School of Medicine
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Robert Kazimierz Lesniak
Bio Robert K. Le?niak joined the Medicinal Chemistry Knowledge Center at Stanford ChEM-H in 2018 as a postdoctoral fellow. Prior to coming to Stanford, he worked with Professor Chris Schofield at the University of Oxford, as a postdoctoral research associate, designing novel antibiotics for the European gram-negative antibacterial engine (ENABLE) and UK Medical Research Council (MRC). Dr Le?niak also completed his DPhil under the guidance of Professor Schofield as a BHF-CRE studentship recipient, which involved the design and implementation of small molecules targeting Fe(II), 2-oxoglutarate dependent oxygenase enzymes involved in carnitine biosynthesis and hypoxic response as a means to treat cardiovascular disease. In addition, work on small-molecule modulation of bacterial metallo-beta-lactamases to combat antibiotic resistance was also carried out. Dr Le?niak completed his undergraduate at the University of Bristol, and worked at GlaxoSmithKline, North Carolina, developing inhibitors of bromodomains and histone acetyl-transferases. He is currently working with Professor Thomas Montine at the Stanford School of Medicine on the design of neurotransmitter prodrugs.
Joseph (Joe) Lipsick
Professor of Pathology, of Genetics and, by courtesy, of Biology
Current Research and Scholarly Interests Function and evolution of the Myb oncogene family; function and evolution of E2F transcriptional regulators and RB tumor suppressors; epigenetic regulation of chromatin and chromosomes; cancer genetics.
Alarice Cheng-Yi Lowe
Associate Professor of Pathology at the Stanford University Medical Center
Bio Dr. Lowe joined the School of Medicine faculty in 2019. She received her undergraduate degree in Biology from MIT and her medical degree at UCSD, prior to residency and cytology fellowship at UCLA. In 2011, she joined the faculty at Brigham and Women's Hospital where she developed a research focus on Circulating Tumor Cells (CTCs) and the application of CTC technology to improve clinical diagnostics. Clinically, her interests focus on Cytopathology and Genitourinary Pathology.
Professor of Pathology
Current Research and Scholarly Interests We are interested in understanding how neural stem cells balance their self-renewal and differentiation and how deregulation of this process can result in brain tumor. We are also interested in mechanisms of neurodegeneration in Alzheimer’s and Parkinson’s diseases. We are using both Drosophila and mammalian models to address these fundamental questions.