Clinical Focus

  • Cancer > Cutaneous (Dermatologic) Oncology
  • Dermatology
  • Mohs Surgery
  • Dermatological Surgery
  • Laser Surgery
  • Skin oncology in transplant patients
  • Melanoma and Skin Cancer

Academic Appointments

Honors & Awards

  • Distinguished Service Award, American College of Mohs Surgery (2013)
  • Connecticut Magazine Top Doctors, Connecticut Magazine (2011)
  • Connecticut Magazine Top Doctors, Connecticut Magazine (2010)
  • Connecticut Magazine Top Doctors, Connecticut Magazine (2009)
  • Connecticut Magazine Top Doctors, Connecticut Magazine (2008)
  • Connecticut Magazine Top Doctors, Connecticut Magazine (2007)
  • Connecticut Magazine Top Doctors, Connecticut Magazine (2006)
  • Cutting Edge Research Grant Award, American Society of Dermatologic Surgery` (2003)

Professional Education

  • Fellowship:Yale University (2002) CT
  • Board Certification: Dermatology, American Board of Dermatology (2001)
  • Residency:Northwestern Univ - McGaw Medical Center (2001) IL
  • Internship:University of Chicago Hospitals (1998) IL
  • Medical Education:Northwestern University Feinberg SOM (1997) IL

Research & Scholarship

Current Research and Scholarly Interests

High risk squamous cell carcinoma; frozen histopathology; reconstructive surgery.

Clinical Trials

  • Vismodegib in Treating Patients With Basal Cell Carcinoma Not Recruiting

    The purpose of this study is to learn about the effect of vismodegib on sporadic basal cell carcinoma (BCCs) prior to surgical removal.

    Stanford is currently not accepting patients for this trial. For more information, please contact Irene Bailey, 650-721-7149.

    View full details

  • A Study of Vismodegib With Surgery in Patients With Previously Untreated Basal Cell Carcinoma Not Recruiting

    This randomized, double-blind, placebo-controlled study will assess the efficacy and safety of vismodegib with surgery in patients with basal cell carcinoma. Patients will be randomized to receive oral daily doses of vismodegib 150 mg or matching placebo. The anticipated time on study drug treatment is 12 weeks.

    Stanford is currently not accepting patients for this trial. For more information, please contact Irene Bailey-Healy, 408-892-7261.

    View full details

  • Analysis of Cutaneous and Hematologic Disorders by High-Throughput Nucleic Acid Sequencing Recruiting

    The goal of this study is to identify genetic changes associated with the initiation, progression, and treatment response of response of cutaneous and hematologic disorders using recently developed high-throughput sequencing technologies. The improved understanding of the genetic changes associated with cutaneous and hematologic disorders may lead to improved diagnostic, prognostic and therapeutic options for these disorders.

    View full details


Journal Articles

  • An investigator-initiated open-label clinical trial of vismodegib as a neoadjuvant to surgery for high-risk basal cell carcinoma JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY Ally, M. S., Aasi, S., Wysong, A., Teng, C., Anderson, E., Bailey-Healy, I., Oro, A., Kim, J., Chang, A. L., Tang, J. Y. 2014; 71 (5): 904-U304
  • Recurrent point mutations in the kinetochore gene KNSTRN in cutaneous squamous cell carcinoma NATURE GENETICS Lee, C. S., Bhaduri, A., Mah, A., Johnson, W. L., Ungewickell, A., Aros, C. J., Nguyen, C. B., Rios, E. J., Siprashvili, Z., Straight, A., Kim, J., Aasi, S. Z., Khavari, P. A. 2014; 46 (10): 1060-1062

    View details for DOI 10.1038/ng.3091

    View details for Web of Science ID 000342554100007

  • Single-stage turn-over muscular hinge flap with Burow's full-thickness skin graft to repair oral commissure defect. Dermatologic surgery Wysong, A., Aasi, S. Z. 2013; 39 (10): 1530-1534

    View details for DOI 10.1111/dsu.12216

    View details for PubMedID 23590278

  • Comment on basal cell carcinoma rebound after cessation of vismodegib in an individual with basal cell nevus syndrome. Dermatologic surgery Ally, M. S., Wysong, A., Tang, J. Y., Aasi, S. 2013; 39 (9): 1413-1414

    View details for DOI 10.1111/dsu.12250

    View details for PubMedID 23682843

  • Update on metastatic basal cell carcinoma: a summary of published cases from 1981 through 2011. JAMA dermatology Wysong, A., Aasi, S. Z., Tang, J. Y. 2013; 149 (5): 615-616

    View details for DOI 10.1001/jamadermatol.2013.3064

    View details for PubMedID 23677097

  • New Onset of Keratoacanthomas After Vismodegib Treatment for Locally Advanced Basal Cell Carcinomas: A Report of 2 Cases JAMA DERMATOLOGY Aasi, S., Silkiss, R., Tang, J. Y., Wysong, A., Liu, A., Epstein, E., Oro, A. E., Chang, A. L. 2013; 149 (2): 242-243
  • Is Tanning Bed Exposure Associated With Aggressive Basal Cell Carcinoma? JOURNAL OF CLINICAL ONCOLOGY Gamba, C. A., Wysong, A., Million, L., Aasi, S., Kim, J., Tang, J. Y. 2012; 30 (32): E333-E336

    View details for DOI 10.1200/JCO.2012.42.1008

    View details for Web of Science ID 000310914800006

    View details for PubMedID 23008324

  • Hemorrhagic complications in dermatologic surgery DERMATOLOGIC THERAPY Bunick, C. G., Aasi, S. Z. 2011; 24 (6): 537-550


    The ability to recognize, manage, and, most importantly, prevent hemorrhagic complications is critical to performing dermatologic procedures that have safe and high quality outcomes. This article reviews the preoperative, intraoperative, and postoperative factors and patient dynamics that are central to preventing such an adverse outcome. Specifically, the role that anticoagulants and anti-platelet agents, hypertension, and other medical conditions play in the development of postoperative hemorrhage are discussed. In addition, this article provides practical guidelines on managing bleeding during and after surgery.

    View details for DOI 10.1111/j.1529-8019.2012.01454.x

    View details for Web of Science ID 000303004600004

    View details for PubMedID 22515669

  • Cosmetic concerns and management strategies to combat aging MATURITAS Robinson, D. M., Aasi, S. Z. 2011; 70 (3): 256-260


    Multiple modalities with varying degrees of complexity and risks exist in the treatment of the aging face. Paramount to all treatment paradigms is photoprotection to prevent further damage. Intervetions should be geared towards addressing the intrinsic and extrinsic signs of aging and can include topical retinoid therapy, superficial chemical and laser resurfacing, botulinum toxin and soft tissue fillers. The combination of these primary, secondary, and tertiary therapies will address the underlying pathophysiologic changes of the aging face and thus will provide the optimal aesthetic outcome.

    View details for DOI 10.1016/j.maturitas.2011.07.020

    View details for Web of Science ID 000296684900009

    View details for PubMedID 21873005

  • Cancer of the skin Cancer Principles and Practice of Oncology Reszko A, Aasi SZ, Wilson LD, Leffell DJ 2011; 9: 1610-1633
  • Melanoma and Non-melanoma Skin Cancer Dermatology A Pictorial Review Aasi SZ, Cox KM 2010; 2: 193-206
  • Commentary: Expanding the Donor Site Options for Full-Thickness Skin Grafts Dermatol Surg. Aasi SZ 2010; 36: 532-533
  • Z-plasty made simple. Dermatology research and practice Aasi, S. Z. 2010; 2010: 982623-?


    A Z-plasty is a critical and reliable technique that is useful for scar revisions and correction of free margin distortion. A Z-plasty can help lengthen a contracted scar, change the direction of a scar so that it is better aligned with the relaxed skin tension lines, or interrupt and break a scar for better camouflage. This article will review the technique of a basic Z-plasty as well as provide case examples of its use in free margin distortion and scar revision.

    View details for DOI 10.1155/2010/982623

    View details for PubMedID 21789038

  • Mohs micrographic surgery histopathology concordance JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY Mariwalla, K., Aasi, S. Z., Glusac, E. J., Leffell, D. J. 2009; 60 (1): 94-98


    The low recurrence rate and tissue-sparing benefit associated with Mohs micrographic surgery (MMS) requires accurate interpretation of frozen sections by the MMS surgeon.We sought to assess concordance between dermatopathologists and MMS surgeons when reporting cutaneous malignancy in the MMS setting.This study is a retrospective analysis of 1156 slides submitted during 10 years as part of a pre-existing randomized, blinded, quality assurance protocol. Slides were read by one of 5 dermatopathologists and represent cases from 3 MMS surgeons and 5 MMS fellows. Agreement or disagreement was recorded.Of the 1156 slides, 32 slides (2.8%) were disparate. Aside from differences regarding intraepidermal neoplasia, the concordance rate was 99.7%.This study represents data collected at a single institution in the United States alone.There was statistically significant concordance between MMS surgeons and dermatopathologists in frozen section interpretation in the MMS setting. Discordance was primarily related to the interpretation of in situ malignancy.

    View details for DOI 10.1016/j.jaad.2008.09.061

    View details for Web of Science ID 000262261700010

    View details for PubMedID 19103361

  • Skin cancer prevention and photo protection in organ transplant recipients Skin Diseases in Organ Transplantation Aasi SZ 2008: 295-301
  • Dermatologic surgery: introduction to anatomy and approach Fitzpatrick's Dermatology in General Medicine Aasi SZ, Pennington B 2008; 7: 2289-2301
  • Free margin distortion Complications in Cutaneous Surgery Aasi SZ 2008: 95-114
  • Cancer of the skin Cancer Principles and Practice of Oncology Thomas VD, Aasi SZ, Wilson LD, Leffel DJ 2008; 8: 863-1888
  • Dermatologic diseases and disorders Geriatrics Review Syllabus Aasi SZ 2006; 6: 309-319
  • Multiple facial angiofibromas: A cutaneous manifestation of Birt-Hogg-Dube syndrome JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY Schaffer, J. V., Gohara, M. A., McNiff, J. M., Aasi, S. Z., Dvoretzky, I. 2005; 53 (2): S108-S111


    Birt-Hogg-Dubé syndrome (BHDS) is an uncommon autosomal dominant genodermatosis characterized by a triad of skin tumors--fibrofolliculomas, trichodiscomas, and acrochordons--together with an increased risk of renal tumors and spontaneous pneumothoraces. This report describes multiple facial angiofibromas as the predominant initial manifestation of BHDS. The patient had a total of 41 facial papules removed via shave excision, initially for diagnostic and then for therapeutic purposes; histologic evaluation revealed diagnostic features of angiofibroma in 39 lesions and fibrofolliculoma in only 2. BHDS should be considered, along with tuberous sclerosis and multiple endocrine neoplasia type 1, in the differential diagnosis of multiple facial angiofibromas, particularly when onset is in adulthood.

    View details for DOI 10.1016/j.jaad.2004.11.021

    View details for Web of Science ID 000231081400003

    View details for PubMedID 16021156

  • Bilobed transposition flap DERMATOLOGIC CLINICS Aasi, S. Z., Leffell, D. J. 2005; 23 (1): 55-?


    This article reviews the indications and techniques for performing a bilobed flap for reconstruction of surgical wounds. Various examples of surgical defects where a bilobed flap can be used are shown. Possible complications and pitfalls are also reviewed.

    View details for DOI 10.1016/j.det.2004.08.004

    View details for Web of Science ID 000226324900006

    View details for PubMedID 15620619

  • Ellipse, ellipse variations and dog-ear repairs Surgery of the Skin Book SE, Aasi SZ, Leffell DJ 2005: 259-272
  • Cancer of the skin Cancer Principles and Practice of Oncology Aasi SZ, Leffell DJ 2005; 7: 1717-1744
  • Idiopathic eruptive macular pigmentation: A case of 21 years' duration JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY Mehta, S., Aasi, S., Cole, R., Chu, P., Weinberg, J. M. 2003; 49 (5): S280-S282


    Idiopathic eruptive macular pigmentation is a rare condition characterized by asymptomatic pigmented macules involving the neck, trunk, and proximal portions of the extremities. Age at onset usually varies from 1 to 20 years. The lesions usually appear abruptly and remit spontaneously over months to years. An unusual case of a 24-year-old woman with idiopathic eruptive macular pigmentation lasting 21 years was characterized by several periods of spontaneous resolution followed by recurrences.

    View details for DOI 10.1067/S0190-9622(03)00745-X

    View details for Web of Science ID 000186362900017

    View details for PubMedID 14576654

  • Complications in dermatologic surgery - How safe is safe? ARCHIVES OF DERMATOLOGY Aasi, S. Z., Leffell, D. J. 2003; 139 (2): 213-214

    View details for Web of Science ID 000180971400012

    View details for PubMedID 12588228

  • Dermatologic diseases and disorders Geriatrics Review Syllabus Aasi SZ, Cook B 2002; 5: 390-399
  • Aquagenic palmoplantar keratoderma J Am Acad Dermatol Yan AC, Aasi SZ, Alms DJ, Heymann WR, Paller AS, Honig PJ 2001: 696-699
  • Autoantibodies to type VII collagen have heterogeneous subclass and light chain compositions and their complement-activating capacities do not correlate with the inflammatory clinical phenotype. J Clinical Immunol. Gandhi K, Chen M, Aasi SZ, Lapiere JC, Woodley DT, Chan LS 2000; 20: 416-423
  • Successful correction of depressed scars of the forehead secondary to trauma and morpheme en coup de saber by autologous free dermal-fat graft. Dermatol Surg. Lapiere JC, Aasi SZ, Cook B, Montalvo A 2000: 793-796

Books and Book Chapters

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