Bio

Honors & Awards


  • Young Investigator Award (semifinalist), 2014 ISMRM Annual Meeting (2014)
  • Best Paper Award (runner-up), ISMRM Workshop on Data Sampling & Image Reconstruction (2013)
  • Best Poster Award (2nd place), 2011 ISMRM Annual Meeting (2011)
  • Educational Stipend Award, ISMRM Annual Meetings (2010,2011,2013)
  • Stanford Graduate Engineering Fellowship, Stanford University (2008-2009)
  • Excellence Graduate Honors, Tsinghua University (2008)
  • Meritorious Winner, Mathematical Contest in Modeling (2007)

Boards, Advisory Committees, Professional Organizations


  • Trainee Member, International Society of Magnetic Resonance in Medicine (ISMRM) (2009 - Present)

Professional Education


  • Doctor of Philosophy, Stanford University, EE-PHD (2014)
  • Master of Science, Stanford University, EE-MS (2010)
  • Bachelor of Engineering, Tsinghua University, Biomedical Engineering (2008)

Patents


  • Tao Zhang, Michael Lustig, John M. Pauly, Shreyas S. Vasanawala. "United States Patent 8,638,096 Method of autocalibrating parallel imaging interpolation from arbitrary K-space sampling with noise correlations weighted to reduce noise of reconstructed images", Leland Stanford Junior University, Jan 28, 2014
  • Tao Zhang, Michael Lustig, Shreyas S Vasanawala, John M Pauly. "United States Patent 8,538,115 Coil compression for three dimensional autocalibrating parallel imaging with cartesian sampling", Leland Stanford Junior University, Sep 17, 2013

Publications

Journal Articles


  • Clinical Performance of Contrast Enhanced Abdominal Pediatric MRI With Fast Combined Parallel Imaging Compressed Sensing Reconstruction JOURNAL OF MAGNETIC RESONANCE IMAGING Zhang, T., Chowdhury, S., Lustig, M., Barth, R. A., Alley, M. T., Grafendorfer, T., Calderon, P. D., Robb, F. J., Pauly, J. M., Vasanawala, S. S. 2014; 40 (1): 13-25

    Abstract

    To deploy clinically, a combined parallel imaging compressed sensing method with coil compression that achieves a rapid image reconstruction, and assess its clinical performance in contrast-enhanced abdominal pediatric MRI.With Institutional Review Board approval and informed patient consent/assent, 29 consecutive pediatric patients were recruited. Dynamic contrast-enhanced MRI was acquired on a 3 Tesla scanner using a dedicated 32-channel pediatric coil and a three-dimensional SPGR sequence, with pseudo-random undersampling at a high acceleration (R = 7.2). Undersampled data were reconstructed with three methods: a traditional parallel imaging method and a combined parallel imaging compressed sensing method with and without coil compression. The three sets of images were evaluated independently and blindly by two radiologists at one siting, for overall image quality and delineation of anatomical structures. Wilcoxon tests were performed to test the hypothesis that there was no significant difference in the evaluations, and interobserver agreement was analyzed.Fast reconstruction with coil compression did not deteriorate image quality. The mean score of structural delineation of the fast reconstruction was 4.1 on a 5-point scale, significantly better (P < 0.05) than traditional parallel imaging (mean score 3.1). Fair to substantial interobserver agreement was reached in structural delineation assessment.A fast combined parallel imaging compressed sensing method is feasible in a pediatric clinical setting. Preliminary results suggest it may improve structural delineation over parallel imaging. J. Magn. Reson. Imaging 2014;40:13-25. 2013 Wiley Periodicals, Inc.

    View details for DOI 10.1002/jmri.24333

    View details for Web of Science ID 000337640700003

    View details for PubMedID 24127123

  • Accelerating Parameter Mapping with a Locally Low Rank Constraint Magnetic Resonance in Medicine Zhang, T., Pauly, J. M., Levesque, I. R. 2014

    View details for DOI 10.1002/mrm.25161

  • Venous and arterial flow quantification are equally accurate and precise with parallel imaging compressed sensing 4D phase contrast MRI JOURNAL OF MAGNETIC RESONANCE IMAGING Tariq, U., Hsiao, A., Alley, M., Zhang, T., Lustig, M., Vasanawala, S. S. 2013; 37 (6): 1419-1426

    Abstract

    To evaluate the precision and accuracy of parallel-imaging compressed-sensing 4D phase contrast (PICS-4DPC) magnetic resonance imaging (MRI) venous flow quantification in children with patients referred for cardiac MRI at our children's hospital.With Institutional Review Board (IRB) approval and Health Insurance Portability and Accountability Act (HIPAA) compliance, 22 consecutive patients without shunts underwent 4DPC as part of clinical cardiac MRI examinations. Flow measurements were obtained in the superior and inferior vena cava, ascending and descending aorta, and the pulmonary trunk. Conservation of flow to the upper, lower, and whole body was used as an internal physiologic control. The arterial and venous flow rates at each location were compared with paired t-tests and F-tests to assess relative accuracy and precision.Arterial and venous flow measurements were strongly correlated with the upper (? = 0.89), lower (? = 0.96), and whole body (? = 0.97); net aortic and pulmonary trunk flow rates were also tightly correlated (? = 0.97). There was no significant difference in the value or precision of arterial and venous flow measurements in upper, lower, or whole body, although there was a trend toward improved precision with lower velocity-encoding settings.With PICS-4DPC MRI, the accuracy and precision of venous flow quantification are comparable to that of arterial flow quantification at velocity-encodings appropriate for arterial vessels. J. Magn. Reson. Imaging 2013;37:1419-1426. 2012 Wiley Periodicals, Inc.

    View details for DOI 10.1002/jmri.23936

    View details for Web of Science ID 000319420000016

    View details for PubMedID 23172846

  • Coil compression for accelerated imaging with Cartesian sampling MAGNETIC RESONANCE IN MEDICINE Zhang, T., Pauly, J. M., Vasanawala, S. S., Lustig, M. 2013; 69 (2): 571-582

    Abstract

    MRI using receiver arrays with many coil elements can provide high signal-to-noise ratio and increase parallel imaging acceleration. At the same time, the growing number of elements results in larger datasets and more computation in the reconstruction. This is of particular concern in 3D acquisitions and in iterative reconstructions. Coil compression algorithms are effective in mitigating this problem by compressing data from many channels into fewer virtual coils. In Cartesian sampling there often are fully sampled k-space dimensions. In this work, a new coil compression technique for Cartesian sampling is presented that exploits the spatially varying coil sensitivities in these nonsubsampled dimensions for better compression and computation reduction. Instead of directly compressing in k-space, coil compression is performed separately for each spatial location along the fully sampled directions, followed by an additional alignment process that guarantees the smoothness of the virtual coil sensitivities. This important step provides compatibility with autocalibrating parallel imaging techniques. Its performance is not susceptible to artifacts caused by a tight imaging field-of-view. High quality compression of in vivo 3D data from a 32 channel pediatric coil into six virtual coils is demonstrated.

    View details for DOI 10.1002/mrm.24267

    View details for Web of Science ID 000314059500031

    View details for PubMedID 22488589

  • Fast pediatric 3D free-breathing abdominal dynamic contrast enhanced MRI with high spatiotemporal resolution. Journal of magnetic resonance imaging : JMRI Zhang, T., Cheng, J. Y., Potnick, A. G., Barth, R. A., Alley, M. T., Uecker, M., Lustig, M., Pauly, J. M., Vasanawala, S. S. 2013

    Abstract

    To develop a method for fast pediatric 3D free-breathing abdominal dynamic contrast enhanced (DCE) magnetic resonance imaging (MRI) and investigate its clinical feasibility.A combined locally low rank parallel imaging method with soft gating is proposed for free-breathing DCE MRI acquisition. With Institutional Review Board (IRB) approval and informed consent/assent, 23 consecutive pediatric patients were recruited for this study. Free-breathing DCE MRI with ?1 mm(3) spatial resolution and a 6.5-sec frame rate was acquired on a 3T scanner. Undersampled data were reconstructed with a compressed sensing method without motion correction (FB-CS) and the proposed method (FB-LR). A follow-up respiratory-triggered acquisition (RT-CS) was performed as a reference standard. The reconstructed images were evaluated independently by two radiologists. Wilcoxon tests were performed to test the hypothesis that there was no significant difference between different reconstructions. Quantitative evaluation of contrast dynamics was also performed.The mean score of overall image quality of FB-LR was 4.0 on a 5-point scale, significantly better (P < 0.05) than FB-CS reconstruction (mean score 2.9), and similar to RT-CS (mean score 4.1). FB-LR also matched the temporal fidelity of contrast dynamics with a root mean square error less than 5%.Fast 3D free-breathing DCE MRI with high scan efficiency and image quality similar to respiratory-triggered acquisition is feasible in a pediatric clinical setting.J. Magn. Reson. Imaging 2013. 2013 Wiley Periodicals, Inc.

    View details for DOI 10.1002/jmri.24551

    View details for PubMedID 24375859

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