School of Medicine
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Aida Habtezion MD MSc.
Associate Professor of Medicine (Gastroenterology and Hepatology)
Current Research and Scholarly Interests Leukocyte recruitment & immune responses in diseases affecting digestive organs
Professor of Political Science and, by courtesy, of Political Economics at the Graduate School of Business
Bio Jens Hainmueller is a Professor in the Department of Political Science at Stanford University and holds a courtesy appointment in the Stanford Graduate School of Business. He is also the Faculty Co-Director of the Stanford Immigration Policy Lab that is focused on the design and evaluation of immigration and integration policies and programs.
His research interests include immigration, statistical methods, political economy, and political behavior. He has published over 40 articles, many of them in top general science journals and top field journals in political science, statistics, economics, and business. He has also published three open source software packages and his research has received awards and funding from the Carnegie Corporation, the Russell Sage Foundation, the Robin Hood Foundation, the National Science Foundation, the Swiss SNF, the American Political Science Association, Schmidt Futures, the Society of Political Methodology, the National Bureau of Economic Research, and the Midwest Political Science Association.
Hainmueller received his PhD from Harvard University and also studied at the London School of Economics, Brown University, and the University of Tübingen. Before joining Stanford, he served on the faculty of the Massachusetts Institute of Technology.
Professor of Pediatrics (Neonatology) at the Lucile Packard Children's Hospital and, by courtesy, of Obstetrics and Gynecology at the Stanford University Medical Center
Current Research and Scholarly Interests 1. development of hospital operations centers coupled with sophisticated simulation capabilities
2. re-creation of near misses and adverse events
3. optimizing human and system performance during resuscitation
4. optimizing pattern recognition and situational awareness at the bedside
5. evaluation and optimization of debriefing
6. patient simulator design
Scott S. Hall, Ph.D
Professor of Psychiatry and Behavioral Sciences (Interdisciplinary Brain Sciences) at the Stanford University Medical Center
Current Research and Scholarly Interests My primary area of scholarly and clinical interest is the pathogenesis of problem behaviors shown by individuals diagnosed with intellectual and developmental disabilities (IDD), particularly those with neurogenetic forms of IDD, such as fragile X syndrome, Cornelia de Lange syndrome and Prader-Willi syndrome. My work aims to both advance understanding of these disorders and to identify effective new treatment approaches for pediatric and adult patient populations by state-of-the-art methodologies, such as brain imaging, eye tracking and functional analysis to determine how environmental and biological factors affect the development of aberrant behaviors in these syndromes. The end goal of my research is to create patient-specific methods for treating the symptoms of these disorders.
Research Scholar, School of Medicine - Biomedical Ethics
Bio Meghan Halley, PhD, MPH, is a Research Scholar in the Center for Biomedical Ethics (SCBE) at Stanford University. She completed her doctorate in medical anthropology from Case Western Reserve University in 2012, and additional training in health services research at the Palo Alto Medical Foundation Research Institute from 2012 through 2016. After a hiatus from research to care for her second child, who was born with a rare genetic condition that remains undiagnosed, Dr. Halley joined SCBE in 2020. Her current research focuses at the intersection of the ethics and economics of new genomic technologies. Her current projects include: 1) examining ethical issues related to sustainability and governance of patient data and relationships when large clinical genomic studies transition to new models of funding; 2) exploring how diverse stakeholders perceive value in the use of genome sequencing for diagnosis of rare diseases; and 3) developing new measures for assessing patient-centered outcomes in pediatric rare diseases. She is also a member of the patient and family advisory group of the Undiagnosed Diseases Network, where her son is a current participant.
Professor of Psychiatry and Behavioral Sciences
Current Research and Scholarly Interests Principal Investigator
Infrastructure to facilitate discovery of autism genes
The purpose of this project is to facilitate the discovery of the genes that contribute autism by maintaining an infrastructure which research groups studying the genetics of autism can work collaboratively. This will be
accomplished through workshops, a Virtual Private Network, and access to a database that includes phenotype and genotype data from all participating groups.
A California Population-Based Twin Study of Autism
This will address several fundamental questions: (1) What is the heritability of autism (2) What is the contribution of genetic factors to variation in symptom dimensions? (3) Is there a continuum between the quantitative neurocognitive traits and clinical disorder? (4) What proportion of the variance in the neurocognitive traits is accounted for by genetic and non-genetic factors?
Center for Integrating Ethics in Genetics Research(Cho)
The goal of this project is to serve as a center of excellence in neurogenetics research, to develop a national model for bench, to bedside research ethics consultation, and to provide training opportunity in biomedical ethics.
Gene, Brain and Behavior in Turner Syndrome(Reiss)
The primary objective of this project is to use advanced, multi-modal magnetic resonance imaging (MRI) techniques, analyses of X chromosome parent-of-origin and cognitive-behavioral assessment to elucidate the effects of monosomy and X-linked imprinting on neurodevelopment and neural function in a large cohort of young girls with Turner syndrome, pre-estrogen replacement.
Project F: Genomic Analysis in narcolepsy cataplexy
The goal of the project is to locate genes outside the HLA region that influence susceptibility to narcolepsy. In order to localize these genes we will carry out a linkage and association study in the most extensive world-wide collection of DNAs from well-characterized patients with narcolepsy and their families.
Professor of Pediatrics (Adolescent Medicine) and, by courtesy, of Epidemiology and Population Health and of Psychiatry and Behavioral Sciences
Current Research and Scholarly Interests Research focuses on developmental, cognitive and psychosocial factors involved in adolescents? and young adults? health-related decision-making, perceptions of risk and vulnerability, health communication and risk behavior. My research has focused on understanding and reducing health risk behaviors such as tobacco use, alcohol and marijuana use, risky driving, and risky sexual behavior.
Professor of Anesthesiology, Perioperative and Pain Medicine (Pediatric) and of Pediatrics (Critical Care) at the Stanford University Medical Center
Current Research and Scholarly Interests Dr. Hammer's primary research interests are pediatric pharmacology and perioperative care of children undergoing cardiac surgery. He has numerous funded research projects in these areas, including an NIH grant for $4.3 million to study the pharmacology of sodium nitroprusside, a drug commonly used for blood pressure control in the operating room and ICU. Dr. Hammer has two other NIH grants and other ongoing research projects in the area of pediatric pharmacology.
Lawrence Crowley, M.D., Endowed Professor in Child Health
Current Research and Scholarly Interests His research and clinical work focuses on the development of interventional techniques for fetal and neonatal treatment of congenital heart disease, pulmonary, vascular physiology, and the neurologic impact of open-heart surgery. He developed and pioneered the unifocalization procedure, in which a single procedure is used to repair a complex and life-threatening congenital heart defect rather than several staged open-heart surgeries as performed by other surgeons.
Clinical Assistant Professor, Pediatrics
Current Research and Scholarly Interests A bad latch means maternal excruciating pain, ineffective milk transfer with subsequent weight loss, hypoglycemia, higher risk of hyperbilirubinemia and dehydration fever.All of the above led to early cessation of breastfeeding; 46% of mothers who initiate exclusive breastfeeding stop within the first 12 weeks because of difficult latch. I developed a latch tutorial focusing on step-by step-in striations for achieving an effective, non-painful latch.
Antonio Hardan, M.D.
Professor of Psychiatry and Behavioral Sciences at the Stanford University Medical Center
Current Research and Scholarly Interests The neurobiology of autism
Neuroimaging in individuals with autism
Psychopharmacological treatment of children and adults with autism and/or developmental disorders
The neurobiology and innovative interventions of several neurogenic disorders including DiGeorge Syndrome (Velocardiofacial syndrome; 22q11.2 mutations), PTEN mutations, and Phelan McDermid Syndrome (22q13 mutations).
Assistant Professor of Neurobiology
Current Research and Scholarly Interests Our laboratory studies the mechanisms by which highly complex behaviors are mediated at the neuronal level, mainly focusing on the example of dynamic social interactions and the neural circuits that drive them. From dyadic interactions to group dynamics and collective decision making, the lab seeks a mechanistic understanding for the fundamental building blocks of societies, such as cooperation, empathy, fairness and reciprocity.
John A. Overdeck Professor, Professor of Statistics and of Biomedical Data Sciences
Current Research and Scholarly Interests Flexible statistical modeling for prediction and representation of data arising in biology, medicine, science or industry. Statistical and machine learning tools have gained importance over the years. Part of Hastie's work has been to bridge the gap between traditional statistical methodology and the achievements made in machine learning.
Melanie Hayden Gephart
Associate Professor of Neurosurgery and, by courtesy, of Neurology at the Stanford University Medical Center
Bio I am a brain tumor neurosurgeon, treating patients with malignant and benign tumors, including glioma, brain metastases, meningioma, vestibular schwannoma, and pituitary adenomas. Our lab seeks greater understanding of the genetic and epigenetic mechanisms driving tumorigenesis and disease progression in malignant brain tumors. We currently study the capacity of cellular and cell-free nucleic acids to inform cancer biology and response to therapy. We also use single cell and cell subtype-specific transcriptomics to identify and target infiltrating glioblastoma. We use these techniques to identify mechanisms of tumor migration, and to stop tumor growth. Our laboratory is a unique and collaborative working environment, engaged in a dynamic research environment at Stanford. Our laboratory space lies at the heart of the Stanford campus between the core campus and the medical facilities, emblematic of the translational aspects of our work.
Florette K. Gray Hazard
Associate Professor of Pathology and of Pediatrics at the Stanford University Medical Center
Current Research and Scholarly Interests My scholarly pursuits are primarily focused on the study of death and disease in the pediatric population. It is through this work that I am able to explore fundamental concepts of neoplasia, such as histogenesis and mutagenesis, while utilizing a variety of investigational techniques.
John P. Hegarty II
Instructor, Psychiatry and Behavioral Sciences - Child and Adolescent Psychiatry
Bio The overarching goal of my research is to identify neurobiological subgroups and develop objective biomarkers for individuals with psychiatric and neurological disorders in order to improve biologically-based diagnosis and advance the development of precision medicine for mental health. Biologically-based diagnosis and treatment are extremely limited for some psychiatric conditions, especially neurodevelopmental disorders such as autism spectrum disorder (ASD), but also critically-needed to increase early identification and improve treatment outcomes. My early career training has focused on developing expertise in non-invasive neuroimaging approaches for examining participants ranging from young children to adults and my research has focused on identifying the neurobiology underlying typical and atypical neurodevelopment.
Thus far in my early research career, my primary contributions to science fall within four major categories:
1) identifying the neural correlates of different cognitive and behavioral deficits, 2) investigating the neurobiological substrates of treatment response, 3) examining the etiological factors that contribute to atypical brain development in children with autism, and 4) summarizing and increasing accessibility to autism-related research. My earliest research investigated the neurobiology associated with the cognitive deficits of alexithymia, dyslexia, and stress to further develop theories of the underlying mechanisms that contribute to differences in cognitive and behavioral processing. My subsequent dissertation research, in which I began to focus on neurodevelopmental disorders, examined the neural correlates of treatment response to beta-blockers in adults with ASD and also assessed the contribution of cerebellar circuits to autism-related symptoms, which is well-supported from postmortem studies but understudied in clinical populations. During my postdoctoral training, I have been further developing skills for working with young children with and without neurodevelopmental disorders as well as utilizing advanced neuroimaging and neurophysiological approaches to examine the biological mechanisms underlying different types of cognitive and behavioral symptoms. My most recent research has focused on examining the neural correlates of response to behavioral interventions as well as examining the etiological factors that contribute to atypical brain development in twins with autism. The independent line of research that I will continue to develop in my research lab will aim to improve our understanding of typical and atypical brain development and identify objective biomarkers for advancing precision medicine.
Professor of Materials Science and Engineering and, by courtesy, of Bioengineering and of Chemical Engineering
Current Research and Scholarly Interests Protein engineering
Wm. LeRoy Heinrichs
Professor of Obstetrics and Gynecology, Emeritus
Current Research and Scholarly Interests Surgical simulation; team-training in virtual environments; online training of healthcare providers in virtual environments; tele-medicine for acute & chronic disease management in virtual environments
Edward C. and Amy H. Sewall Professor in the School of Medicine
Current Research and Scholarly Interests Our research focuses on the inner ear, from its earliest manifestation as one of the cranial placodes until it has developed into a mature and functioning organ. We are interested how the sensory epithelia of the inner ear that harbor the sensory hair cells develop, how the cells mature, and how these epithelia respond to toxic insults. The overarching goal of this research is to find was to regenerate lost sensory hair cells in mammals.
Associate Professor of Medicine (Biomedical Informatics), of Biomedical Data Science, of Surgery and, by courtesy, of Epidemiology and Population Health
Current Research and Scholarly Interests My background and expertise is in the field of computational biology, with concentration in health services research. A key focus of my research is to apply novel methods and tools to large clinical datasets for hypothesis generation, comparative effectiveness research, and the evaluation of quality healthcare delivery. My research involves managing and manipulating big data, which range from administrative claims data to electronic health records, and applying novel biostatistical techniques to innovatively assess clinical and policy related research questions at the population level. This research enables us to create formal, statistically rigid, evaluations of healthcare data using unique combinations of large datasets.
Professor of Civil and Environmental Engineering
Bio Lynn Hildemann's current research areas include the sources and dispersion of indoor aerosols, the physicochemical properties of organic aerosols, and assessment of human exposure to PM.
Prof. Hildemann received BS, MS, and PhD degrees in environmental engineering science from the California Institute of Technology. She is an author on >90 peer-reviewed publications, including two with over 1000 citations each, and another 6 with over 500 citations each. She has been honored with Young Investigator Awards from NSF and ONR, the Kenneth T. Whitby Award from the AAAR (1998), and Stanford's Gores Award for Teaching Excellence (2013); she also was a co-recipient of Atmospheric Environment?s Haagen-Smit Outstanding Paper Award (2001).
She has served on advisory committees for the Bay Area Air Quality Management District and for the California Air Resources Board. She has been an Associate Editor for Environmental Science & Technology, and Aerosol Science and Technology, and has served on the advisory board for the journal Environmental Science & Technology.
At Stanford, Prof. Hildemann is currently chair of the Department of Civil & Environmental Engineering. She has served as an elected member of the Faculty Senate, and chaired the School of Engineering Library Committee, the University Committee on Judicial Affairs, and the University Breadth Governance Board..
Susan R. Hintz, M.D., M.S. Epi.
Robert L. Hess Family Professor and Professor, by courtesy, of Obstetrics and Gynecology at the Lucile Salter Packard Children's Hospital
Current Research and Scholarly Interests 1) Early childhood neurodevelopmental outcomes, mortality and morbidities of ELBW, extremely premature, and high-risk infants; predictive clinical factors, evidence-based interventions
2) Use of advanced neuroimaging techniques in the premature and term infant; diagnostic findings, and predictors of neurodevelopmental outcomes
3) Advanced therapeutic modalities: HFOV, iNO, ECMO - implementation, indications, outcomes
4) Natural history and outcomes of complex fetal anomalies
Andrew R. Hoffman
Professor of Medicine (Endocrinology)
Current Research and Scholarly Interests Mechanism of genomic imprinting of insulin like growth factor-2 and other genes.Long range chromatin interactions Role of histone modifications and DNA methylation in gene expression.
Marie Hollenhorst, MD, PhD
Clinical Instructor, Pathology
Bio Dr. Hollenhorst is a physician and scientist with expertise in non-malignant hematology, transfusion medicine, and chemical biology. Dr. Hollenhorst values the one-on-one relationships that she forms with her patients, and strives to deliver the highest quality of care for individuals with blood diseases. Her experience caring for patients drives her to ask scientific questions in the laboratory, where she aims to bring a chemical approach to the study of non-malignant blood disease.
Dr. Hollenhorst pursued combined MD and PhD training at Harvard University, where she received a PhD in Chemical Biology under the mentorship of Professor Christopher T Walsh. She subsequently completed a residency in Internal Medicine at Brigham and Women's Hospital, a fellowship in Transfusion Medicine at Harvard Medical School, and a fellowship in Hematology at Stanford.
Dr. Hollenhorst has a particular interest in the biology of platelets, which are cellular fragments that help the blood to maintain a healthy balance between excessive bleeding and excessive clotting. Working in the laboratory of Professor Carolyn Bertozzi of Stanford Chemistry, Dr. Hollenhorst is studying sugar-containing molecules that are found within platelets and are important in controlling their function and lifespan.
Dr. Hollenhorst's research is supported by a Stanford Chemistry, Engineering & Medicine for Human Health Physician-Scientist Fellowship, a National Institutes of Health Individual Postdoctoral Fellowship, and a National Blood Foundation Early-Career Scientific Research Grant.
Professor of Statistics
Current Research and Scholarly Interests Our lab has been developing tools for the analyses of complex data structures, extending work on multivariate data to structured multitable table that include graphs, networks and trees as well as categorical and continuous measurements.
We created and support the Bioconductor package phyloseq for the analyses of microbial ecology data from the microbiome. We have specialized in developing interactive graphical visualization tools for doing reproducible research in biology.
Clinical Assistant Professor, Neurosurgery
Bio Dr. Hong specializes in the treatment of pediatric patients with neurosurgical conditions, with additional specialty training in the treatment of pediatric spinal disorders, including scoliosis. He completed his residency in his home state of Michigan at the Detroit Medical Center, and completed fellowship training at Rady Children's Hospital in San Diego, before becoming a part of Stanford Children's Health.
His clinical interests include brain tumors, epilepsy surgery, idiopathic scoliosis, Chiari malformation, vascular conditions, concussion, and will treat all other conditions within the specialty.
Clinical Professor, Anesthesiology, Perioperative and Pain Medicine
Current Research and Scholarly Interests Patient Safety and Simulation
Effective Use of Health Care Resources
Professor of Pediatrics (Endocrinology) and of Psychiatry and Behavioral Sciences at the Lucile Salter Packard Children's Hospital
Bio Dr. Hood directs NIH- and foundation-funded clinical research aimed at promoting health and quality of life outcomes for people with diabetes. He has expertise and experience with diabetes epidemiology and interventions, study design, methodology, data management, and advanced statistical methods. There are two content threads to his work: 1) construct prevention and treatment programs to address modifiable psychological and family factors that create barriers to optimal diabetes management, and 2) optimize the use of devices and technologies to improve health outcomes. With regard to the first thread, Dr. Hood has successfully implemented depression screening programs in tertiary diabetes and GI clinics within a Quality Improvement framework, and recently completed a large scale clinical trial on a distress prevention program for teens with type 1 diabetes. Dr. Hood manages and analyzes all the data from these studies. From a device and technology standpoint, Dr. Hood coordinates the Human Factors assessments in Drs. Maahs? and Buckingham?s closed loop studies and is recognized as one of the experts in this area nationally and internationally. In addition, he has implemented Human Factors assessments in national (e.g., T1D Exchange) studies and registries and is the lead psychologist on 2 of the 4 UC4 grants from NIDDK (Hovorka, PI; Bergenstal, PI). These assessments focus on uptake of devices and technologies, and determining strategies to promote uptake and optimize their use. Dr. Hood and his research team have published over 100 scientific articles on these topics and are active presenters at diabetes, behavioral medicine, and advocacy conferences.
Dr. Hood also works in clinical and service settings. Dr. Hood is a licensed clinical psychologist and is part of the diabetes care team at Stanford. He is the past chair of the American Diabetes Association?s Behavioral Medicine and Psychology Interest Group and is currently a member of the Research Policy Committee. He was also a member of the ADA?s Call to Congress in March 2017. Dr. Hood is an Associate Editor for both Diabetes Care and Pediatric Diabetes.
Rachel Knight Hopper
Clinical Associate Professor, Pediatrics - Cardiology
Current Research and Scholarly Interests Current research interests include:
PH related to prematurity and bronchopulmonary dysplasia
Right heart failure in children with pulmonary hypertension, imaging and biomarkers
Pulmonary hypertension related to congenital diaphragmatic hernia
Pulmonary vein stenosis in infants and children
Pulmonary hypertension in children with congenital heart disease
Clinical trials in children with PH
SM Hadi Hosseini
Assistant Professor (Research) of Psychiatry and Behavioral Sciences (Interdisciplinary Brain Science Research)
Current Research and Scholarly Interests Our lab?s research portfolio crosses multiple disciplines including computational neuropsychiatry, cognitive neuroscience, multimodal neuroimaging and neurocognitive rehabilitation. Our computational neuropsychiatry research mainly involves investigating alterations in the organization of connectome in various neurodevelopmental and neurocognitive disorders using state of the art neuroimaging techniques (fMRI, sMRI, DWI, functional NIRS) combined with novel computational methods (graph theoretical and multivariate pattern analyses).
The ultimate goal of our research is to translate the findings from computational neuropsychiatry research toward developing personalized interventions. We have been developing personalized interventions that integrate computerized cognitive rehabilitation, real-time functional brain imaging and neurofeedback, as well as virtual reality (VR) tailored toward targeted rehabilitation of the affected brain networks in patients with neurocognitive disorders.
Michael R. Howitt
Assistant Professor of Pathology and of Microbiology and Immunology
Current Research and Scholarly Interests Our lab is broadly interested in how intestinal microbes shape our immune system to promote both health and disease. Recently we discovered that a type of intestinal epithelial cell, called tuft cells, act as sentinels stationed along the lining of the gut. Tuft cells respond to microbes, including parasites, to initiate type 2 immunity, remodel the epithelium, and alter gut physiology. Surprisingly, these changes to the intestine rely on the same chemosensory pathway found in oral taste cells. Currently, we aim to 1) elucidate the role of specific tuft cell receptors in microbial detection. 2) To understand how protozoa and bacteria within the microbiota impact host immunity. 3) Discover how tuft cells modulate surrounding cells and tissue.
Joe Le Hsu
Assistant Professor of Medicine (Pulmonary and Critical Care) at the Stanford University Medical Center
Current Research and Scholarly Interests I am interested in understanding the host-pathogen interaction between Aspergillus fumigatus and the lung transplant recipient.
Clinical Associate Professor, Pediatrics - Rheumatology
Current Research and Scholarly Interests Pediatric Systemic Lupus Erythematosus;
Racial/Ethnic Differences in Pediatric Lupus Patients
Professor of Obstetrics and Gynecology (Reproductive and Stem Cell Biology), Emeritus
Current Research and Scholarly Interests Hormonal regulation of ovarian function; gonadotropin receptors and related genes, bioinformatic ananlyses of polypeptide hormones and receptors, follicle recruitment and GDF-9; analysis of oocyte and ovarian-expressed genes.
Ngan F. Huang
Assistant Professor of Cardiothoracic Surgery (Cardiothoracic Surgery Research)
Current Research and Scholarly Interests Dr. Huang's laboratory aims to understand the chemical and mechanical interactions between extracellular matrix (ECM) proteins and pluripotent stem cells that regulate vascular and myogenic differentiation. The fundamental insights of cell-matrix interactions are applied towards stem cell-based therapies with respect to improving cell survival and regenerative capacity, as well as engineered vascularized tissues for therapeutic transplantation.
Professor of Pediatrics (Genetics) at the Lucile Salter Packard Children's Hospital, Emerita
Current Research and Scholarly Interests I am interested in prenatal genetic screening and diagnosis.
Lynne C. Huffman
Associate Professor (Teaching) of Pediatrics (Developmental-Behavioral Pediatrics) and, by courtesy, of Psychiatry and Behavioral Sciences
Current Research and Scholarly Interests Research interests and activities include (1) shared decision-making in clinical care; (2) medical education research; (3) the early identification and treatment of behavioral problems, particularly in children with special health care needs; and (4) community-based mental health/educational program evaluation and outcomes measurement.
Professor of Neurology and, by courtesy, of Molecular and Cellular Physiology
Current Research and Scholarly Interests We are interested in the neuronal mechanisms that underlie synchronous oscillatory activity in the thalamus, cortex and the massively interconnected thalamocortical system. Such oscillations are related to cognitive processes, normal sleep activities and certain forms of epilepsy. Our approach is an analysis of the discrete components (cells, synapses, microcircuits) that make up thalamic and cortical circuits, and reconstitution of components into in silico computational networks.