School of Medicine


Showing 81-90 of 93 Results

  • Francesca Briganti

    Francesca Briganti

    Postdoctoral Research Fellow, Cardiovascular Institute

    Current Research and Scholarly Interests One gene can lead to the production of many different RNA isoforms via mechanisms such as alternative promoter usage, splicing, and polyadenylation. The functional significance of many of these isoforms, their impact on cell physiology, and their regulation remain mostly controversial. Understanding the functional consequences of transcript heterogeneity will improve our understanding of gene expression regulation, broadening our ability to intervene when mutations that interfere with this regulation cause human disease.
    My goal is to become an independent researcher leading an academic lab that focuses on better understanding human tissue-specific post-transcriptional regulation of gene expression and developing mechanism-based therapeutics. My general strategy is to study the function of regulatory genes and their deregulation in human disease. My specific approach is to understand the molecular mechanisms by which disease-causing mutations alter the gene function and lead to human disease. My hypothesis is that a detailed understanding of the relationship between the gene's molecular function and the disease mechanism will allow the development of first-in-class, personalized therapeutic strategies that target the disease mechanisms rather than manage symptoms independently of disease etiology.

  • Edith Brignoni Perez

    Edith Brignoni Perez

    Postdoctoral Research Fellow, Psychiatry

    Bio Edith Brignoni Pérez completed her Ph.D. in Neuroscience at Georgetown University in June 2019. Her doctoral work focused on investigating the neurofunctional bases of reading in bilingual-biliterate children and adults, under the mentorship of Dr. Guinevere F. Eden at the Center for the Study of Learning. Edith used functional magnetic resonance imaging to investigate whether bilinguals rely on a different functional brain system to read words in English compared (1) to monolinguals and (2) to reading words in Spanish.

    She joined the Developmental-Behavioral Pediatrics research unit in July 2019 as a postdoctoral fellow co-advised by Drs. Katherine E. Travis (Pediatrics), Heidi M. Feldman (Pediatrics), and Ian Gotlib (Psychology). Some of Edith?s current research interests include how the brain?s white matter microstructure and developmental outcomes relate to one another, particularly in infants born prematurely. She is also interested in changes to brain structure and function following early intervention of language exposure, and long-term neurodevelopmental outcomes relationship with early-life stress.

  • Andrew Brooks

    Andrew Brooks

    Postdoctoral Research Fellow, Genetics

    Bio Postdoctoral researcher in the Snyder Lab. My research focuses on the human gut microbiome, and I am involved in multiple multiomic projects investigating how physiological systems through the human body interact across different lifestyles and health states. I perform both wet and dry lab aspects of multiomics analyses, and am involved in two coronavirus research projects including handling of positive SARS-COV-2 samples.

  • Lisa Bruckert

    Lisa Bruckert

    Postdoctoral Research Fellow, Neonatal and Developmental Medicine

    Current Research and Scholarly Interests Cerebellar Circuitry in Development, Learning, and Clinical Conditions: While many recent studies document the importance of cerebral white matter circuitry in human development and learning, it remains unclear how circuits that connect cerebellum to the rest of the brain change with age, experience, and disease. I am interested in examining the white matter circuitry of the human cerebellum in normal development and in relation to healthy and disordered cognitive functioning.

  • Christine Mai-Anh Bui

    Christine Mai-Anh Bui

    Postdoctoral Medical Fellow, Cardiology

    Current Research and Scholarly Interests Along with my internal medicine and pediatrics background, I have always been interested in palliative care and end of life. I would like to apply these interests to pediatric cardiology and adult congenital cardiology, as these patients often are critically or chronically ill, and would benefit from a palliative care perspective.

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