Bio
I am a physician-scientist and the overall theme my research has been the genetic basis of cardiovascular disease across the continuum from Discovery to the development of Model Systems to the Translation of these findings to the clinic and most recently to the Public Health aspect of genetics. I completed his MD-PhD at UNC with Prof. Nobuyo Maeda and Nobel Laureate Oliver Smithies. I did Internal Medicine residency and Cardiology fellowship training at Stanford working with Dr. Tom Quertermous. Currently my Discovery and basic translational efforts center on understanding the genetic basis of insulin resistance using GWAS studies coupled with exploration in model systems including iPSCs and CRISPR screens. My clinical translational focus is on Familial Hypercholesterolemia (FH) and I am the volunteer Chief Medical Advisor of the FH Foundation (FHF) which is a patient-led organization dedicated to increasing awareness of FH, identifying and treating patients with FH and screening family members to prevent deleterious outcomes. I helped lead the FHF efforts to establish a national patient registry (CASCADE FH), apply for an ICD10 code for FH and am now using cutting-edge ?big-data? approaches to identify previously undiagnosed FH patients in electronic medical records (FIND FH). I have published over 90 papers with research projects currently funded by the National Institutes of Health, the American Diabetes Association, the American Heart Association and the Doris Duke Charitable Foundation.
Clinical Focus
- Cardiology
- Insulin Resistance
- Familial Hypercholesterolemia
- Cardiovascular Disease
- Genetics
Academic Appointments
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Assistant Professor - Med Center Line, Medicine - Cardiovascular Medicine
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Member, Bio-X
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Member, Cardiovascular Institute
Administrative Appointments
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Co-Section Chief. Metabolism and Insulin Signaling, Stanford Diabetes Research Center` (2017 - Present)
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Program Director, Cardiovascular Medicine Fellowship Program (2018 - Present)
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Co-Director, Translational Investigator Program (2017 - Present)
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Chief, Translational Medicine, The FH Foundation (2012 - Present)
Honors & Awards
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National Innovative Research Award, AHA
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Dean's Fellowship, Stanford (2005)
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Clinical Scholar, Doris Duke Charitable Foundation (6/1/16-6/1/19)
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Fellowship Award, Future Leaders in CV Medicine (2006)
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Alderman Award for Excellence in Clinical Research, Stanford Cardiovascular Medicine (2008, 2009)
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Diplomate, National Lipid Association (2012)
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Fellow, AHA (2012)
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Fellow, ACC (2012)
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National Fellow to Faculty Transition Award, AHA (7/1/10-7/1/15)
Boards, Advisory Committees, Professional Organizations
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Board Member, The FH Foundation (2012 - Present)
Professional Education
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Fellowship: Stanford University Cardiovascular Medicine Fellowship (2010) CA
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Residency: Stanford University Internal Medicine Residency (2005) CA
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Board Certification: American Board of Internal Medicine, Cardiovascular Disease (2010)
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Medical Education: University of North Carolina - Chapel Hill (2003) NC
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PhD, University of North Carolina, Chapel Hill, Genetics and Molecular Biology (2001)
Community and International Work
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The FH Foundation
Topic
Familial Hypercholesterolemia
Partnering Organization(s)
The FH Foundation
Location
International
Ongoing Project
No
Opportunities for Student Involvement
No
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Arbor Free Clinic
Location
Bay Area
Ongoing Project
Yes
Opportunities for Student Involvement
Yes