School of Medicine
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Instructor, Pediatrics - Stem Cell Transplantation
Bio Dr. Cepika is an immunologist with an extensive background in translational research, autoimmunity, autoinflammation, and human systems immunology. Her goal is to understand the mechanisms governing immunological tolerance, and to leverage this knowledge to cure currently incurable diseases.
Dr. Cepika received her MD degree and a PhD in Immunology from the University of Zagreb School of Medicine in Croatia. There, she focused on the immunomonitoring of patients with lupus, identifying how circulating DNA levels changed with therapy. Subsequently, she joined the lab of Dr. Virginia Pascual at the Baylor Institute for Immunology Research in Dallas, Texas. Dr. Pascual had previously discovered that IL-1beta is a key pathogenic player in systemic juvenile idiopathic arthritis (sJIA), but the immune alterations contributing to IL-1beta-mediated inflammation remained unknown. To address this, Dr. Cepika developed a 3D in vitro stimulation assay to evaluate immune responses of blood leukocytes of pediatric sJIA patients. In combination with integrated bioinformatics analysis, this approach identified aberrant cellular responses, transcriptional pathways and genes that shed new light on immune dysregulation in sJIA. This assay can be further applied to dissect underlying immunopathogenic mechanisms in many human disorders.
Currently, Dr. Cepika is a member of the laboratory of Dr. Maria Grazia Roncarolo, in the Pediatric Division of Stem Cell Biology and Regenerative Medicine at Stanford University School of Medicine. There, she is working to uncover the underlying mechanisms governing type 1 regulatory T (Tr1) cell differentiation and function, and use this knowledge to design Tr1 cell-based therapies for hematopoietic stem cell transplantation, cancer immunotherapy and autoimmunity.
Lisa J. Chamberlain
Professor of Pediatrics (General Pediatrics) at the Lucile Salter Packard Children's Hospital
Current Research and Scholarly Interests Child Health disparities - Projects focus on elucidating the non-clinical factors that impact access to appropriate care for children with chronic illness.
Health Policy - Projects explore the intersection of medicine as a profession and formation of child health policy.
Anne Lynn S. Chang, MD
Professor of Dermatology at the Stanford University Medical Center
Current Research and Scholarly Interests I have two main research interests:
1) to better understand and treat patients with aggressive basal and squamous cell carcinomas
2) to better understand the genetic and epigenetic mechanisms of healthy human skin aging and to translate these insights into better care of skin diseases enriched in older patients particularly skin cancer and rosacea
Howard Y. Chang, MD, PhD
Virginia and D. K. Ludwig Professor of Cancer Research and Professor of Genetics
Current Research and Scholarly Interests Our research is focused on how the activities of hundreds or even thousands of genes (gene parties) are coordinated to achieve biological meaning. We have pioneered methods to predict, dissect, and control large-scale gene regulatory programs; these methods have provided insights into human development, cancer, and aging.
Assistant Professor of Surgery (Pediatric Surgery) at the Stanford University Medical Center
Current Research and Scholarly Interests Dr. Chao's research focuses on preventing surgical diseases minimizing the impact of surgery. She works with the Asian Liver Center towards the global eradication of hepatitis B, the leading cause of liver cancer and liver disease globally. Dr. Chao helped launch the Jade Ribbon Campaign in 2001 to improve public and physician awareness about hepatitis B. Dr. Chao also serves as the Trauma Medical Director of LPCH and is interested in preventing pediatric traumatic injuries.
Assistant Professor of Anesthesiology, Perioperative and Pain Medicine (Pediatric) at the Stanford University Medical Center
Current Research and Scholarly Interests Dr. Char's research is focused on identifying and addressing ethical concerns associated with the implementation of next generation technologies like whole genome sequencing and its attendant technologies like machine learning to bedside clinical care.
Bertha Chen, MD
Professor of Obstetrics and Gynecology (Gynecology - Urogynecology) and, by courtesy, of Urology at the Stanford University Medical Center
Current Research and Scholarly Interests Dr. Chen?s research examines the molecular causes of urinary incontinence and pelvic floor dysfunction. Recognizing that urinary incontinence linked to demise of smooth muscle sphincter function, she is investigating the potential use of stem cell regeneration to restore muscle capacity.
James K. Chen
Jauch Professor and Professor of Chemical and Systems Biology, of Developmental Biology and of Chemistry
Current Research and Scholarly Interests Our laboratory combines chemistry and developmental biology to investigate the molecular events that regulate embryonic patterning, tissue regeneration, and tumorigenesis. We are currently using genetic and small-molecule approaches to study the molecular mechanisms of Hedgehog signaling, and we are developing chemical technologies to perturb and observe the genetic programs that underlie vertebrate development.