School of Medicine
Showing 101-200 of 301 Results
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John Gorzynski
Postdoctoral Research Fellow, Genetics
Bio Veterinarian and Researcher with a keen interest in genetic determinants of cardiomyopathies in great apes
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Henry T. (Hank) Greely
Deane F. and Kate Edelman Johnson Professor of Law and, Professor, by courtesy, of Genetics
Current Research and Scholarly Interests Since 1992 my work has concentrated on ethical, legal, and social issues in the biosciences. I am particularly active on issues arising from neuroscience, human genetics, and stem cell research, with cross-cutting interests in human research protections, human biological enhancement, and the future of human reproduction.
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William Greenleaf
Associate Professor of Genetics and, by courtesy, of Applied Physics
Current Research and Scholarly Interests Our lab focuses on developing methods to probe both the structure and function of molecules encoded by the genome, as well as the physical compaction and folding of the genome itself. Our efforts are split between building new tools to leverage the power of high-throughput sequencing technologies and cutting-edge optical microscopies, and bringing these technologies to bear against basic biological questions by linking DNA sequence, structure, and function.
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Tuhin Guha
Postdoctoral Research Fellow, Genetics
Bio A research individual with more than ten years of extensive research experience in molecular biology techniques ranging from DNA/RNA manipulations, recombinant protein expression, purification, and biochemical characterization of DNA-cutting enzymes, needed for genetic engineering. I am a postdoctoral research fellow in the Department of Genetics, Stanford University. I work with Dr. Mike Snyder. My research involves multiplexed-molecular imaging for the precancerous and cancerous colon polyps (Familial adenomatous polyposis) using a cutting-edge technology, Codex. My previous work involved novel gene therapy approaches to cure muscle disorders, particularly Limb-girdle muscular dystrophy 2A using mouse models, and gene repair studies using modified CRISPR system through plasmid/protein-oligo based transfections, electroporation in human cells, microinjection in frog embryos and analyzing editing efficiencies using flow cytometry. I have a multi-disciplinary background, therefore I have a solid understanding and working knowledge in a broader domain within the biological sciences, be it from animal behavior, ecology, gene regulation, genetic diseases to understanding and designing ?molecular switches? within DNA-cutting proteins, such as meganucleases, and CRISPR/Cas9 for genome engineering. I have strong communication skills, presented my research in various conferences and published heavily in the field of DNA-cutting enzymes and their use as genome editing tools. I have a proven ability to manage challenging research objectives, collaborated with other research teams, and delivered results effectively. I always welcome new ideas and interact with people to learn any new skills and experiences. I have also supervised several undergraduate project students, summer students and junior graduate students. My mentorship to the lab colleagues have been very productive. While I am not working, I enjoy photography.
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Leonore A. Herzenberg
Department of Genetics Professor
Current Research and Scholarly Interests B-cell lineage development and function; IgH rearrangement and repertoire analysis; HSC and lymphoid stem cells and lineages in mouse and man; T cell regulation of antibody responses; glutathione regulation of lymphoid and myeloid subst functions; development of advanced methods and software for Fluorescence-Activated Cell Sorting (FACS) and related analyses.
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Albert Hinman
Ph.D. Student in Genetics, admitted Autumn 2015
Bio Albert is a Genetics PhD candidate in Dr. Anne Villeneuve's laboratory at Stanford University. His thesis work investigates the mechanisms underlying double-strand break initiation in meiotic recombination using genomic sequencing, fluorescence microscopy, molecular biology, nematode culturing, and classical genetics. Outside of lab, he devotes time to education, mentoring, diversity-advocacy, policy, and science outreach.
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Livnat Jerby
Assistant Professor of Genetics
Bio Livnat Jerby is an Assistant Professor of Genetics at Stanford University. Her research focuses on multicellular dynamics, as a disease driver and therapeutic avenue, particularly in the context of cancer immunology. In her work, she aims to identify the drivers, molecular underpinnings, and causal structure of multifactorial immune evasion mechanisms, and use this information to identify new and more effective ways to augment and unleash targeted immunity via combinatorial interventions. To address this challenge at scale, she develops integrative approaches, fusing single-cell sequencing and imaging with machine learning, genetic and environmental perturbations.
Thus far, her research provided new perspectives to key facets of tumor biology, encompassing metabolism, genetics, and immunology. As a postdoctoral fellow at the Broad Institute of MIT and Harvard, she identified regulators of T cell exclusion and dysfunction with Levi Garraway and Aviv Regev. She holds a B.Sc. in Computer Science and Biology and obtained her PhD in 2016 from Tel Aviv University, where she worked with Eytan Ruppin and developed new ways to interrogate cancer metabolism and genetics.
This fall Livnat joined Stanford Genetics to establish a multidisciplinary lab that will harness machine learning in combination with clinical data and extensive functional testing to dissect and target immune dysregulation in cancer, aiming to leverage the versatile, interconnected, and non-linear function of genes, cells, and tissues for disease detection, prevention, and treatment.
Her research has been generously supported by the Schmidt Family Foundation, Rothschild Foundation, the Cancer Research Institute (CRI), the Burroughs Wellcome Fund (BWF), and Chan Zuckerberg Biohub initiative. -
Nicholas Antonios Kalogriopoulos
Postdoctoral Research Fellow, Genetics
Bio Nick's broad research interests are in developing tools and technologies for research and therapeutic applications. Nick obtained a B.S. in Genetics and Molecular Biology from the University of Wisconsin-Madison. During his undergraduate career, he trained with Dr. Paul Sondel, where he worked on preclinical testing of novel immunotherapeutic agents for the treatment of neuroblastoma. He obtained a Ph.D. in Biomedical Science with Dr. Pradipta Ghosh, elucidating the structural basis of non-canonical G protein activation by a novel protein family of Guanine Nucleotide Exchange Modulators (GEMs). As a Postdoctoral Researcher with Professor Alice Ting at Stanford University, his current research focuses on developing a new system for programmable and user-controlled cellular behaviors for immuno-oncology applications.
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Saswati Karmakar
Postdoctoral Research Fellow, Genetics
Bio Saswati Karmakar obtained her undergraduate degree in Biotechnology at Guru Gobind Singh Indraprastha University, New Delhi. She pursued her Ph.D. in Biochemistry and Molecular Biology at the University of Nebraska Medical Center, Omaha, working on the molecular characterization of pancreatic cancer stem cells and their contribution to cancer initiation and progression. Then, she moved to Stanford University with the National Cancer Institute's F99/K00 award for a postdoctoral position in Monte Winslow's lab. Saswati's current research explores the role of tumor suppressor genes in pancreatic cancer pathogenesis.
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Mark A. Kay, M.D., Ph.D.
Dennis Farrey Family Professor in Pediatrics, and Professor of Genetics
Current Research and Scholarly Interests Mark A. Kay, M.D., Ph.D. Director of the Program in Human Gene Therapy and Professor in the Departments of Pediatrics and Genetics. Respected worldwide for his work in gene therapy for hemophilia, Dr. Kay and his laboratory focus on establishing the scientific principles and developing the technologies needed for achieving persistent and therapeutic levels of gene expression in vivo. The major disease models are hemophilia, hepatitis C, and hepatitis B viral infections.
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Christina Kim
Postdoctoral Research Fellow, Genetics
Current Research and Scholarly Interests Simultaneous recording and manipulation of neural activity:
I actively pursue the development and application of techniques for all-optical recording and manipulation of neural activity in living animals. During my PhD I developed a microscope capable of performing bulk calcium recording and optogenetic stimulation in freely moving animals (Frame-projected Independent-fiber Photometry). We demonstrated its utility by recording from sparse dopaminergic axon terminals distributed throughout the brain during rewarding versus aversive stimuli, and by recording from up to 7 different brain regions during a social interaction test. Using simultaneous optogenetics and calcium recording, we could then fine-tune the optogenetic stimulation of dopamine neurons to produce activity that mimicked the naturally-occurring response profiles during behavior. This work was published in Nature Methods, and has been patented and licensed to a company that has commercialized the microscope (www.neurophotometrics.com). -
Karla Kirkegaard
Violetta L. Horton Research Professor and Professor of Microbiology and Immunology
Current Research and Scholarly Interests The biochemistry of RNA-dependent RNA polymerase function, the cell biology of the membrane rearrangements induced by positive-strand RNA virus infection of human cells, and the genetics of RNA viruses, which, with their high error rates, live at the brink of error catastrophe, are investigated in the Kirkegaard laboratory.
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Anshul Kundaje
Assistant Professor of Genetics and of Computer Science
Current Research and Scholarly Interests We develop statistical and machine learning frameworks to learn predictive, dynamic and causal models of gene regulation from heterogeneous functional genomics data.
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Hayan Lee
Postdoctoral Research Fellow, Genetics
Bio I am a postdoctoral scholar at Genetics Department, Stanford University. Before I moved to Stanford, I served as a Simons postdoctoral fellow at Joint Genome Institute (JGI). I have earned my Ph.D. in Computer Science Department at Stony Brook University. My dissertation is about ?Algorithms and applications in genome assembly using long read sequencing technology?, advised by Prof. Michael Schatz, Simons Center for Quantitative Biology, Cold Spring Harbor Laboratory (CSHL). I received my Master?s degree from Carnegie Mellon University. The master thesis was published at 70th IEEE Vehicular Technology Conference. My undergraduate degree with Cum Laude was received at Seoul National University in Korea and worked for 4 years at AhnLab, Inc., where I programmed Windows kernel-level file system filter driver for V3 anti-virus program.
I am interested in developing methods (tools/software) using statistical machine learning and deep learning using clinical data and/or long reads produced by 3rd generation sequencing technology such as PacBio, Moleculo, Oxford Nanopore, etc. This includes de novo genome assembly, single cell, cancer data analysis, time series data analysis and population structure to analyze big data, infer critical factors, predict the future and discover biological importance. -
Jin Billy Li
Associate Professor of Genetics
Current Research and Scholarly Interests The Li Lab is primarily interested in RNA editing mediated by ADAR enzymes. We co-discovered that the major function of RNA editing is to label endogenous dsRNAs as "self" to avoid being recognized as "non-self" by MDA5, a host innate immune dsRNA sensor, leading us to pursue therapeutic applications in cancer, autoimmune diseases, and viral infection. The other major direction of the lab is to develop technologies to harness endogenous ADAR enzymes for site-specific transcriptome engineering.
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Wen-yang Lin
Postdoctoral Research Fellow, Genetics
Current Research and Scholarly Interests The broad goal of my research interest is to identify intrinsic and extrinsic mediators of tumor growth and plasticity. My past research experiences will synergize with the expertise of Dr. Monte Winslow?s laboratory to allow the discovery of novel mechanisms of cancer progression. The integration of our molecular measurements with multiple types of ?omics? data will ultimately improve the diagnostic precision medicine.
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Joseph (Joe) Lipsick
Professor of Pathology, of Genetics and, by courtesy, of Biology
Current Research and Scholarly Interests Function and evolution of the Myb oncogene family; function and evolution of E2F transcriptional regulators and RB tumor suppressors; epigenetic regulation of chromatin and chromosomes; cancer genetics.
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Margaret Mahoney
Professional-NX, Genetics
Current Role at Stanford Faculty Affairs Admin. Dept. of Genetics
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Stephen B. Montgomery
Associate Professor of Pathology, and of Genetics
Current Research and Scholarly Interests We focus on understanding the effects of genome variation on cellular phenotypes and cellular modeling of disease through genomic approaches such as next generation RNA sequencing in combination with developing and utilizing state-of-the-art bioinformatics and statistical genetics approaches. See our website at http://montgomerylab.stanford.edu/
