School of Medicine

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  • Quanyi Zhao

    Quanyi Zhao

    Postdoctoral Research Fellow, Cardiovascular Medicine

    Bio Quanyi is a postdoctoral fellow in Cardiovascular Medicine. He studied cancer epigenomics at Wuhan University in China and received his PhD in biochemistry and molecular biology. He joined Quertermous lab after working in Dr. Kornberg's lab at UCSF as a postdoc in developmental biology. His current research focuses on how causal coronary artery disease (CAD) variations regulate transcription factors (TFs) binding and causal genes expression, and how the variations affect chromatin state, accessibility and chromosomal architecture in CAD associated loci.

  • Hong Zheng

    Hong Zheng

    Postdoctoral Research Fellow, Biomedical Informatics

    Bio I am currently a postdoctoral researcher working at Stanford University, Center for Biomedical Informatics Research, Gevaert Lab.

    I got my PhD from The University of Hong Kong, Department of Clinical Oncology, under the supervision of Prof. Maria Lung. I study bioinformatics and cancer genomics. My thesis title was Identification of Genetic Susceptibility Genes and Characterization of Somatic Mutations in Nasopharyngeal Carcinoma.

    My interests focus on big data in genomics and precision medicine. I work with multiple omics datasets, including whole-genome, whole-exome, transcriptome, methylome, etc. I am proficient in several programming languages (R, Python, Linux/Bash, and Perl), statistical analysis, and machine learning methods.

    My research has been focused on understanding the genetic and genomic basic of cancer by integrating and digging into the massive amount of sequencing datasets in cancer genomics.

    Know more about me at

  • Bo Zhou

    Bo Zhou

    Postdoctoral Research Fellow, Neurosciences

    Current Research and Scholarly Interests Genetic information encoded in our DNA sequence are inherited from our parents and determine our own unique appearance and predisposition to certain diseases. Recent scientific findings have revealed that patterns of molecular modification (methylation) on the Cs in our DNA sequence can also be inherited from our parents. These methylation patterns vary from individual to individual and regulate important biological processes inside the various cell types of our bodies. Although the mechanisms of how these methylation patterns regulate biological processes is very poorly understood, more and more cases have confirmed that diseases including many types of cancer may develop when erroneous DNA methylation occurs in an individual. Interestingly, in many instances, the DNA sequences inherited paternally and maternally are asymmetrically methylated, and this phenomenon, also known as imprinting, has been associated with the preferential silencing of either paternally or maternally inherited genes. Though this phenomenon is thought to occur throughout our DNA, due to mainly technological limitations, only a handful of such imprinted genes has been identified in humans, and as a result, very little is known about how the process of imprinting regulates our biology in healthy or diseased states including cancer, neurological disorders, and possibly psychiatric illnesses as well. I am interested in developing a method to not only capture the entire methylation pattern in one?s DNA but also place this this pattern in the context of paternal and maternal inheritance such that all the imprinted regions in one?s DNA can also be identified. Such a method will serve as an important stepping-stone in furthering our understanding of the rules and mechanisms that govern the biology of DNA methylation and how to leverage them in the treatment of human disease.

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