School of Medicine
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Lisa Zaba, MD, PhD
Clinical Associate Professor, Dermatology
Bio Lisa Zaba M.D. Ph.D., is Clinical Associate Professor of Dermatology and Director of the South Bay Cutaneous Oncology Program. She has a special interest in managing skin complications in cancer patients while they receive treatment including skin rashes, graft versus host disease, and skin cancer. She also has a special interest in rheumatologic diseases and autoimmunity that can be caused by some forms of immune based chemotherapeutics. At the South Bay Cancer Center (CCSB) she leads the multi-disciplinary melanoma clinic. Dr. Zaba completed medical school at Cornell University, PhD in immunology at Rockefeller University, Residency and Post-Doc at Stanford University in 2013.
Clinical Associate Professor, Psychiatry and Behavioral Sciences - Child and Adolescent Psychiatry
Current Research and Scholarly Interests Dr. Zack is involved with ongoing research related to the treatment of adolescent and adult trauma (Trauma Focused Cognitive Behavioral Therapy - TF-CBT; Prolonged Exposure - PE), and the effective provision of Dialectical Behavior Therapy (DBT) to adolescent girls and women with disorder of emotion regulation. She additionally studies Acceptance and Commitment Therapy (ACT) for adolescent girls with anxiety. More broadly she is interested in the impact of Evidenced Based Treatments on improving quality of life, and helping individuals find the right match for clinical care. Research is conducted through the Early Life Stress and Pediatric Anxiety Disorders Program at Stanford Children's Hospital and the Stanford Dialectical Behavior Therapy Program.
Ken Zafren, MD FAAEM FACEP FAWM
Clinical Professor, Emergency Medicine
Current Research and Scholarly Interests High altitude medicine, AMS, HACE, HAPE, cold injuries, including hypothermia and frostbite, emergency medical services, wilderness medicine, mountain rescue, thrombosis, international medicine, travel medicine, emergency medicine, resuscitation
Professor of Radiology (Neuroimaging and Neurointervention)
Current Research and Scholarly Interests Improving medical image quality using deep learning artificial intelligence
Imaging of cerebral hemodynamics with MRI and CT
Noninvasive oxygenation measurement with MRI
Clinical imaging of cerebrovascular disease
Imaging of cervical artery dissection
MR/PET in Neuroradiology
Resting-state fMRI for perfusion imaging and stroke
Yulia Zak, MD
Clinical Assistant Professor, Surgery - General Surgery
Bio Dr. Yulia Zak earned her medical degree from SUNY Downstate Medical Center before completing general surgery residency at Stanford University and advanced minimally invasive gastrointestinal and bariatric fellowship training at the Massachusetts General Hospital. Dr. Zak is certified by the American Board of Surgery and American Society for Metabolic and Bariatric Surgery. She has also completed the Stanford Surgical Education and Simulation fellowship and was previously an Assistant Program Director for the general surgery residency program at Mount Sinai Beth Israel. Dr. Zak joined the faculty at Stanford in 2018 and is the current Fellowship Associate Program Director. Her current clinical practice is focused on bariatrics, foregut and abdominal wall procedures. Her academic interests include quality improvement, surgical education, and bariatric outcomes.
Clinical Assistant Professor, Radiation Oncology - Radiation Therapy
Bio Dr. Zaky is a board certified Radiation Oncologist. She received a Bachelor?s of Science in Biomedical/Electrical Engineering at Marquette University. She worked in research and development as an Engineer, and eventually received a Masters of Science in Immunology from Albany Medical College. Her research thesis focused on a novel therapy to treat hormone-receptor positive breast cancer. She continued to study breast cancer with her research during her Radiation Oncology residency; she integrated her research in the laboratory with her clinical research in triple-negative breast cancer. Since completing residency, she has worked as a general radiation oncologist, and her special interests include breast cancer, skin cancer, CNS tumors and stereotactic radiotherapy.
Associate Professor of Medicine (Pulmonary and Critical Care Medicine) at the Stanford University Medical Center
Current Research and Scholarly Interests 1. Development and evaluation of prognostic and diagnostic integral biomarkers in PAH.
2. Prevalence and Treatment of Insulin Resistance in PAH.
3. Role of inflammation and proteomic signature in PAH
4. Development of novel therapeutics (bench to bedside) including FK506 & Elastase Inhibition in PAH.
5. Assessment of Vasoreactivity (gain and loss) in pulmonary arterial hypertension
6. Assessment of microvascular function in PAH.
Marguerite Blake Wilbur Professor in Natural Science and Professor, by courtesy, of Physics
Current Research and Scholarly Interests My research group is exploring a variety of topics that range from the basic understanding of chemical reaction dynamics to the nature of the chemical contents of single cells.
Under thermal conditions nature seems to hide the details of how elementary reactions occur through a series of averages over reagent velocity, internal energy, impact parameter, and orientation. To discover the effects of these variables on reactivity, it is necessary to carry out studies of chemical reactions far from equilibrium in which the states of the reactants are more sharply restricted and can be varied in a controlled manner. My research group is attempting to meet this tough experimental challenge through a number of laser techniques that prepare reactants in specific quantum states and probe the quantum state distributions of the resulting products. It is our belief that such state-to-state information gives the deepest insight into the forces that operate in the breaking of old bonds and the making of new ones.
Space does not permit a full description of these projects, and I earnestly invite correspondence. The following examples are representative:
The simplest of all neutral bimolecular reactions is the exchange reaction H H2 -> H2 H. We are studying this system and various isotopic cousins using a tunable UV laser pulse to photodissociate HBr (DBr) and hence create fast H (D) atoms of known translational energy in the presence of H2 and/or D2 and using a laser multiphoton ionization time-of-flight mass spectrometer to detect the nascent molecular products in a quantum-state-specific manner by means of an imaging technique. It is expected that these product state distributions will provide a key test of the adequacy of various advanced theoretical schemes for modeling this reaction.
Analytical efforts involve the use of capillary zone electrophoresis, two-step laser desorption laser multiphoton ionization mass spectrometry, cavity ring-down spectroscopy, and Hadamard transform time-of-flight mass spectrometry. We believe these methods can revolutionize trace analysis, particularly of biomolecules in cells.
Christopher K. Zarins
Walter Clifford Chidester and Elsa Rooney Chidester Professor of Surgery, Emeritus
Current Research and Scholarly Interests Hemodynamic factors in atherosclerosis, pathogenesis of, aortic aneurysms, carotid plaque localization and complication, anastomotic intimal hyperplasia, vascular biology of artery wall, computational fluid dynamics as applied to blood flow and vascular disease.
James L. Zehnder, M.D.
Professor of Pathology (Research) and of Medicine (Hematology) at the Stanford University Medical Center
Current Research and Scholarly Interests Our laboratory focuses on translational research in 2 main areas - genomic approaches to diagnosis and minimal residual disease testing for patients with cancer, and molecular basis of disorders of thrombosis and hemostasis. My clinical focus is in molecular pathology, diagnosis and treatment of disorders of hemostasis and thrombosis and general hematology.
Clinical Assistant Professor, Psychiatry and Behavioral Sciences
Bio Dr. Zein received her dual bachelor?s degrees in Anthropology and Physiological Science at UCLA and worked initially as a healthcare consultant, developing programs that improve healthcare access for vulnerable populations. She returned to school to pursue a Masters in Public Health at Johns Hopkins University, where she further developed her interests in the intersection of medicine and broader social-cultural themes, particularly the impact on mental health. Her research foci were disaster response interventions for physical and mental health and the impact of the built environment on public health. During her masters, she worked with the International Rescue Committee in Baltimore to help address the acculturation and psychological stress the Baltimore refugee population faced in resettlement.
In 2010, Dr. Zein began her medical training at McGill University in Montreal, Canada. During medical school she continue to pursue interests in global and cultural health. She represented McGill nationally as the Global Health Advocate in the Canadian Federation of Medical Students, and focused on national and local clinical projects to support refugee and asylum seeker access to medical and mental health treatment. She was awarded the Mona Bronfman Sheckman Prize in Psychiatry for her work. During her psychiatry residency training at New York University (NYU), Dr. Zein continued pursuing her interest in global mental health, working as a group leader for refugees/asylum seekers in the Bellevue Survivors of Torture program, and the Association for Culture and Psychiatry. She also became interested in Integrated Behavioral Health, particularly the University of Washington's Ambulatory Integration of the Medical and Social (AIMs) model, or Collaborative Care Model. She founded the Integrated Behavioral Health resident working group and designed a two-year resident training program in the Collaborative Care Model as well as pioneered other electives in HIV psychiatry and psych-oncology. She completed training in the AIMs model and also was part of an intensive collaborative pilot with the AIMs center to a complete a quality-improvement (QI) project in the Bellevue Hospital primary care site. As part of the two-year resident training program she developed a Collaborative Care model in one of NYU Langone-Brooklyn's FQHC sites. In her last two years of residency she was an APA Leadership Fellow, and served on the APA Consult-Liaison Psychiatry Committee. She worked on a Decisional Capacity Guidelines paper with other committee members, and presented on Consult Liaison educational opportunities and Integrated Behavioral Health Models at the APA conference. She completed residency as a chief resident and won awards for Excellence in Resident Teaching as well as for humanism and clinical excellence in the Comprehensive Psychiatric Emergency Program
Dr. Zein completed her Consult Liaison Fellowship at Stanford and has remained as clinical faculty. She is currently serving as an attending psychiatrist on the General, Intensive Care, and ED-Psychiatry consult services as well as developing an Integrated Behavioral Health model for the Stanford Primary Care Clinic serving Cisco employees and their families.
Associate Professor of Radiology (Neuroimaging and Neurointervention) at the Stanford University Medical Center
Bio Dr. Michael Zeineh received a B.S. in Biology at Caltech in 1995 and obtained his M.D.-Ph.D. from UCLA in 2003. After internship also at UCLA, he went on to radiology residency and neuroradiology fellowship both at Stanford. He has been an assistant professor of radiology since 2010. Combining clinical acumen in neuroradiology with advanced MRI acquisition and image processing as well as histologic validation, Dr. Zeineh hopes to advance the care of patients with neurodegenerative disorders. In particular, he is interested in Alzheimer's disease, sports-related mild traumatic brain injury, and chronic fatigue syndrome. Additionally, he is specifically interested and has over 20 years of experience studying hippocampal anatomy and pathology.
Associate Professor (Research) of Psychiatry and Behavioral Sciences (Sleep Medicine)
Current Research and Scholarly Interests Dr. Zeitzer is a circadian physiologist specializing in the understanding of the impact of light on circadian rhythms and other aspects of non-image forming light perception.
He examines the manner in which humans respond to light and ways to manipulate this responsiveness, with direct application to jet lag, shift work, and altered sleep timing in teens. Dr. Zeitzer has also pioneered the use of actigraphy in the determination of epiphenomenal markers of psychiatric disorders.
Bing Melody Zhang
Clinical Assistant Professor, Pathology
Current Research and Scholarly Interests My main research interests lie in the following areas:
1) Using genetic/genomic approaches to study the genotype-phenotype correlation of inherited non-malignant hematologic disorders, especially platelet disorders.
2) Development and application of molecular assays for clinical testing to support hematopoietic stem cell transplantation and solid organ transplantation.
3) NGS-based TCR/Ig clonality/MRD diagnostic testing.
4) HLA-related disease association and pharmacogenetic testing.
Clinical Assistant Professor, Neurology & Neurological Sciences
Bio Dr. Niushen Zhang specializes in the treatment of headache and facial pain. Dr. Zhang has a special interest in complementary and alternative medicine for the treatment of headaches and facial pain. She is the Director of the Headache Fellowship Program at Stanford.
Professor (Research) of Neurosurgery
Current Research and Scholarly Interests My lab is focused on developing novel therapeutic methods against stroke using rodent models. We study protective effect of postconditioning, preconditioning and mild hypothermia. The rationale for studying three means of neuroprotection is that we may discover mechanisms that these treatments have in common. Conversely, if they have differing mechanisms, we will be able to offer more than one treatment for stroke and increase a patient’s chance for recovery.
Maisa Ziadni, PhD
Instructor, Anesthesiology, Perioperative and Pain Medicine
Current Research and Scholarly Interests Development and testing of novel interventions for chronic pain.
Understanding mechanisms of treatment among patients with chronic with pain.
Understanding predictors of opioid use among patients with chronic pain.
Clinical Assistant Professor, Medicine - Gastroenterology & Hepatology
Bio I am initially a Pittsburgh, PA native, but have been at Stanford University since 2012 for residency, fellowship, and now as faculty. It is exciting to be affiliated with one of the most dynamic and innovative medical institutions worldwide.
My clinical and research interests focus on functional, motility, and esophageal disorders of the gastrointestinal tract. Outside of this sub-sub specialization, a significant portion of my practice is also devoted to the care of a broad range of ?general gastroenterology? concerns.
Functional, motility, esophageal, and general gastroenterology disorders are very common, and can cause significant disability. Some examples include irritable bowel syndrome, functional dyspepsia, gastroparesis, chronic nausea, chronic constipation, achalasia, and gastroesophageal reflux disease.
Despite the common nature of these disorders, many are not well understood, leading to frustration among both patients and clinicians alike. Furthermore, there is an incorrect stigma associated with some of these disorders that ?it is all in your head.? On the opposite side of the spectrum, there is sometimes an incorrect assumption that we will be able to pinpoint an exact underlying cause in all cases, but this is not possible with current technology. We aim to bridge this gap using the latest diagnostic testing and treatment paradigms, as well as a healing hand. Additionally, our group is actively engaged in multiple research projects and studies to drive the future of the field.
Though I am early in my career, I am hoping that by the end the field will look nothing like it does today. I am hopeful, and I believe that we can revolutionize the field to better characterize gastrointestinal disorders, and come up with highly effective targeted treatments.
Professor of Medicine (Infectious Diseases) at the Stanford University Medical Center, Emeritus
Current Research and Scholarly Interests Dr. Zolopa’s research applies a variety of clinical epidemiologic methods in an effort to optimize antiretroviral therapy and understand the impact of drug resistance on response to ARV. Areas of focus include the clinical application of resistance testing in optimizing antiretroviral therapy, clinical cohorts, trials of antiretroviral therapies and population-based epidemiologic evaluation of HIV resistance and efficacy of ARV therapy. More recently studies focused on premature aging in HIV.
Assistant Professor of Biomedical Data Science and, by courtesy, of Computer Science and of Electrical Engineering
Current Research and Scholarly Interests My group works on both foundations of statistical machine learning and applications in biomedicine and healthcare. We develop new technologies that make ML more accountable to humans, more reliable/robust and reveals core scientific insights.
We want our ML to be impactful and beneficial, and as such, we are deeply motivated by transformative applications in biotech and health. We collaborate with and advise many academic and industry groups.
J. Bradley Zuchero
Assistant Professor of Neurosurgery
Current Research and Scholarly Interests Glia are a frontier of neuroscience, and overwhelming evidence from the last decade shows that they are essential regulators of all aspects of the nervous system. The Zuchero Lab aims to uncover how glial cells regulate neural development and how their dysfunction contributes to diseases like multiple sclerosis (MS) and in injuries like stroke.
Although glia represent more than half of the cells in the human brain, fundamental questions remain to be answered. How do glia develop their highly specialized morphologies and interact with neurons to powerfully control form and function of the nervous system? How is this disrupted in neurodegenerative diseases and after injury? By bringing cutting-edge cell biology techniques to the study of glia, we aim to uncover how glia help sculpt and regulate the nervous system and test their potential as novel, untapped therapeutic targets for disease and injury.
We are particularly interested in myelin, the insulating sheath around neuronal axons that is lost in diseases like MS. How do oligodendrocytes- the glial cell that produces myelin in the central nervous system- form and remodel myelin, and why do they fail to regenerate myelin in disease? Our current projects aim to use cell biology and neuroscience approaches to answer these fundamental questions. Ultimately we hope our work will lead to much-needed therapies to promote remyelination in patients.
Clinical Associate Professor, Radiology - Pediatric Radiology
Bio Dr. Zucker is a board-certified pediatric and cardiovascular radiologist with a special interest in CT and MRI for congenital heart disease.
Assistant Professor of Medicine (General Medical Disciplines)
Current Research and Scholarly Interests - Improving care and supporting self-management for patients with multiple chronic conditions
- Designing and evaluating innovative health care delivery models for complex and costly patients
- Optimizing health-related technology to personalize and improve care for complex patients and their caregivers
Assistant Professor of Neurosurgery at the Stanford University Medical Center
Current Research and Scholarly Interests My goal is to translate research into real-world action and decision-making so that my work can impact patients and the institutions in which they receive care. With a research focus on healthcare cost and quality of care, I approach neurosurgery in a unique way?one that applies business operations, economics, and healthcare delivery principles to our field. I have pursued formal LEAN business training, and believe in the importance of working together with other departments and administrators, as well as physicians and surgeons on the hospital and national level, to effect change. During my residency, I developed and led a multi-departmental prospective study at UCSF called OR SCORE (OR Surgical Cost Reduction Project) that brought together surgeons from the neurosurgery, orthopedics and ENT departments with nurses and administrators. OR SCORE successfully reduced surgical supply costs by nearly one million dollars in its first year by providing >60 surgeons with price transparency scorecards. This work led to a first-author publication in JAMA Surgery, but more importantly, set the foundation for further quality improvement and cost reduction efforts across the UCSF hospital system.
A volunteer neurosurgical mission trip to Guadalajara, Mexico, where limited resources create an OR environment that is strikingly more frugal than the U.S., inspired me to lead another project aimed at quantifying and reducing operating room waste at UCSF. I have also conducted research looking at the safety and outcomes of overlapping surgery, as well as several projects to define the factors underlying variation in cost for neurosurgical care using UCSF?s hospital data and national databases like the National Inpatient Sample, Vizient (formerly known as University Health Consortium), and Medicare.
As a clinical fellow at Johns Hopkins, I continued and expanded these research efforts. I designed and implemented an Enhanced Recovery after Surgery (ERAS) protocol at the Johns Hopkins Bayview hospital. This protocol standardized care for our spine patients, emphasizing pre-operative rehabilitation, psychiatric and nutritional assessments, and smoking cessation, as well as intra- and post-operative multi-modal pain therapy, early mobilization, and standardized antibiotic and bowel regimens. I also collaborated with engineers in the Johns Hopkins Carnegie Center for Surgical Innovation to develop better algorithms for intra-operative CT imaging, and provided assistance with operations to a basic science study looking at the role of cerebrospinal fluid drainage and duraplasty in a porcine model of spinal cord injury.
At Stanford, I am building a research group focused on: (1) perfecting paradigms for delivery of high-end technology in spinal care, including robotics and navigation, (2) implementing cost and quality strategies in large healthcare systems, and (3) computational analysis of big-data to effect real-time risk stratification and decision making in spine surgery. I'm excited to collaborate with my peers across surgical and medical departments, as well as business and engineering colleagues.