School of Medicine
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Assistant Professor of Cardiothoracic Surgery at the Lucile Salter Packard Children's Hospital and at the Stanford University Medical Center
Current Research and Scholarly Interests Our lab aims to understand the biomechanics that govern a wide spectrum of congenital heart defects, and how those biomechanics change with contemporary operative repair strategies. We simulate operations virtually via CFD, and in ex vivo and in vivo animal models, and analyze how the changes we make alter fluid flow, pressure, and stresses throughout the system. We hope that these experiments can impact and optimize existing techniques that translate quickly to the operating room.
Professor of Pediatrics (Endocrinology) and, by courtesy, of Health Research and Policy (Epidemiology) at the Lucile Salter Packard Children's Hospital and at the Stanford University Medical Center
Bio Dr David M. Maahs is Professor of Pediatrics and Division Chief of Pediatric Endocrinology at Stanford University and the Lucile Packard Children?s Hospital. He earned his MD followed by Pediatric Residency at the University of New Mexico. After 3 years on New Mexico?s faculty, Dr. Maahs completed a Pediatric Endocrinology fellowship and a concurrent PhD in Epidemiology at the University of Colorado. He remained on Colorado?s faculty for 10 years, advancing to Professor of Pediatrics before moving to Stanford. Prior to his medical career, Dr. Maahs received a BA and MA in English from the University of Kansas and was inspired to pursue a medical career after serving in the Peace Corps with assignments in Tunisia and the Central African Republic.
Dr. Maahs? leadership experiences include being a past co-Chair (2013-16) for Protocols and Publications with the Type 1 Diabetes Exchange for which he continues as a Steering Committee member and Director of International Collaborations. This complements his role as Secretary-General for the International Society of Pediatric and Adolescent Diabetes (ISPAD, 2016-20) and Editor-in-Chief for the 2018 ISPAD Clinical Practice Consensus Guidelines. He currently serves on the Professional Practice Committee for the American Diabetes Association (ADA, 2016-18), which writes the annual ADA Standards of Care. Previously, he served on the ADA Scientific Sessions committee representing the Council on Youth. He has also served on national committees for the American Heart Association, the Pediatric Endocrine Society, and multiple journal editorial boards and review committees.
His scholarly interest is improving care and preventing complications in people with type 1 diabetes (T1D). Along with Dr Peter Chase, he is author of the 12th and 13th editions of Understanding Diabetes, or ?Pink Panther,? which are the most widely used educational books for children newly diagnosed with T1D, distributed internationally by the Juvenile Diabetes Research Fund (JDRF). More specifically, he has conducted epidemiologic studies that help generate hypotheses for clinical studies, including trials to develop artificial pancreas systems to improve glucose control, lower disease burden, and prevent diabetic complications. He is author or co-author of over 300 research publications. His multi-disciplinary research has been funded by the JDRF, the National Institutes of Diabetes and Digestive and Kidney Diseases (NIDDK), the Helmsley Charitable Trust, and the National Science Foundation (NSF).
Dr Maahs is Associate Director for the recently formed and NIDDK P30 funded Stanford University Diabetes Research Center (https://sdrc.stanford.edu). His collaborations extend to his role as Principal Investigator (PI) or steering committee member for NIH funded multi-center clinical trials including the FLEX, PERL, and ACTION studies as well as multiple Artificial Pancreas clinical trials. Education, mentorship, and training leadership includes being Program Director with Dr. Georgeanna Klingensmith on the Barbara Davis Center T32 and K12 training grants in Pediatric Endocrinology while at the University of Colorado. He is the PI on the Stanford NIH funded K12 "Training Research Leaders in Type 1 Diabetes.'
While in the Peace Corps, David met his wife, Christine Walravens, who is also a Pediatrician at Stanford. They enjoy outdoor activities and traveling with their children, Nicholas (22) and Natalia (16).
Ernest and Amelia Gallo Family Professor and Professor of Pediatrics and of Medicine
Current Research and Scholarly Interests Recent clinical studies, by us and others, have demonstrated that T cell based immunotherapy can eradicate cancers resistant to all other available therapies. Our program creates, develops and optimizes genetically engineered T cells to treat cancer. We link the bench with the bedside, developing novel therapies for early phase testing in clinical trials, while simultaneously conducting intensive studies on clinical samples obtained from patients treated on immunotherapy trials.
Professor (Research) of Microbiology and Immunology
Current Research and Scholarly Interests I'm interested in immune monitoring of T cell responses to chronic pathogens and cancer, and the correlation of T cell response signatures with disease protection.
Assistant Professor of Neurosurgery at the Stanford University Medical Center
Bio Dr. Mahaney is a Pediatric Neurosurgeon with clinical interest in Hydrocephalus, Craniovertebral Junction abnormalities, Spasticity, Spinal dysraphism and Myelomeningocele, Central Nervous System tumors, and Pediatric Epilepsy surgery. She completed residency training at the University of Iowa Hospitals and Clinics and subspecialty Pediatric Neurosurgery training at The Hospital for Sick Children in Toronto and the Barrow Neurologic Institute at Phoenix Children's Hospital. She is interested in advancing Neuro-endoscopic techniques in Pediatric Neurosurgical practice. Dr. Mahaney's research focuses on delineating the role of iron in the development of post-hemorrhagic hydrocephalus.
Ravindra Majeti MD, PhD
Professor of Medicine (Hematology)
Current Research and Scholarly Interests The Majeti lab focuses on the molecular/genomic characterization and therapeutic targeting of leukemia stem cells in human hematologic malignancies, particularly acute myeloid leukemia (AML). Our lab uses experimental hematology methods, stem cell assays, genome editing, and bioinformatics to define and investigate drivers of leukemia stem cell behavior. As part of these studies, we have led the development and application of robust xenotransplantation assays for human hematopoietic cells.
Senior Associate Dean, Faculty Development and Diversity, Professor of Pediatrics (Infectious Diseases) and of Health Research and Policy
Current Research and Scholarly Interests My research focuses on epidemiologic aspects of viral vaccines and perinatal HIV infection. This includes the molecular epidemiology of factors affecting the immunogenicity of oral polio vaccine (OPV) in developing areas of the world, and now the epidemiology of transmission and circulation of vaccine derived polioviruses in order to assist in global eradication of polio. I also work in development of methods to prevent breastfeeding transmission of HIV in Africa.
Associate Professor (Research), Radiation Oncology - Radiation and Cancer Biology
Current Research and Scholarly Interests My research interests focus on the design and discovery of synthetic, and natural product inspired small molecules which can be used as probes for developing understanding of biological phenomena, including protein-protein interactions and modulation of signal transduction pathways. My laboratory employs the tools of synthetic medicinal chemistry, molecular modeling and chemical biology for translational research in drug discovery, development, imaging and radiation.