School of Medicine
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Professor of Pediatrics (Cardiology) at the Lucile Salter Packard Children's Hospital and at the Stanford University Medical Center
Current Research and Scholarly Interests Dr. Murphy's major interests are in noninvasive cardiology and clinical pediatric and adult congenital cardiac disease. These clinical interests range from imaging of complex cardiac disease in the fetus and newborn to care of the adult with congenital heart disease. He also coordinates the Marfan clinic at LPCH. He is the director of the Adult Congenital Cardiac Clinic at Stanford University Medical Center.
Greer Murphy M.D., Ph.D.
Professor of Psychiatry and Behavioral Sciences (General Psychiatry and Psychology-Adult), Emeritus
Current Research and Scholarly Interests Pharmacogenetics of mood disorders and nicotine addiction. Microglial neurotoxicity and neuroprotection in Alzheimer's disease. Genome wide expression analysis of mouse models for Alzheimer's disease.
Kelly P. Murphy, MD
Clinical Associate Professor, Emergency Medicine
Current Research and Scholarly Interests Global Health: rural healthcare delivery systems and grassroots health education.
Medical Development: collaborating with an international team of NGOs to rebuild the national healthcare system in Papua New Guinea.
Professor of Medicine (Biomedical Informatics) and of Biomedical Data Science
Current Research and Scholarly Interests There are great opportunities for new discoveries and for ensuring the reproducibility of scientific results when experimental data?and descriptions of the methods used to generate and analyze those data?are available in public repositories. Our laboratory is studying the development of new methods to aid investigators in creating more comprehensive online descriptions both of their data and of their experiments that can be processed both by other scientists and by computers.
Assistant Professor, Otolaryngology - Head & Neck Surgery Divisions
Current Research and Scholarly Interests Hearing is one of the most sensitive functions controlled by thyroid hormone (TH). TH is required for the timely coordination of a complex set of differentiation events in the maturing cochlea. Hypothyroidism retards the differentiation of the cochlea, including synaptogenesis, neurogenesis and myelinogenesis. The mechanisms that prompt the progression of these developmental events are poorly understood. Our preliminary data shows that many genes are differentially regulated by thyroid hormone in the cochlea.
Identifying which of these genes play important roles in cochlear hair cell innervation and synapse formation will further basic understanding about how the auditory system develops. In addition, knowledge of these genes could help devise strategies for stimulating the innervation of newly generated hair cells. To establish or restore hearing, it is vital that newly formed hair cells be connected functionally to the brain. We expect that our research will contribute to this important clinical/translational research effort by identifying genes involved in stimulating innervation and synapse formation.
Professor of Medicine (Nephrology), Emeritus
Current Research and Scholarly Interests A novel approach is used to evaluate glomerular disease in humans, and its progression. A combination of physiologic techniques, a morphometric analysis of glomeruli obtained by biopsy, and mathematical modeling of glomerular ultrafiltration is used to quantify the extent of glomerular injury in humans for the first time.