Bio

Bio


I attended primary and secondary school in Houston, TX, USA. I attended The University of Texas - Austin from 2001-2005 where I double-majored in Electrical Engineering and in Physics. Afterward, I work at Harris Stratex Corporation as a quality control engineer in electronics manufacturing. I entered graduate school in 2007 at The University of Texas, MD Anderson Cancer Center where I earned a Ph.D. in Medical Physics.

I work on the early research and development of biomedical technology. I am primarily interested in the intersection of Physics, Electrical Engineering, and Biomedical Engineering. My objective is to develop new medical and electronic technologies, especially in biomedical imaging, and improve the diagnosis and treatment of disease.

Professional Education


  • Doctor of Philosophy, UnivTexasBiomedicalSciences (2012)
  • Bachelor of Science, University of Texas Austin (2005)

Stanford Advisors


Research & Scholarship

Lab Affiliations


Publications

Journal Articles


  • L-shell x-ray fluorescence computed tomography (XFCT) imaging of Cisplatin PHYSICS IN MEDICINE AND BIOLOGY Bazalova, M., Ahmad, M., Pratx, G., Xing, L. 2014; 59 (1): 219-232

    Abstract

    X-ray fluorescence computed tomography (XFCT) imaging has been focused on the detection of K-shell x-rays. The potential utility of L-shell x-ray XFCT is, however, not well studied. Here we report the first Monte Carlo (MC) simulation of preclinical L-shell XFCT imaging of Cisplatin. We built MC models for both L- and K-shell XFCT with different excitation energies (15 and 30 keV for L-shell and 80 keV for K-shell XFCT). Two small-animal sized imaging phantoms of 2 and 4 cm diameter containing a series of objects of 0.6 to 2.7 mm in diameter at 0.7 to 16 mm depths with 10 to 250 µg mL(-1) concentrations of Pt are used in the study. Transmitted and scattered x-rays were collected with photon-integrating transmission detector and photon-counting detector arc, respectively. Collected data were rearranged into XFCT and transmission CT sinograms for image reconstruction. XFCT images were reconstructed with filtered back-projection and with iterative maximum-likelihood expectation maximization without and with attenuation correction. While K-shell XFCT was capable of providing an accurate measurement of Cisplatin concentration, its sensitivity was 4.4 and 3.0 times lower than that of L-shell XFCT with 15 keV excitation beam for the 2 cm and 4 cm diameter phantom, respectively. With the inclusion of excitation and fluorescence beam attenuation correction, we found that L-shell XFCT was capable of providing fairly accurate information of Cisplatin concentration distribution. With a dose of 29 and 58 mGy, clinically relevant Cisplatin Pt concentrations of 10 µg mg(-1) could be imaged with L-shell XFCT inside a 2 cm and 4 cm diameter object, respectively.

    View details for DOI 10.1088/0031-9155/59/1/219

    View details for Web of Science ID 000328549200011

    View details for PubMedID 24334507

  • Defining internal target volume using positron emission tomography for radiation therapy planning of moving lung tumors JOURNAL OF APPLIED CLINICAL MEDICAL PHYSICS Riegel, A. C., Bucci, M. K., Mawlawi, O. R., Ahmad, M., Luo, D., Chandler, A., Pan, T. 2014; 15 (1): 279-289

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