Current Research and Scholarly Interests
The human placentas are readily available and represent a rich source of novel extraembryonic mesodermal stem cell (hAMSCs) population from young healthy donors. The human amniotic mesenchymal stem cells (hAMSCs) are situated at the maternal-fetal border of the placenta and demonstrate unique characteristics, including partial pluripotency, cardiac progenitor phenotype, and immunoprivelege. These features enable universal cardiovascular cell therapy.
I would like to identify the optimal stem cell population for myocardial restoration.
Main focus of my research during my post-doctoral fellowship are
1) modify the immunomodulatory properties of stem cells
2) establish robust tissue engineering platform
3) assess stem cell engraftment/survival and myocardial function using BLI/cellular and molecular MRI