School of Medicine
Showing 21-40 of 260 Results
Clinical Professor, Anesthesiology, Perioperative and Pain Medicine
Current Research and Scholarly Interests Pediatric Cardiac Anesthesia
Adult Congenital Heart Disease
Associate Professor of Chemistry and Senior Fellow at the Precourt Institute for Energy
Bio Associate Professor of Chemistry Matthew Kanan develops new catalysts and chemical reactions for applications in renewable energy conversion and CO2 utilization. His group at Stanford University has recently developed a novel method to create plastic from carbon dioxide and inedible plant material rather than petroleum products, and pioneered the study of ?defect-rich? heterogeneous electro-catalysts for converting carbon dioxide and carbon monoxide to liquid fuel.
Matthew Kanan completed undergraduate study in chemistry at Rice University (B.A. 2000 Summa Cum Laude, Phi Beta Kappa). During doctoral research in organic chemistry at Harvard University (Ph.D. 2005), he developed a novel method for using DNA to discover new chemical reactions. He then moved into inorganic chemistry for his postdoctoral studies as a National Institutes of Health Postdoctoral Research Fellow at the Massachusetts Institute of Technology, where he discovered a water oxidation catalyst that operates in neutral water. He joined the Stanford Chemistry Department faculty in 2009 to continue research into energy-related catalysis and reactions. His research and teaching have already been recognized in selection as one of Chemistry & Engineering News? first annual Talented 12, the Camille Dreyfus Teacher-Scholar Award, Eli Lilly New Faculty Award, and recognition as a Camille and Henry Dreyfus Environmental Mentor, among other honors.
The Kanan Lab addresses fundamental challenges in catalysis and synthesis with an emphasis on enabling new technologies for scalable CO2 utilization. The interdisciplinary effort spans organic synthesis, materials chemistry and electrochemistry.
One of the greatest challenges of the 21st century is to transition to an energy economy with ultra-low greenhouse gas emissions without compromising quality of life for a growing population. The Kanan Lab aims to help enable this transition by developing catalysts and chemical reactions that recycle CO2 into fuels and commodity chemicals using renewable energy sources. To be implemented on a substantial scale, these methods must ultimately be competitive with fossil fuels and petrochemicals. With this requirement in mind, the group focuses on the fundamental chemical challenge of making carbon?carbon (C?C) bonds because multi-carbon compounds have higher energy density, greater value, and more diverse applications that one-carbon compounds. Both electrochemical and chemical methods are being pursued. For electrochemical conversion, the group studies how defects known as grain boundaries can be exploited to improve CO2/CO electro-reduction catalysis. Recent work has unveiled quantitative correlations between grain boundaries and catalytic activity, establishing a new design principle for electrocatalysis, and developed grain boundary-rich copper catalysts with unparalleled activity for converting carbon monoxide to liquid fuel. For chemical CO2 conversion, the group is developing C?H carboxylation and CO2 hydrogenation reactions that are promoted by simple carbonate salts. These reactions provide a way to make C?C bonds between un-activated substrates and CO2 without resorting to energy-intensive and hazardous reagents. Among numerous applications, carbonate-promoted carboxylation enables the synthesis of a monomer used to make polyester plastic from CO2 and a feedstock derived from agricultural waste.
In addition to CO2 chemistry, the Kanan group is pursuing new strategies to control selectivity in molecular catalysis for fine chemical synthesis. Of particular interest in the use of electrostatic interactions to discriminate between competing reaction pathways based on their charge distributions. This effort uses ion pairing or interfaces to control the local electrostatic environment in which a reaction takes place. The group has recently shown that local electric fields can control regioselectivity in isomerization reactions catalyzed by gold complexes.
Chia Sui Kao
Assistant Professor of Pathology at the Stanford University Medical Center
Current Research and Scholarly Interests Genitourinary tumors with a special interest in Testicular tumors
Ming Jeffrey Kao, PhD, MD
Clinical Assistant Professor, Orthopaedic Surgery
Current Research and Scholarly Interests 1. Patient-reported outcomes. Efficient, multi-feature item-response theory (IRT) based computerized adaptive testing (CAT) algorithm using item banks from PROMIS and NIH Toolbox
2. Activity monitoring. Novel analytic framework for physical activity monitoring in the context of pain.
3. Operations research. Multi-variable discrete and continuous optimization for Lean Hospital Management
4. National trends in pain medication prescription
Associate Professor of Medicine (Pulmonary and Critical Care Medicine)
Current Research and Scholarly Interests Our research program has several active projects:
1.) Pulmonary Vascular Disease – Simvastatin reversed experimental pulmonary hypertension, and is safe for treatment of patients. Blinded clinical trials of efficacy are in progress.
2.) Lung inflammation and regeneration (stem cells)
3.) Lung surfactant rheology and oxidative stress
4.) Gene regulation by RNA binding proteins, NF45 and NF90 through transcriptional and posttranscriptional mechanisms
Michael S. Kapiloff, MD, PhD
Associate Professor (Research) of Ophthalmology and, by courtesy, of Medicine (Cardiovascular Medicine)
Current Research and Scholarly Interests Dr. Michael S. Kapiloff is a faculty member in the Departments of Ophthalmology and Medicine (Cardiovascular Medicine) and a member of the Stanford Cardiovascular Institute. Although Dr. Kapiloff was at one time a Board-Certified General Pediatrician, he is currently involved in full-time basic science and translational research. His laboratory studies the basic molecular mechanisms underlying the response of the retinal ganglion cell and cardiac myocyte to disease. The longstanding interest of his laboratory is the role in intracellular signal transduction of multimolecular complexes organized by scaffold proteins. Recently, his lab has also been involved in the translation of these concepts into new therapies, including the development of new AAV gene therapy biologics for the prevention and treatment of heart failure and for neuroprotection in the eye.
URL to NCBI listing of all published works:
For more information see Dr. Kapiloff's lab website: http://med.stanford.edu/kapilofflab.html
Clinical Instructor, Psychiatry and Behavioral Sciences
Current Research and Scholarly Interests Dr. Kaplan's research interests span four (often overlapping) domains: (1) pathophysiologic aspects of insomnia and hypersomnia in mood disorders, including mechanisms, correlates, and sequelae of these sleep disturbances; (2) behavioral interventions for sleep disturbances in adults and adolescents; (3) circadian and psychosocial factors impacting sleep in adolescence; and (4) machine learning approaches to big data.
Michael J. Kaplan, MD
Professor of Otolaryngology - Head and Neck Surgery at the Stanford University Medical Center, Emeritus
Current Research and Scholarly Interests 1) New therapeutic approaches for head and neck cancer, including immune stimulation possibilities (IRX-2 protocol), integration of biological modifiers, and, eventually, genetic approaches.
2) Head and neck cancer stem cells: identification, characterization, control--in conjunction with the Irv Weissman and Michael Clarke labs in the Stem Cell Institute
3) Development of innovative surgical methods at the anterior cranial base
Adjunct Professor, Medicine - Primary Care and Population Health
Current Research and Scholarly Interests Health services research
Studies on the cost and quality of health care
Health outcome measurement
Social determinants of health