Brian Nuyen studied General Biology and Music at Revelle College at University of California, San Diego (UCSD), where he was also a member of the UCSD Medical Scholars Program, a combined B.S./M.D program. At UCSD School of Medicine, Brian discovered his passion for otitis media and language/communication sciences, leading to a Division of Otolaryngology Research Fellowship at UCSD School of Medicine and subsequent Howard Hughes Medical Institute (HHMI) Student Medical Research Fellowship. During his time in medical school, Brian explored diversity health interests, focusing on minority health education and equality, including lesbian, gay, bisexual, and transgender health. He continued these interests as an otolaryngology-head and neck surgery resident at Stanford, as a founding member and social chair of the Stanford Graduate Medical Education Diversity Committee. He currently serves as Stanford Residency Program representative to the American Academy of Otolaryngology-Head and Neck Surgery/Foundation (AAO-HNS/F).

Clinical Focus

  • Residency
  • Otolaryngology-Head and Neck Surgery

Honors & Awards

  • Resident Leadership Grant, AAO-HNS/F Board of Governors/Leadership Forum Spring Meeting 2017 (March 2017)
  • Howard Hughes Medical Institute Medical Fellow Keynote Speaker, Howard Hughes Medical Institute Medical Research Fellowship 2015-2016 (2016)
  • Clinical Honors ? Otology, Otolaryngology, University of California, San Diego School of Medicine (2012-2013)
  • Medical Scholars Combined Degree Program, University of California, San Diego School of Medicine (2006-2010)

Boards, Advisory Committees, Professional Organizations

  • Stanford Residency Program Representative, Academy of Otolaryngology-Head and Neck Surgery/Foundation (2016 - Present)
  • Regional Representative ? Arizona, California, Hawaii, Nevada, Academy of Otolaryngology-Head and Neck Surgery/Foundation (2016 - Present)
  • Resident Member, AO CMF - ? Arbeitsgemeinschaft für Osteosynthesefragen Craniomaxillofacial (2016 - Present)
  • Resident Member, American Academy of Otolaryngic Allergy (2016 - Present)
  • Social Chair, Stanford Graduate Medical Education Diversity Committee (2016 - Present)
  • Member, International Society for Otitis Media (2015 - 2017)
  • Co-Chair, West Coast Region, HHMI Medical Research Fellowship (2014 - 2016)
  • Associate Member, History of Otolaryngology Committee Member, Association of Research in Otolaryngology (2014 - Present)
  • Member, Gold Humanism Honor Society, Arnold P. Gold Foundation (2013 - Present)
  • Member, Phi Beta Kappa Honor Society (2008 - Present)

Professional Education

  • Doctor of Medicine, University of California, San Diego School of Medicine, Medicine (2016)
  • Research Fellow, Howard Hughes Medical Student Medical Research Fellowship, Otitis Media (2015)
  • Bachelor of Science, Revelle College - University of California, San Diego, General Biology (2010)


All Publications

  • Dysphagia and Pharyngeal Obstruction in a Nonsmoker JAMA OTOLARYNGOLOGY-HEAD & NECK SURGERY Nuyen, B. A., Berry, G., Megwalu, U. 2018; 144 (2): 171?72

    View details for PubMedID 29222562

  • Outcomes in Head and Neck Resections That Require Multiple-Flap Reconstructions: A Systematic Review. JAMA otolaryngology-- head & neck surgery Gao, R. W., Nuyen, B. A., Divi, V., Sirjani, D., Rosenthal, E. L. 2018


    Complex head and neck cancer defects that require multiflap reconstructions are technically feasible, but the morbidity and patient outcomes of such large-scale head and neck operations have yet to be systematically reviewed.To systematically review existing literature to characterize the outcomes of large-scale head and neck resections that require multiple-flap reconstructions (defined as defects that require >1 flap [free, pedicled, or combinations thereof]).Two authors independently searched PubMed, Embase, and the Cochrane Review databases for English-only texts published on any date. Included studies examined patients who underwent complex head and neck surgical resections that required multiple simultaneous flaps for reconstruction. Included studies reported results on at least one of the following outcomes: functional and aesthetic, patient survival, or cost (estimated by operating room time, length of stay, and/or complications). Methodological Index for Non-Randomized Studies (MINORS) criteria for bias and modified Oxford Centre for Evidence-Based Medicine recommendations were used to assess study quality.Twenty-four studies published from November 1, 1992, through September 1, 2016, met the final inclusion criteria, with a total of 487 patients (370 male [79.4%]; mean [SD] weighted age, 55.1 [4.1] years). Sixty-two of 250 patients (24.8%) were partially or fully dependent on feeding tubes at follow-up. Twenty-two of 75 patients (29.3%) had poor postoperative oral competence, causing moderate to severe drooling. Nineteen of 108 patients (17.6%) had unintelligible speech. Nine of 64 patients (14.1%) were unsatisfied with their aesthetic outcome. The mean (SD) reported survival was 2.36?(1.39) years. The mean (SD) length of stay was 24.5 (12.2) days in 219 patients. Eighty-eight minor complications (eg, partial flap necrosis, donor site complications) and 185 major complications (eg, surgical reexplorations, flap loss, or cardiopulmonary complications) were reported in 380 patients. Mean (SD) MINORS scores were 16.0 (3.2) for comparison studies and 11.4 (1.8) for noncomparison studies.Because of limited patient life expectancies, modest functional and aesthetic outcomes, and significant associated costs, surgeons should weigh the curative potential and palliative benefits for individual patients with a comprehensive view of the overall outcomes of extensive head and neck resections and reconstructions. Realistic expectations should be emphasized during preoperative discussions with patients.

    View details for PubMedID 29978196

  • Survival Outcomes in Oropharyngeal Small-Cell Carcinoma Compared With Squamous Cell Carcinoma: A Population-based Study. JAMA otolaryngology-- head & neck surgery Megwalu, U. C., Nuyen, B. A. 2017

    View details for DOI 10.1001/jamaoto.2017.0025

    View details for PubMedID 28301632

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