School of Medicine
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Jin Hyung Lee
Associate Professor of Neurology, of Neurosurgery and of Bioengineering and, by courtesy, of Electrical Engineering
Current Research and Scholarly Interests In vivo visualization and control of neural circuits
Current Research and Scholarly Interests One of the key characteristics of life is the dynamic cross-scale interactions across different levels of biological organization, such as molecules, genes, cells, tissues, organs and an organism, in their own multi-scaled environmental contexts. The dynamic property of these interactions results in variation in physiological traits across individuals, shaping individuality of an organism. The overall research direction of my laboratory is to establish in vitro experimental platforms in which we can investigate this cross-scale interaction efficiently to develop personalized therapeutic strategies. Because many aspects of cross-scale interactions are mediated by blood circulation and crosstalk between the vasculature and perivascular tissues, our current efforts are focused on engineering the functional vasculatures in pathophysiological conditions of various human tissues. We have successfully developed in vitro experimental models equipped with the capacity of real-time monitoring of individual cell behaviors, which enables effective identification of the vascular routes that induce desirable behaviors of endogenous or exogenously grafted cells. Our in vitro model allows precise and independent control of the experimental parameters in highly time- and cost- efficient ways and facilitates the development of therapeutic and preventive treatment strategies in consideration of the phenotype variations across the patient population.
Clinical Professor, Anesthesiology, Perioperative and Pain Medicine
Current Research and Scholarly Interests - Intrathecal / Intraspinal Analgesics
- Ziconotide (Prialt)
- Industry-supported clinical trials
Gordon Li, MD
Associate Professor of Neurosurgery and, by courtesy, of Neurology and of Otolaryngology-Head and Neck Surgery at the Stanford University Medical Center
Current Research and Scholarly Interests 1.) My laboratory studies the biology of brain tumors with the goal of developing novel therapeutics for the treatment of malignant brain tumors and translating that research into clinical trials.
2.) My clinical interests include improving surgical techniques for brain tumor surgery, immunotherapy for the treatment of glioblastoma, and novel uses for stereotactic radiosurgery.
Frank M. Longo, MD, PhD
George E. and Lucy Becker Professor in Medicine and Professor, by courtesy, of Neurosurgery
Current Research and Scholarly Interests Clinical interests include Alzheimer's disease and Huntington's disease and the development of effective therapeutics for these disorders. Laboratory interests encompass the elucidation of signaling mechanisms relevant to neurodegenerative disorders and the development of novel small molecule approaches for the treatment of neurodegenerative and other neurological disorders.