School of Medicine


Showing 1-6 of 6 Results

  • Julien Sage

    Julien Sage

    Professor of Pediatrics (Hematology/Oncology) and of Genetics

    Current Research and Scholarly Interests We investigate the mechanisms by which normal cells become tumor cells, and we combine genetics, genomics, and proteomics approaches to investigate the differences between the proliferative response in response to injury and the hyperproliferative phenotype of cancer cells and to identify novel therapeutic targets in cancer cells.

  • Gavin Sherlock

    Gavin Sherlock

    Associate Professor of Genetics

    Current Research and Scholarly Interests Evolution and the adaptive landscape using yeast as a model; Defining yeast transcriptomes; chromosomal evolution in hybrid yeast species

  • Arend Sidow

    Arend Sidow

    Professor of Pathology and of Genetics

    Current Research and Scholarly Interests We have a highly collaborative research program in the evolutionary genomics of cancer. We apply well-established principles of phylogenetics to cancer evolution on the basis of whole genome sequencing and functional genomics data of multiple tumor samples from the same patient. Introductions to our work and the concepts we apply are best found in the Newburger et al paper in Genome Research and the Sidow and Spies review in TIGS.

    More information can be found here: http://www.sidowlab.org

  • Michael Snyder

    Michael Snyder

    Stanford W. Ascherman, MD, FACS, Professor in Genetics

    Current Research and Scholarly Interests Our laboratory use different omics approaches to study a) regulatory networks, b) intra- and inter-species variation which differs primarily at the level of regulatory information c) human health and disease. For the later we have established integrated Personal Omics Profiling (iPOP), an analysis that combines longitudinal analyses of genomic, transcriptomic, proteomic, metabolomic, DNA methylation, microbiome and autoantibody profiles to monitor healthy and disease states

  • Tim Stearns

    Tim Stearns

    Frank Lee and Carol Hall Professor and Professor of Genetics

    Current Research and Scholarly Interests We use the tools of genetics, microscopy, and biochemistry to understand fundamental questions of cell biology: How are cells organized by the cytoskeleton? How do the centrosome and cilium control cell control cell signaling? How is cell division coordinated with duplication of the centrosome, and what goes wrong in cancer cells defective in this coordination?

  • Lars Steinmetz

    Lars Steinmetz

    Professor of Genetics

    Current Research and Scholarly Interests We apply diverse genomic approaches to understand how genetic variation affects health and disease by: 1) functional and mechanistic analyses of gene regulation, 2) studies of meiotic recombination and inheritance, 3) analyses of genetic and environmental interactions, and 4) characterization of diseases in human cells and model organisms. We integrate wet lab and computational genomic, transcriptomic, proteomic and metabolic approaches, and develop technologies to enable personalized medicine.

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