Current Research and Scholarly Interests
Saiful has completed his PhD at the Molecular Neurobiology division in the Department of Medical Biochemistry and Biophysics of the Karolinska Institutet, Sweden. He has a strong background in molecular biology and is highly experienced in method development. Single-cell transcriptomics is his key area of interest. Saiful developed two methods in the single-cell field; Single-cell Tagged Reverse Transcription (STRT) and molecule counting at single cell level using Unique Molecular Identifier (UMI). One of the goals of his research is to identify the cell types in a complex tissue ? a fundamental question in cell biology. In his postdoctoral work at Stanford, Saiful is applying single cell transcriptomics methods to the field of immunological self-tolerance in human. In addition, Saiful is also involved in screening for chemical and genetic strategies to improve a rare genetic disease caused by a defect in N-glycanase and associated with abnormal accumulation of misfolded glycoproteins.