Orkan Ilbay

Postdoctoral Scholar, Pathology

Lab Affiliations

Andrew Fire, (2/3/2020)

All Publications

Publications (3)

All Publications (3)
Featured Publications (3)
Journal Articles (3)

Profiles With Related Publications

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Anne Brunet

Michele and Timothy Barakett Endowed Professor
Research Interests
Our lab studies the molecular basis of longevity. We are interested in the mechanism of action of known longevity genes, including FOXO and SIRT, in the mammalian nervous system. We are particularly interested in the role of these longevity genes in neural stem cells. We are also discovering novel genes and processes involved in aging using two short-lived model systems, the invertebrate C. elegans and an extremely short-lived vertebrate, the African killifish N. furzeri.

161 Total Publications
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Gerald Crabtree

David Korn, MD, Professor of Pathology and Professor of Developmental Biology
Research Interests
Chromatin regulation and its roles in human cancer and the development of the nervous system. Engineering new methods for studying and controlling chromatin and epigenetic regulation in living cells.

265 Total Publications
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Scott Dixon

Associate Professor of Biology
Research Interests
My lab is interested in the relationship between cell death and metabolism. Using techniques drawn from many disciplines my laboratory is investigating how perturbation of intracellular metabolic networks can result in novel forms of cell death, such as ferroptosis. We are interested in applying this knowledge to find new ways to treat diseases characterized by insufficient (e.g. cancer) or excessive (e.g. neurodegeneration) cell death.

98 Total Publications
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Amelia Farinas

Ph.D. Student in Neurosciences, admitted Autumn 2020

1 Total Publications
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Jessica Feldman

Associate Professor of Biology
Research Interests
Cell differentiation requires cells to polarize, translating developmental information into cell-type specific arrangements of intracellular structures. The major goal of the research in my laboratory is to understand how cells build these functional intracellular patterns during development, specifically focusing on the molecules and mechanisms that build microtubules at cell-type specific locations and the polarity cues that guide this patterning in epithelial cells.

40 Total Publications
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Andrew Fire

George D. Smith Professor of Molecular and Genetic Medicine and Professor of Pathology and of Genetics
Research Interests
While chromosomal inheritance provides cells with one means for keeping and transmitting genetic information, numerous other mechanisms have (and remain to be) discovered. We study novel cellular mechanisms that enforce genetic constancy and permit genetic change. Underlying our studies are questions of the diversity of inheritance mechanisms, how cells distinguish such mechanisms as "wanted" versus "unwanted", and of the consequences and applications of such mechanisms in health and disease.

191 Total Publications
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Miriam B. Goodman

Mrs. George A. Winzer Professor of Cell Biology
Research Interests
We study the molecular events that give rise to the sensation of touch and chemical stressors that compromise touch sensation in C. elegans. To do this, we use a combination of quantitative behavioral analysis, genetics, in vivo electrophysiology, and heterologous expression of ion channels. We collaborate with physicists and other physiologist to expand our experimental research.

112 Total Publications
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Hongfei Ji

Postdoctoral Scholar, Molecular and Cellular Physiology

14 Total Publications
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Stuart Kim

Professor of Developmental Biology, Emeritus
Research Interests
Mechanisms of Aging in C. elegans and humans.

57 Total Publications
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Xing Liang

Basic Life Res Scientist
Research Interests
Mechanism of MT polarity establishment during PVD neuron dendrite outgrowing in C. elegans.

8 Total Publications
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Daniel Matus

Postdoctoral Scholar, Molecular and Cellular Physiology

5 Total Publications
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Steven Lee Mcintire

Clinical Associate Professor, Neurology & Neurological Sciences
Clinical Focus
Neurology, Comprehensive/General Neurology

25 Total Publications