agents with MIPS and Stanford faculty as well as other outside collaborations including academia and pharmaceutical industry. Although my personal research interests will be to discover and design of candidate probes that target molecular targets in the brain, our group focus will primarily be on cancer biology and gene therapy. In conjunction with our state-of-the-art imaging facility, promising candidates will be evaluated by PET-CT/MR imaging in small animals and primates. Successful radioligands and/or radiotracers will be extended towards future human clinical applications.

    2) Designing new radiolabeling techniques and methodologies.
    We will aim to design new radiolabeling techniques and methodologies that may have utility for future radiopharmaceutical development in our lab and the general radiochemistry community.

    3) Radiochemistry production of routine clinical tracers.
    Since we also have many interests with many Stanford faculty and outside collaborators, our efforts will also include the routine radiochemistry production of many existing radiotracers for human and non-human use. Our routine clinical tracers will be synthesized in custom-made or commercial synthetic modules (i.e. GE TRACERlab modules) housed in lead-shielded cells and be distributed manually or automatically (i.e. Comecer Dorothea) to our imagers.

  • Sanjiv Sam Gambhir, MD, PhD

    Sanjiv Sam Gambhir, MD, PhD

    Virginia and D.K. Ludwig Professor for Clinical Investigation in Cancer Research and Professor, by courtesy, of Bioengineering and of Materials Science and Engineering

    Current Research and Scholarly Interests My laboratory focuses on merging advances in molecular biology with those in biomedical imaging to advance the field of molecular imaging. Imaging for the purpose of better understanding cancer biology and applications in gene and cell therapy, as well as immunotherapy are all being studied. A key long-term focus is the earlier detection of cancer by combining in vitro diagnostics and molecular imaging.

  • Michael L. Goris

    Michael L. Goris

    Professor of Radiology (Nuclear Medicine), Emeritus

    Current Research and Scholarly Interests Radio-immunotherapy. Medical Imaging Processing. Quantification for diagnosis Clinical validations

  • Michelle L. James, PhD

    Michelle L. James, PhD

    Instructor, Radiology- Molecular Imaging Program at Stanford

    Current Research and Scholarly Interests My research is focused on developing and evaluating molecular imaging agents to improve the way we diagnose, treat, and understand brain diseases.

  • Sri-Rajasekhar (Raj) Kothapalli, PhD

    Sri-Rajasekhar (Raj) Kothapalli, PhD

    Instructor, Radiology- Molecular Imaging Program at Stanford

    Current Research and Scholarly Interests My current research is focused on developing non-ionizing and low cost medical technologies that reliably detect the disease and also capable of predicting the prognosis. Towards this goal, I work at the interface of Photonics, Acoustics, MEMS, Molecular Imaging, Medical Imaging and Computing. Equal emphasis is on translating these technologies for pre-clinical and clinical applications in cancer and neurological diseases.

    At Stanford, I invented a transrectal ultrasound and photoacoustic (TRUSPA) device for imaging human prostate using capacitive micromachined ultrasonic transducer (CMUT) array technology. Pilot clinical studies on prostate cancer patients demonstrated that the device is capable of simultaneously displaying anatomical and molecular information of the prostate. Currently, relevant molecular imaging approaches are being investigated to further improve the sensitivity and the specificity of the prostate cancer detection. Similarly, I also developed an intra-operative ultrasound and photoacoustic (iUSPA) device that is in the path to clinical translation for various applications.

    My other research interests include Cerenkov luminescence imaging, and developing novel microscopy and in vitro diagnostic techniques for probing complex cell signaling pathways.

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