School of Medicine
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Amy Ladd, MD
Professor of Orthopaedic Surgery (Hand Surgery) and, by courtesy, of Medicine (Immunology & Rheumatology) at the Stanford University Medical Center
Current Research and Scholarly Interests Research Interests
1. The kinematics and forces associated with thumb carpometcarpal (CMC) function and pathology
2. The anatomy, microstructure, and immunofluorescent characteristics of the thumb CMC joint
3. Pathomechaniics of CMC arthritis: biomechanical wear, injury, genetic, and environmental causes
4. Archiving, vitalizing, and innovating medical and surgical knowledge, most recently with innovative iBook monographs
Basic Life Sci Reseach Associate, Orthopaedic Surgery
Bio Jieun Lee, PhD is a research associate in the Orthopaedic Surgery Department at Stanford University School of Medicine.
Dr. Lee earned her PhD degree at Yonsei University in Seoul, Korea. In her most significant scientific accomplishments as a PhD student, she elucidated the therapeutic potential of pancreatic progenitor cells, demonstrating how GLP-1-expressing adult pancreatic precursor cells reverse diabetes in STZ-induced diabetic rats (Lee et al., Stem Cells and Development 2009).
Dr. Lee continued stem cell research as a postdoctoral fellow at Stanford University where she lead a project generating safe and efficient human inducible pluripotent stem cells (iPSCs) from somatic cells (Yang et al., Protein Expression Purification, 2011 and Yang et al., Biotechnology Bioengineering, 2009) in John Cooke?s lab in the Department of Cardiovascular Medicine. In her most significant scientific accomplishments as a postdoc, firstly, she found the activation of innate immunity via Toll-like receptor 3 (TLR3) is required for nuclear reprogramming (Lee et al., Cell 2012). It was the first discovery to provide insight on the role of inflammatory mechanism in reprogramming, which has subsequently applied this mechanism to convert human fibroblasts into functional endothelial cells by activating TLR3 (Sayed et al., Circulation 2014).
Currently in Nidhi Bhutani's lab in the Department of Orthopaedic Surgery at Stanford, Dr. Lee has developed an efficient and well-defined chondrogenic differentiation protocol from human iPSCs to generate cartilage tissue in perspective of clinical application for Osteoarthritis (OA) patients and focal cartilage defects (Lee et al., The FASEB J 2015).
Joshua Levin, MD
Clinical Assistant Professor, Orthopaedic Surgery
Bio Dr. Levin completed a residency in physical medicine and rehabilitation at the University of Michigan in 2007, and a pain medicine fellowship at the Virginia Commonwealth University in 2008. Currently, he is a member of both the departments of orthopedic surgery and neurosurgery at Stanford University, where he also is the director of the PM&R interventional spine fellowship.
David Lowenberg, MD
Clinical Professor, Orthopaedic Surgery
Current Research and Scholarly Interests Dr. Lowenberg is a Past President of the Limb Lengthening and Reconstruction Society of North America. His clinical and research interests are in the treatment of nonunions and malunions with or without accompanying osteomyelitis and infection. He is well-published in the field of limb salvage and treatment of devastating limb injuries. He has ongoing research in limb transplantation via immunotolerance as well as biomechanics.