Honors & Awards

  • Marie Curie doctoral training fellowship, European Union (2010)

Professional Education

  • Bachelor of Science, Universite Des Sciences & Techniques (2008)
  • Doctor of Philosophy, University Of Bristol (2014)
  • Master of Science, Universite De Bordeaux Ii (2010)

Stanford Advisors

Research & Scholarship

Lab Affiliations


All Publications

  • mGlu1 Receptor-Induced LTD of NMDA Receptor Transmission Selectively at Schaffer Collateral-CA1 Synapses Mediates Metaplasticity. The Journal of neuroscience : the official journal of the Society for Neuroscience Bhouri, M., Farrow, P. A., Motee, A., Yan, X., Battaglia, G., Di Menna, L., Riozzi, B., Nicoletti, F., Fitzjohn, S. M., Bashir, Z. I. 2014; 34 (36): 12223-9


    Hippocampal CA1 pyramidal neurons receive inputs from entorhinal cortex directly via the temporoammonic (TA) pathway and indirectly via the Schaffer collateral (SC) pathway from CA3. NMDARs at synapses of both pathways are critical for the induction of synaptic plasticity, information processing, and learning and memory. We now demonstrate that, in the rat hippocampus, activity-dependent mGlu1 receptor-mediated LTD (mGlu1-LTD) of NMDAR-mediated transmission (EPSCNMDA) at the SC-CA1 input prevents subsequent LTP of AMPAR-mediated transmission. In contrast, there was no activity-dependent mGlu1-LTD of EPSCNMDA at the TA-CA1 pathway, or effects on subsequent plasticity of AMPAR-mediated transmission. Therefore, the two major pathways delivering information to CA1 pyramidal neurons are subject to very different plasticity rules.

    View details for DOI 10.1523/JNEUROSCI.0753-14.2014

    View details for PubMedID 25186764

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