School of Medicine
Showing 1-10 of 49 Results
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Edward Esplin
Postdoctoral Medical fellow, Genetics
Current Research and Scholarly Interests Familial adenomatous polyposis (FAP), a heritable colon cancer syndrome, causes colorectal adenocarcinoma (CRC) in children as young as 9 years, and confers 100% lifetime risk of CRC. FAP patient CRCs have accumulation of alterations in multiple tumor suppressors (i.e. Kras, p53), which accumulate due to the initial APC mutation. We hypothesize that there is a reproducible cascade of molecular changes in FAP that lead to CRC and will test this using genomic and transcriptomic technologies.
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Shanil Ebrahim
Postdoctoral Research fellow, SCRDP/ Heart Disease Prevention
Bio Dr. Shanil Ebrahim specializes in clinical epidemiology, meta-analytic methods, insurance medicine, disability management, and mental health issues in the workplace. His primary methodological focus is in the evaluation of re-analyses and secondary analyses of randomized trials, addressing the impact of missing participant data in meta-analyses, multilevel regression modeling, and multiple treatment comparison models. His primary focus in insurance medicine is in determining optimal management and evaluating predictors of recovery in patients receiving disability benefits, and systematically evaluating the evidence of independent medical evaluations. For his doctoral work, Dr. Ebrahim developed the first rigorous approach to address missing participant data for continuous outcomes in systematic reviews.
Dr. Ebrahim has authored numerous publications in high impact peer-reviewed journals including JAMA, CMAJ, Journal of Clinical Epidemiology, PLoS ONE, BMJ Open, Chest, Clinical Pharmacology & Therapeutics, and Journal of Public Health Policy. For his academic efforts, Dr. Ebrahim has received numerous scholarships including the Canadian Institutes of Health Research Fellowship and Doctoral, and the MITACS Elevate and Accelerate awards.
