Robert K. Le?niak joined the Medicinal Chemistry Knowledge Center at Stanford ChEM-H in 2018 as a postdoctoral fellow. Prior to coming to Stanford, he worked with Professor Chris Schofield at the University of Oxford, as a postdoctoral research associate, designing novel antibiotics for the European gram-negative antibacterial engine (ENABLE) and UK Medical Research Council (MRC). Dr Le?niak also completed his DPhil under the guidance of Professor Schofield as a BHF-CRE studentship recipient, which involved the design and implementation of small molecules targeting Fe(II), 2-oxoglutarate dependent oxygenase enzymes involved in carnitine biosynthesis and hypoxic response as a means to treat cardiovascular disease. In addition, work on small-molecule modulation of bacterial metallo-beta-lactamases to combat antibiotic resistance was also carried out. Dr Le?niak completed his undergraduate at the University of Bristol, and worked at GlaxoSmithKline, North Carolina, developing inhibitors of bromodomains and histone acetyl-transferases. He is currently working with Professor Thomas Montine at the Stanford School of Medicine on the design of neurotransmitter prodrugs.
MSci, University of Bristol, MSci in Chemistry (2012)
DPhil, Oxford University, Chemical Biology (2017)