School of Medicine
Showing 1-20 of 91 Results
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Vincent Michael Alford
Postdoctoral Research Fellow, Stem Cell Biology and Regenerative Medicine
Current Research and Scholarly Interests Identifying mechanisms by which the tumor microenvironment contributes to fundamental cellular signaling pathways responsible for regulating cancer stem cells' ability to self-renewal and promote tumor relapse in patients.
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Ash A. Alizadeh, MD/PhD
Associate Professor of Medicine (Oncology)
Current Research and Scholarly Interests My research is focused on attaining a better understanding of the initiation, maintenance, and progression of tumors, and their response to current therapies toward improving future treatment strategies. In this effort, I employ tools from functional genomics, computational biology, molecular genetics, and mouse models.
Clinically, I specialize in the care of patients with lymphomas, working on translating our findings in prospective cancer clinical trials. -
Philip Beachy
The Ernest and Amelia Gallo Professor in the School of Medicine, Professor of Developmental Biology and, by courtesy, of Chemical and Systems Biology
Current Research and Scholarly Interests Function of Hedgehog proteins and other extracellular signals in morphogenesis (pattern formation), in injury repair and regeneration (pattern maintenance). We study how the distribution of such signals is regulated in tissues, how cells perceive and respond to distinct concentrations of signals, and how such signaling pathways arose in evolution. We also study the normal roles of such signals in stem-cell physiology and their abnormal roles in the formation and expansion of cancer stem cells.
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Jamie Brett
MD Student, expected graduation Spring 2018
Current Research and Scholarly Interests Aging reversal in stem cells, DNA methylation, skeletal muscle repair
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Jacob Chabon
Ph.D. Student in Stem Cell Biology and Regenerative Medicine, admitted Autumn 2013
Current Research and Scholarly Interests I am interested in translational cancer research and bioinformatics, with a focus on using cancer genomics to inform more personalized treatment strategies for cancer patients. My lab uses cell free DNA (cfDNA), which is accessible via the circulation, as a non-invasive biomarker to detect and characterize how the genetic landscape of cancer patient?s tumors change over time. I am particularly interested in the mechanisms underlying acquired resistance to genotype-targeted therapies.
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Michael F. Clarke, M.D.
Karel H. and Avice N. Beekhuis Professor in Cancer Biology
Current Research and Scholarly Interests Dr. Clarke maintains a laboratory focused on two areas of research: i) the control of self-renewal of normal stem cells and diseases such as cancer and hereditary diseases; and ii) the identification and characterization of cancer stem cells. His laboratory is investigating how perturbations of stem cell regulatory machinery contributes to human disease. In particular, the laboratory is investigating epigenetic regulators of self renewal, the process by which stem cells regenerate themselves.