School of Medicine
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Associate Professor of Psychiatry and Behavioral Sciences (General Psychiatry and Psychology-Adult)) at the Stanford University Medical Center
Current Research and Scholarly Interests Primary research interests include the nature and treatment of eating disorders
(particularly bulimia nervosa and binge eating disorder), the development and treatment of obesity, and the development and treatment of problematic eating patterns in patients following bariatric surgery.
Professor of Pediatrics (Hematology/Oncology) and of Genetics
Current Research and Scholarly Interests We investigate the mechanisms by which normal cells become tumor cells, and we combine genetics, genomics, and proteomics approaches to investigate the differences between the proliferative response in response to injury and the hyperproliferative phenotype of cancer cells and to identify novel therapeutic targets in cancer cells.
Assistant Professor (Research) of Psychiatry and Behavioral Sciences (Interdisciplinary Brain Science Research)
Current Research and Scholarly Interests The overarching goal of my research is to develop reliable computational methods that will allow for characterizing and modeling temporal dynamics of brain activity, without averaging data in either space or time. I firmly believe that the spatiotemporal richness in brain activity might hold the key to finding the person- and disorder-centric biomarkers. I am currently developing methods to model the temporal dynamics of brain activity in individuals with fragile X syndrome and healthy controls.
Kathleen M. Sakamoto
Shelagh Galligan Professor in the School of Medicine
Current Research and Scholarly Interests My research focuses on the molecular pathways that regulate normal and aberrant blood cell development, including acute leukemia and bone marrow failure syndromes. We are also studying novel drugs for treatment of cancer.
Associate Professor of Pediatrics (General Pediatrics) at the Lucile Salter Packard Children's Hospital and, by courtesy, of Health Research and Policy (Epidemiology)
Current Research and Scholarly Interests I conduct interdisciplinary research to understand child and parent health literacy as potentially modifiable determinants of child health disparities. I am principal investigator on an multi-site, randomized controlled trial to assess the efficacy of a low-literacy, early-childhood intervention designed to prevent obesity in the first two years of life. The aim of my current scholarship is to apply the health-literacy model to attenuate disparities for children with chronic illness.
Meera N. Sankar
Clinical Associate Professor, Pediatrics - Neonatal and Developmental Medicine
Current Research and Scholarly Interests My recent clinical research project involved being a recipient of UCSF sub-award grant for a Multicenter clinical research study-PDA Tolerate Trial- ( PDA: TO LEave it alone or Respond And Treat Early - Trial)Trial of Early Treatment of the patent ductus arteriosus versus Conservative Treatment.
Peter Luke Santa Maria
Assistant Professor of Otolaryngology-HNS (Otology and Neurotology) at the Stanford University Medical Center
Current Research and Scholarly Interests Tympanic membrane regeneration - novel treatment for healing chronic tympanic membrane perforations. Currently partnering with Astellas pharmaceuticals for a clinical trial.
Novel treatments for biofilms in chronic suppurative otitis media using a unique rodent model created in our lab.
Novel treatments for wound healing in intra oral wounds with potential applications to prevent post tonsillectomy wound healing.
Medical device for maintaining perioperative normothermia
Kavita Sarin, MD, PhD
Assistant Professor of Dermatology at the Stanford University Medical Center
Current Research and Scholarly Interests My research encompasses two main areas: 1) Using next-generation RNA, whole genome, and exome sequencing, we are investigating the genetic alterations involved in skin cancer progression, response to therapy, and other clinical outcomes and 2) We are developing and implementing genome-wide genetic risk prediction assessments for skin cancer into clinical use and studying the impact of this information on patient care.
Professor of Microbiology and Immunology
Current Research and Scholarly Interests Our laboratory studies virus-host interactions with an emphasis microRNA-mediated gene regulation and on translational control. The mechanism by which a liver-specific microRNA regulates hepatitis C virus genome replication is under intense scrutiny. In addition, the mechanism of internal ribosome entry in certain cellular and viral mRNAs and its biological role in growth and development is being investigated.
Assistant Professor of Pathology
Current Research and Scholarly Interests Our lab works at the interface of immunology, cancer biology, and genomics to study cellular and molecular mechanisms of the immune response to cancer. In particular, we are leveraging high-throughput genomic technologies to understand the dynamics of the tumor-specific T cell response to cancer antigens and immunotherapies (checkpoint blockade, CAR-T cells, and others). We are also interested in understanding the impact of immuno-editing on the heterogeneity and clonal evolution of cancer.
We previously developed genome sequencing technologies that enable epigenetic studies in primary human immune cells from patients: 1) 3D enhancer-promoter interaction profiling (Nat Genet, 2017), 2) paired epigenome and T cell receptor (TCR) profiling in single cells (Nat Med, 2018), 3) paired epigenome and CRISPR profiling in single cells (Cell, 2019), and high-throughput single-cell ATAC-seq in droplets (Nature Biotech, 2019). We used these tools to study fundamental principles of the T cell response to cancer immunotherapy (PD-1 blockade) directly in cancer patient samples (Nature Biotech, 2019; Nat Med, 2019).