School of Medicine
Showing 1-32 of 32 Results
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Laura Attardi
Professor of Radiation Oncology (Radiation and Cancer Biology) and of Genetics
Current Research and Scholarly Interests Our research is aimed at defining the pathways of p53-mediated apoptosis and tumor suppression, using a combination of biochemical, cell biological, and mouse genetic approaches. Our strategy is to start by generating hypotheses about p53 mechanisms of action using primary mouse embryo fibroblasts (MEFs), and then to test them using gene targeting technology in the mouse.
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Sharon Clarke
Administrative Associate, Radiation Oncology - Radiation Biology
Current Role at Stanford Admin Support for Dr. Amato Giaccia
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Richard Frock
Assistant Professor of Radiation Oncology (Radiation and Cancer Biology)
Current Research and Scholarly Interests Mechanisms of DNA double-strand break repair and chromosomal translocations
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Amato J. Giaccia
Jack, Lulu and Sam Willson Professor, Professor of Radiation Oncology, Emeritus
Current Research and Scholarly Interests During the last five years, we have identified several small molecules that kill VHL deficient renal cancer cells through a synthetic lethal screening approach. Another major interest of my laboratory is in identifying hypoxia-induced genes involved in invasion and metastases. We are also investigating how hypoxia regulates gene expression epigenetically.
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Carlos A. Origel Marmolejo
Postdoctoral Research Fellow, Radiation Biology
Current Research and Scholarly Interests Research focused on elucidating the mechanism of DNA repair in cells.
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Jinglong Wang
Postdoctoral Research Fellow, Radiation Biology
Bio Jinglong was trained in a single-molecule lab in Institute Jacques Monod and École Normale Supérieure Paris and obtained his PhD degree from University of Paris in 2019, France. He dissected the molecular machinery of human and bacterial Non-homologous end joining, and interrogated the mechanism of SpCas9 plasticity on targeting DNA with deviant PAMs using single-molecule nanomanipulation tools. Jinglong joined the Frock lab in Jan 2020, and he is working on DSB-related chromosome topological changes and genomic interactions.
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Mengxiong Wang
Postdoctoral Research Fellow, Radiation Biology
Current Research and Scholarly Interests 1. To investigate the role of p53 in regulating the regression of lung adenocarcinoma and tumor microenvironment.
2. To determine synthetic lethal partner for p53 mutations in the context of lung adenocarcinoma. -
Jiangbin Ye
Assistant Professor of Radiation Oncology
Current Research and Scholarly Interests One hallmark of cancer is that malignant cells modulate metabolic pathways to promote cancer progression. My professional interest is to investigate the causes and consequences of the abnormal metabolic phenotypes of cancer cells in response to microenvironmental stresses such as hypoxia and nutrient deprivation, with the prospect that therapeutic approaches might be developed to target these metabolic pathways to improve cancer treatment.
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