Paul C. Grimm

Professor of Pediatrics (Nephrology)

Clinical Focus

Pediatric Nephrology
pediatric renal transplantation
Cystinosis

Academic Appointments

Professor - University Medical Line, Pediatrics - Nephrology
Member, Maternal & Child Health Research Institute (MCHRI)

Administrative Appointments

Pediatric Nephrology Fellowship Director, LPCH at Stanford (2007 - Present)
Medical Director of Cystinosis Clinlc, LPCH at Stanford (2011 - Present)
Medical Director of Pediatric Kidney Transplant Program, LPCH at Stanford (2012 - Present)

Honors & Awards

Member, American Board of Pediatrics-Pediatric Nephrology Subboard (2010-2018)

Boards, Advisory Committees, Professional Organizations

Scientific Advisory Board Member, Cystinosis Research Foundation (2016 - Present)
Board Member, Improve Renal Outcomes Collaborative (2021 - Present)

Professional Education

Board Certification: American Board of Pediatrics, Pediatric Nephrology (2020)
Medical Education: University of Saskatchewan College of Medicine (1981) Canada
Fellowship: Dalhousie University Residency Training (1988) Canada
Residency: Winnipeg Children's Hospital (1986) Canada
Residency: Dalhousie University (1985) Canada
Fellowship: UCLA Health Sciences (1991) CA
Internship: University of Saskatchewan (1982) Canada
Fellowship, UCLA, Pediatric Transplant Immunology (1991)
Fellowship, Dalhousie University, Halifax, Pediatric Nephrology (1988)
Pediatric Residency, University of Manitoba, Pediatrics Yr III (1986)
Pediatric Residency, Dalhousie University, Halifax, Pediatrics I & II (1985)
Interneship, U. of Saskatchewan, Rotating Interne (1982)
MD with Distinction, University of Saskatchewan, Medicine (1981)

Contact

Academic pgrimm@stanford.edu Tel: (650) 723-7903 Fax: (650) 498-6714

Alternate Contact Kim Sands Admin. Pediatric Nephrology ksands@stanford.edu Tel: 650-723-7903

Clinical (Primary)

This is the primary clinic for this clinical provider. For additional clinical locations and information, please visit the link(s) listed below in the 'Additional Clinical Info' section.

Pediatric Nephrology Clinic 770 Welch Rd Ste 300 Palo Alto CA 94304 Tel: (650) 724-0353 Fax: (650) 721-6685

Additional Clinical Info

Stanford Medicine Children's Health

Current Research and Scholarly Interests

Computerized image analysis of kidney and liver biopsies to quantitate and diagnose subtle changes in tissue structure.
Renal Inflammation
Renal Allograft Rejection
Renal Fibrosis in;
-Primary Kidney Disease
-Transplant Kidney Disease
Liver fibrosis
Steatohepatitis

Clinical Trials

Early Trial of Allogeneic Hematopoietic Stem Cell Transplantation for Patients Who Will Receive a Kidney Transplant From the Same Donor Recruiting
More
This is a single center, non-randomized, non-controlled open-label phase 1b/2a trial of performing sequential αβdepleted-HSCT and KT in patients requiring KT to prevent kidney rejection post-KT, in the absence of any post-KT immunosuppression, to abrogate the need for lifelong immunosuppression, the risk of chronic rejection and, ultimately, the need for repeated transplantation.
Lead Sponsor
Stanford Investigators
View full details
The Effect of Exercise on Muscle Dysfunction in Cystinosis Recruiting
More
Classification of activity tolerance is of importance in chronic progressive myopathies, not only to better understand functional implications of the disease state itself, but also for purposes of exercise prescription for health maintenance. Maximal exercise testing has been considered as the gold standard of assessing maximal aerobic capacity, however testing in individuals with neuromuscular disease is often limited due to pain, activity intolerance, musculoskeletal impairments, fatigue and other such related variables. Often, submaximal exercise testing can overcome some of these obstacles, and as such, is used frequently in the clinical environment. Non-ambulatory exercise testing utilizing an arm ergometer specifically has not been studied as heavily, especially in those with progressive myopathies. For this study, we will use maximal aerobic capacity testing for individuals with Cystinosis Myopathy utilizing a bike ergometer to allow testing of individuals regardless of their ambulatory status.

Lead Sponsor
- Stanford University
Stanford Investigators
View full details
Pharmacokinetics, Safety and Tolerability of Single-dose Belatacept in Adolescent Kidney Transplant Recipients Not Recruiting
More
The purpose of this study is to evaluate how well adolescent kidney transplant patients tolerate a single dose of belatacept they receive at least 6 months after transplant surgery, and how their body handles the drug.

Stanford is currently not accepting patients for this trial. For more information, please contact Paul Grimm, Site 0006, 650-725-5295.
Lead Sponsor
Stanford Investigators
- Paul C. Grimm
View full details
Perioperative Aminophylline to Improve Early Kidney Function After a Kidney Transplant Not Recruiting
More
The aim of this study is to evaluate whether peri-transplant administration of a drug named aminophylline to children undergoing a kidney transplant from deceased donors improves early graft function and also projects on long term graft function.

Stanford is currently not accepting patients for this trial. For more information, please contact Vivian Shih, MD, 650-723-7903.

Lead Sponsor
- Stanford University
Stanford Investigators
- Paul C. Grimm
View full details

2024-25 Courses

Independent Studies
- Directed Reading in Pediatrics
  PEDS 299 (Aut, Win, Spr)
- Early Clinical Experience
  PEDS 280 (Aut, Win, Spr)
- Graduate Research
  PEDS 399 (Aut, Win, Spr)
- Medical Scholars Research
  PEDS 370 (Aut, Win, Spr)
- Undergraduate Directed Reading/Research
  PEDS 199 (Aut, Win, Spr)

All Publications

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Steven R. Alexander, MD

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Nephrology (Kidney), Pediatric, Pediatric Nephrology, Dialysis, Kidney Transplantation, Continuous Renal Replacement Therapies, Hypertension, Acute and Chronic Kidney Failure
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Stephan Busque

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My research interest is focused on the improvement of clinical immunosuppression. I am involved in the evaluation of new immunosuppressive drugs, potentially more efficacious or less toxic. My ultimate goal is to achieve tolerance, a state that would obviate the need for any drugs. I am an investigator part of a multidisciplinary tolerance induction project using total lymphoid irradiation and donor hematopoietic stem cells infusion after living donor kidney transplantation.

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Kenneth L. Cox

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Carlos O. Esquivel, M.D., Ph.D.,FACS

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Purvesh Khatri

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