School of Medicine


Showing 1-20 of 678 Results

  • Marwa Abu El Haija

    Marwa Abu El Haija

    Clinical Assistant Professor, Pediatrics - Gastroenterology

    Bio I am a pediatric gastroenterologist with clinical and research interest in childhood obesity. I believe that each patient is unique in their disease and background, that is why they deserve to be approached in an individualized way. I aspire to discover what's unknown about the pathophysiologic causes of obesity, and the mechanisms of which treatments work. My clinical and research interests in pediatric obesity found home within Stanford's distinctive position academically, medically and geographically.

  • Janelle Aby

    Janelle Aby

    Clinical Professor, Pediatrics - General Pediatrics

    Current Research and Scholarly Interests My interest is in the care and evaluation of newborns. In particular, I have been focusing on improving the educational experience for our residents and students in the nursery regarding the examination and management of term or near-term infants.

  • Maya Adam

    Maya Adam

    Clinical Assistant Professor, Pediatrics - Infectious Diseases

    Bio Dr. Adam is the Director of Health Media Innovation and a Clinical Assistant Professor in the Department of Pediatrics at Stanford School of Medicine. She creates video-based entertainment-education on topics related to maternal child health, nutrition and disease prevention. She has designed and produced online educational content for the Stanford School of Medicine for use in their preclinical programs, continuing medical education programs and global health promotion efforts. She is the creator of five massive open online courses and advisor for Stanford?s Digital Medical Education International Collaborative (Digital MEdIC) in South Africa. Adam is principal investigator on two randomized
    controlled trials investigating the impact of digital global health education interventions on health-promoting behaviors. She is also a Faculty Fellow at the Center for Innovation in Global Health and the author of Food, Love, Family: A Practical Guide to Child Nutrition.

  • Ananta Addala

    Ananta Addala

    Instructor, Pediatrics - Endocrinology and Diabetes

    Bio I am a physician scientist addressing disparities in type 1 diabetes (T1D) management and outcomes. My research interests are at the intersection of T1D and inequities evaluating system-level and individual-level contributors to T1D disparities. My longstanding research and clinical interests are to promote equitable care for youth with T1D informed by the biological, social, psychological, and systemic determinants of health.

  • Catherine Aftandilian

    Catherine Aftandilian

    Clinical Assistant Professor, Pediatrics - Hematology & Oncology

    Current Research and Scholarly Interests I am interested in the prevention and management of infectious complication in pediatric oncology patients. I am also interested in developing a protocol for the management of low risk patients with fever and neutropenia.

  • Rajni Agarwal-Hashmi

    Rajni Agarwal-Hashmi

    Associate Professor of Pediatrics (Stem Cell Transplantation) at the Lucile Salter Packard Children's Hospital

    Current Research and Scholarly Interests Hematopoietic Stem cell biology-created a SCID mouse model to study engraftment of cord blood derived hematopoietic cells and use of this model to develop gene transfer technology for Fanconi anemia.
    Clinical research interests are to develop new protocols to reduce graft vs host disease,treatment of viral infections post transplant and use of manipulated HSC graft in patients who receive mismatched donor transplants.

  • Steven R. Alexander, MD

    Steven R. Alexander, MD

    Professor of Pediatrics (Nephrology) at the Lucile Salter Packard Children's Hospital

    Current Research and Scholarly Interests Dialysis, kidney transplantation, continuous renal replacement therapy in pediatric patients; chronic kidney disease in pediatric patients.

  • Leina Alrabadi

    Leina Alrabadi

    Clinical Assistant Professor, Pediatrics - Gastroenterology

    Bio I enjoy working with a multidisciplinary team to care for patients who have complex medical needs with the aim of giving children a better future. As a clinical researcher, my main focus is on finding improved therapies for autoimmune and cholestatic liver diseases, since an ideal therapy currently does not exist.

  • Cristina M. Alvira

    Cristina M. Alvira

    Associate Professor of Pediatrics (Critical Care) at the Stanford University Medical Center

    Current Research and Scholarly Interests The overall objective of the Alvira Laboratory is to elucidate the mechanisms that promote postnatal lung development and repair, by focusing on three main scientific goals: (i) identification of the signaling pathways that direct the transition between the saccular and alveolar stages of lung development; (ii) exploration of the interplay between postnatal vascular and alveolar development; and (iii) determination of developmentally regulated pathways that mediate lung repair after injury.

  • Manuel R. Amieva

    Manuel R. Amieva

    Professor of Pediatrics (Infectious Diseases) and of Microbiology and Immunology

    Current Research and Scholarly Interests My laboratory studies how bacteria colonize our bodies for long periods of time, and how interactions between bacteria and the epithelial surfaces of the gastrointestinal tract and skin may lead to disease. Epithelial surfaces are the first barrier against infection, but they also where our bodies meet and co-evolve with the microbial world.. Several of our studies have focused on the epithelial junctions as a target for bacterial pathogens. The host epithelium uses its epithelial junctions to form a tight but dynamic barrier with an external surface that is inhospitable to microbial attachment, secretes anti-microbial compounds, and has a rapid rate of self-renewal. The balance in the microbe-epithelial relationship results in silent commensalism or symbiosis; an imbalance results in diseases ranging from acute bacterial invasive disease to chronic ulcers or carcinoma.

    Our laboratory has developed novel microscopy applications such as quantitative 3D confocal microscopy, electron microscopy, time-lapse imaging, microinjection and micromanipulation to visualize the interaction of pathogens with epithelial cells in culture and in animal and human tissues. Many of out studies focus on the gastric pathogen Helicobacter pylori, but we have also expanded our investigations to include the intestinal pathogens Listeria monocytogenes and Salmonella enterica, and the skin pathogen and colonizer Staphylococcus aureus. I believe that elucidating how microbes communicate with and alter our epithelial cells at a molecular level will be important for finding novel therapeutic targets to control mucosal colonization and prevent invasive disease.

    Using this perspective, we have uncovered several novel concepts of how bacteria colonize and breach our epithelial surfaces. For example, we discovered that Helicobacter pylori target the intercellular junctions, and in particular that the virulence factor CagA affects junction assembly and cell polarity. This confers H. pylori the ability to extract nutrients and grow directly on the epithelial surface. We also found that these properties of CagA have consequences for cellular transformation of the epithelium. For instance, we showed that H. pylori affect the activity and state of epithelial stem cells in the stomach by colonizing the epithelial surface deep in the gastric glands. This gland-associated population is essential for pathological inflammation and hyperplasia in animal models, and confers significant colonization advantages to the bacteria. Our Listeria research uncovered a new mechanism and site where bacteria can breach the gastrointestinal epithelial barrier to invade. We found that Listeria find their receptor for invasion at sites of epithelial senescence, where the epithelial junctions undergo dynamic turnover. To study Salmonella and H. pylori we have developed a human organoid model to study their interactions with human gut epithelium in vitro. To study Staphylococcus aureus pathogenesis, we have developed methods to visualize infection at the scale of a single bacterial microcolony using an organoid culture system of human keratinocytes and fibroblasts that grow into a 3D skin-equivalent. We recently identified several proteins at the eptithelial junctions as host factors involved in the pathogenesis of one of Staphylococcus aureus major toxins.

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