School of Medicine
Showing 51-100 of 276 Results
Rajesh Dash, MD PhD; Director of SSATHI & CardioClick
Associate Professor of Medicine (Cardiovascular Medicine) at the Stanford University Medical Center
Current Research and Scholarly Interests I have two research areas:
1) Heart disease in South Asians - genetic, metabolic, & behavioral underpinnings of an aggressive phenotype.
2) Imaging cell injury & recovery in the heart. Using Cardiac MRI to visualize signals of early injury and facilitating preventive medical therapy. Optimizing new imaging methods for viable cells to delineate live heart cells or transplanted stem cells.
Mark M. Davis
Director, Stanford Institute for Immunity, Transplantation and Infection and the Burt and Marion Avery Family Professor
Current Research and Scholarly Interests Molecular mechanisms of lymphocyte recognition and differentiation; Systems immunology and human immunology; vaccination and infection.
Vinicio de Jesus Perez MD
Associate Professor of Medicine (Pulmonary and Critical Care Medicine)
Current Research and Scholarly Interests My work is aimed at understanding the molecular mechanisms involved in the development and progression of pulmonary arterial hypertension (PAH). I am interested in understanding the role that the BMP and Wnt pathways play in regulating functions of pulmonary endothelial and smooth muscle cells both in health and disease.
Professor of Radiology (Canary Cancer Center)
Bio Dr. Demirci is currently a Professor with tenure at Stanford University School of Medicine and Principal Investigator of the Demirci Bio-Acoustic MEMS in Medicine (BAMM) Lab at the Canary Center at Stanford for Cancer Early Detection. He received his B.S. degree in Electrical Engineering in 1999 as a James B. Angell Scholar (summa cum laude) from University of Michigan, Ann Arbor. He received his M.S. degree in 2001 in Electrical Engineering, M.S. degree in Management Science and Engineering in 2005, and Ph.D. in Electrical Engineering in 2005, all from Stanford University.
BAMM Lab specializes in applying micro- and nanoscale technologies to problems in medicine and early cancer detection at the interface between micro/nanoscale engineering and medicine. Our goal is to apply innovative technologies to clinical problems. Our major research theme focuses on creating new microfluidic technology platforms targeting broad applications in medicine. In this interdisciplinary space at the convergence of engineering, biology and materials science, we create novel technologies for disposable point-of-care (POC) diagnostics and monitoring of infectious diseases, cancer and controlling cellular microenvironment in nanoliter droplets for biopreservation and microscale tissue engineering applications. These applications are unified around our expertise to test the limits of cell manipulation by establishing microfluidic platforms to provide solutions to real world problems at the clinic.
Our lab creates technologies to manipulate cells in nanoliter volumes to enable solutions for real world problems in medicine including applications in infectious disease diagnostics and monitoring for global health, cancer early detection, cell encapsulation in nanoliter droplets for cryobiology, and bottom-up tissue engineering. Dr. Demirci has published over 120 peer reviewed publications in journals including PNAS, Nature Communications, Advanced Materials, Small, Trends in Biotechnology, Chemical Society Reviews and Lab-chip, over 150 conference abstracts and proceedings, 10+ book chapters, and an edited book. His work was highlighted in Wired Magazine, Nature Photonics, Nature Medicine, MIT Technology Review, Reuters Health News, Science Daily, AIP News, BioTechniques, and Biophotonics. He is fellow-elect of the American Institute of Biological and Medical Engineering (AIMBE, 2017). His scientific work has been recognized by numerous national and international awards including the NSF Faculty Early Career Development (CAREER) Award (2012), the IEEE-EMBS Early Career Achievement Award (2012), Scientist of the year award from Stanford radiology Department (2017). He was selected as one of the world?s top 35 young innovators under the age of 35 (TR-35) by the MIT Technology Review at the age of 28. In 2004, he led a team that won the Stanford University Entrepreneur?s Challenge Competition and Global Start-up Competition in Singapore. His work has been translated to start-up companies including DxNow, KOEK Biotechnology and LEVITAS. There has been over 10,000 live births in the US, Europe, Asia, and Middle East using the sperm selection technology that came out of Dr. Demirci's lab.
Gundeep Dhillon, MD, MPH
Associate Professor of Medicine (Pulmonary and Critical Care Medicine) at the Stanford University Medical Center
Current Research and Scholarly Interests 1. Use of an administrative database (UNOS) to study lung transplant outcomes.
2. Expression of the plasminogen activator inhibitor (PAI) 1 antibody in peripheral blood after lung transplantation and its association with bronchiolitis obliterans syndrome (chronic rejection).
3. Impact of airway hypoxia, due to lack of bronchial circulation, on long-term lung transplant outcomes.
4. CMV specific T-cell immunity in lung transplant recipients and its impact on acute rejection.
Professor of Pediatrics (Pediatric Cardiology) at the Lucile Salter Packard Children's Hospital
Current Research and Scholarly Interests Arrhythmia management in pediatric heart failure, especially resynchronization therapy in congenital heart disease,Radio frequency catheter ablation of pediatric arrhythmias,
Associate Professor of Chemical Engineering
Current Research and Scholarly Interests My lab is deeply interested in uncovering the physical principles that underlie the construction of complex, multicellular animal life.
Assistant Professor (Research) of Radiology (Molecular Imaging Program at Stanford)
Current Research and Scholarly Interests Dr. Durmus' research focuses on applying micro/nano-technologies to investigate cellular heterogeneity for single-cell analysis and personalized medicine. At Stanford, she is developing platform technologies for sorting and monitoring cells at the single-cell resolution. This magnetic levitation-based technology is used for wide range of applications in medicine, such as, label-free detection of circulating tumor cells (CTCs) from blood; high-throughput drug screening; and rapid detection and monitoring of antibiotic resistance in real-time. During her PhD, she has engineered nanoparticles and nanostructured surfaces to decrease antibiotic-resistant infections.
Daniel Bruce Ennis
Associate Professor of Radiology (Veterans Affairs)
Bio Daniel Ennis (Ph.D.) is an Associate Professor in the Department of Radiology. As an MRI scientist for nearly twenty years, he has worked to develop advanced translational cardiovascular MRI methods for quantitatively assessing structure, function, flow, and remodeling in both adult and pediatric populations. He began his research career as a Ph.D. student in the Department of Biomedical Engineering at Johns Hopkins University during which time he formed an active collaboration with investigators in the Laboratory of Cardiac Energetics at the National Heart, Lung, and Blood Institute (NIH/NHLBI). Thereafter, he joined the Departments of Radiological Sciences and Cardiothoracic Surgery at Stanford University as a post doc and began to establish an independent research program with an NIH K99/R00 award focused on ?Myocardial Structure, Function, and Remodeling in Mitral Regurgitation.? For ten years he led a group of clinicians and scientists at UCLA working to develop and evaluate advanced cardiovascular MRI exams as PI of several NIH funded studies. In 2018 he returned to Stanford Radiology and the Radiological Sciences Lab to bolster programs in cardiovascular MRI. He is also the Director of Radiology Research for the Veterans Administration Palo Alto Health Care System where he oversees a growing radiology research program.
Professor of Cardiothoracic Surgery (Adult Cardiac Surgery) at the Stanford University Medical Center
Current Research and Scholarly Interests Cardiac surgery education and simulation-based learning, coronary artery bypass surgery, cardiac valve disease
William Fearon, MD
Professor of Medicine (Cardiovascular Medicine) at the Stanford University Medical Center
Current Research and Scholarly Interests Dr. Fearon's general research interest is coronary physiology. In particular, he is investigating invasive methods for evaluating the coronary microcirculation. His research is currently funded by an NIH R01 Award.
Jeffrey A. Feinstein, MD, MPH
Dunlevie Family Professor of Pulmonary Vascular Disease and Professor, by courtesy, of Bioengineering at the Lucile Salter Packard Children's Hospital
Current Research and Scholarly Interests Research interests include (1) computer simulation and modeling of cardiovascular physiology with specific attention paid to congenital heart disease and its treatment, (2) the evaluation and treatment of pulmonary hypertension/pulmonary vascular diseases, and (3) development and testing of medical devices/therapies for the treatment of congenital heart disease and pulmonary vascular diseases.
Associate Professor of Cardiothoracic Surgery (Adult Cardiac Surgery) at the Stanford University Medical Center
Current Research and Scholarly Interests Molecular and genetic mechanisms of aortic aneurysm/dissection development. Molecular mechanisms of aneurysm formation in Marfan Syndrome. Clinical research interests include thoracic aortic diseases (aneurysms, dissections).
Professor of Radiology (Cardiovascular Imaging) at the Stanford University Medical Center
Current Research and Scholarly Interests Non-invasive Cardiovascular Imaging
Contrast Medium Dynamics
Michael B. Fowler, MB, FRCP
Professor of Medicine (Cardiovascular) at the Stanford University Medical Center
Current Research and Scholarly Interests Adrenergic nervous system; beta-adrenergic function in, heart failure; drugs in heart failure.
W. M. Keck, Sr. Professor in Engineering and Professor, by court, of Materials Science and Engineering
Bio The properties of ultrathin polymer films are often different from their bulk counterparts. We use spin casting, Langmuir-Blodgett deposition, and surface grafting to fabricate ultrathin films in the range of 100 to 1000 Angstroms thick. Macromolecular amphiphiles are examined at the air-water interface by surface pressure, Brewster angle microscopy, and interfacial shear measurements and on solid substrates by atomic force microscopy, FTIR, and ellipsometry. A vapor-deposition-polymerization process has been developed for covalent grafting of poly(amino acids) from solid substrates. FTIR measurements permit study of secondary structures (right and left-handed alpha helices, parallel and anti-parallel beta sheets) as a function of temperature and environment.
A broadly interdisciplinary collaboration has been established with the Department of Ophthalmology in the Stanford School of Medicine. We have designed and synthesized a fully interpenetrating network of two different hydrogel materials that have properties consistent with application as a substitute for the human cornea: high water swellability up to 85%,tensile strength comparable to the cornea, high glucose permeability comparable to the cornea, and sufficient tear strength to permit suturing. We have developed a technique for surface modification with adhesion peptides that allows binding of collagen and subsequent growth of epithelial cells. Broad questions on the relationships among molecular structure, processing protocol, and biomedical device application are being pursued.
Fletcher Jones II Professor in the School of Engineering
Bio The processing of complex liquids (polymers, suspensions, emulsions, biological fluids) alters their microstructure through orientation and deformation of their constitutive elements. In the case of polymeric liquids, it is of interest to obtain in situ measurements of segmental orientation and optical methods have proven to be an excellent means of acquiring this information. Research in our laboratory has resulted in a number of techniques in optical rheometry such as high-speed polarimetry (birefringence and dichroism) and various microscopy methods (fluorescence, phase contrast, and atomic force microscopy).
The microstructure of polymeric and other complex materials also cause them to have interesting physical properties and respond to different flow conditions in unusual manners. In our laboratory, we are equipped with instruments that are able to characterize these materials such as shear rheometer, capillary break up extensional rheometer, and 2D extensional rheometer. Then, the response of these materials to different flow conditions can be visualized and analyzed in detail using high speed imaging devices at up to 2,000 frames per second.
There are numerous processes encountered in nature and industry where the deformation of fluid-fluid interfaces is of central importance. Examples from nature include deformation of the red blood cell in small capillaries, cell division and structure and composition of the tear film. Industrial applications include the processing of emulsions and foams, and the atomization of droplets in ink-jet printing. In our laboratory, fundamental research is in progress to understand the orientation and deformation of monolayers at the molecular level. These experiments employ state of the art optical methods such as polarization modulated dichroism, fluorescence microscopy, and Brewster angle microscopy to obtain in situ measurements of polymer films and small molecule amphiphile monolayers subject to flow. Langmuir troughs are used as the experimental platform so that the thermodynamic state of the monolayers can be systematically controlled. For the first time, well characterized, homogeneous surface flows have been developed, and real time measurements of molecular and microdomain orientation have been obtained. These microstructural experiments are complemented by measurements of the macroscopic, mechanical properties of the films.
Margaret T. Fuller
Reed-Hodgson Professor in Human Biology and Professor of Genetics and of Obstetrics/Gynecology (Reproductive and Stem Cell Biology)
Current Research and Scholarly Interests Regulation of self-renewal, proliferation and differentiation in adult stem cell lineages. Developmental tumor suppressor mechanisms and regulation of the switch from proliferation to differentiation. Cell type specific transcription machinery and regulation of cell differentiation. Developmental regulation of cell cycle progression during male meiosis.
Sanjiv Sam Gambhir, MD, PhD
Current Research and Scholarly Interests My laboratory focuses on merging advances in molecular biology with those in biomedical imaging to advance the field of molecular imaging. Imaging for the purpose of better understanding cancer biology and applications in gene and cell therapy, as well as immunotherapy are all being studied. A key long-term focus is the earlier detection of cancer by combining in vitro diagnostics and molecular imaging.
Rehnborg Farquhar Professor
Current Research and Scholarly Interests The role of nutrition in individual and societal health, with particular interests in: plant-based diets, differential response to low-carb vs. low-fat weight loss diets by insulin resistance status, chronic disease prevention, randomized controlled trials, human nutrition, community based studies, Community Based Participatory Research, sustainable food movement (animal rights and welfare, global warming, human labor practices), stealth health, nutrition policy, nutrition guidelines
Paul George, MD, PhD
Assistant Professor of Neurology and, by courtesy, of Neurosurgery at the Stanford University Medical Center
Current Research and Scholarly Interests CONDUCTIVE POLYMER SCAFFOLDS FOR STEM CELL-ENHANCED STROKE RECOVERY:
We focus on developing conductive polymers for stem cell applications. We have created a microfabricated, polymeric system that can continuously interact with its biological environment. This interactive polymer platform allows modifications of the recovery environment to determine essential repair mechanisms. Recent work studies the effect of electrical stimulation on neural stem cells seeded on the conductive scaffold and the pathways by which it enhances stroke recovery Further understanding the combined effect of electrical stimulation and stem cells in augmenting neural repair for clinical translational is a major focus of this research going forward.
BIOPOLYMER SYSTEMS FOR NEURAL RECOVERY AND STEM CELL MODULATION:
The George lab develops biomaterials to improve neural recovery in the peripheral and central nervous systems. By controlled release of drugs and molecules through biomaterials we can study the temporal effect of these neurotrophic factors on neural recovery and engineer drug delivery systems to enhance regenerative effects. By identifying the critical mechanisms for stroke and neural recovery, we are able to develop polymeric technologies for clinical translation in nerve regeneration and stroke recovery. Recent work utilizing these novel conductive polymers to differentiate stem cells for therapeutic and drug discovery applications.
APPLYING ENGINEERING TECHNIQUES TO DETERMINE BIOMARKERS FOR STROKE DIAGNOSTICS:
The ability to create diagnostic assays and techniques enables us to understand biological systems more completely and improve clinical management. Previous work utilized mass spectroscopy proteomics to find a simple serum biomarker for TIAs (a warning sign of stroke). Our study discovered a novel candidate marker, platelet basic protein. Current studies are underway to identify further candidate biomarkers using transcriptome analysis. More accurate diagnosis will allow for aggressive therapies to prevent subsequent strokes.
Assistant Professor of Medicine (Biomedical Informatics) and of Biomedical Data Science
Current Research and Scholarly Interests My lab focuses on biomedical data fusion: the development of machine learning methods for biomedical decision support using multi-scale biomedical data. We primarily use methods based on regularized linear regression to accomplish this. We primarily focus on applications in oncology and neuroscience.
Mary Kane Goldstein
Professor of Medicine (Center for Primary Care and Outcomes Research) at the Palo Alto Veterans Affairs Health Care System
Current Research and Scholarly Interests Health services research in primary care and geriatrics: developing, implementing, and evaluating methods for clinical quality improvement. Current work includes applying health information technology to quality improvement through clinical decision support (CDS) integrated with electronic health records; encoding clinical knowledge into computable formats in automated knowledge bases; natural language processing of free text in electronic health records; analyzing multiple comorbidities
Eric R. Gross
Assistant Professor of Anesthesiology, Perioperative and Pain Medicine
Current Research and Scholarly Interests A part of the laboratory studies organ injury and how common genetic variants may affect the response to injury caused by surgery; particularly aldehydes. Aldehyde accumulation can cause many post-operative complications that people experience during surgery- whether it be reperfusion injury, post-operative pain, cognitive dysfunction, or nausea. The other part of the lab studies the impact of e-cigarettes and alcohol, when coupled with genetics, on the cardiopulmonary system.
Professor of Psychology
Current Research and Scholarly Interests I am interested in emotion and emotion regulation. My research employs behavioral, physiological, and brain measures to examine emotion-related personality processes and individual differences. My current interests include emotion coherence, specific emotion regulation strategies (reappraisal, suppression), automatic emotion regulation, and social anxiety.
Johnson & Johnson Professor of Surgery and Professor, by courtesy, of Bioengineering and of Materials Science and Engineering
Current Research and Scholarly Interests Geoffrey Gurtner's Lab is interested in understanding the mecahnism of new blood vessel growth following injury and how pathways of tissue regeneration and fibrosis interact in wound healing.
Lawrence Crowley, M.D., Endowed Professor in Child Health
Current Research and Scholarly Interests His research and clinical work focuses on the development of interventional techniques for fetal and neonatal treatment of congenital heart disease, pulmonary, vascular physiology, and the neurologic impact of open-heart surgery. He developed and pioneered the ôunifocalizationö procedure, in which a single procedure is used to repair a complex and life-threatening congenital heart defect rather than several staged open-heart surgeries as performed by other surgeons.
Arthur L. Bloomfield Professor of Medicine
Bio Dr. Robert A. Harrington is an interventional cardiologist and the Arthur L. Bloomfield Professor of Medicine and Chairman of the Department of Medicine at Stanford University. Dr. Harrington was previously the Richard Sean Stack, MD Distinguished Professor and the Director of the Duke Clinical Research Institute (DCRI) at Duke University. His research interests include evaluating antithrombotic therapies to treat acute ischemic heart disease and to minimize the acute complications of percutaneous coronary procedures, studying the mechanism of disease of the acute coronary syndromes, understanding the issue of risk stratification in the care of patients with acute ischemic coronary syndromes, building local, national and international collaborations for the efficient conduct of innovative clinical research and trying to better understand and improve upon the methodology of clinical research. His research has been extensively funded through NIH, NIA, other peer reviewed agencies and private industry. Committed to training and mentorship, Harrington has served as the principal mentor for more than 20 post-doctoral clinical research fellows focused on cardiovascular research.
He has authored more than 640 peer-reviewed manuscripts, reviews, book chapters, and editorials. Thomson Reuters lists him as one of the most cited investigators in clinical medicine from 2002-2014. He is a deputy editor of JAMA Cardiology and an editorial board member for the Journal of the American College of Cardiology. He has served as editor of five textbooks and is a senior editor of the 13th and 14th editions of Hurst?s The Heart, one of the leading textbooks of cardiovascular medicine. He has been a member of the NHLBI?s Clinical Trials Study Section and the IOM?s Working Group on Data Sharing. He served as a member of the NIH NCATS Advisory Council Working Group on the IOM CTSA Program. He recently served a second term as a member and the chair of the US Food and Drug Administration Cardiovascular and Renal Drugs Advisory Committee.
Harrington was recently a member of the American College of Cardiology (ACC) Board of Trustees and is currently a member of the American Heart Association?s (AHA) Board of Directors, its Science Advisory and Coordinating Committee, and its President-elect. He will serve as the AHA President beginning in July 2019. He served as the Chair for the AHA?s Scientific Sessions in 2013 and 2014. Harrington is a Fellow of the American College of Cardiology, the American Heart Association, the Society for Cardiac Angiography and Intervention, the European Society of Cardiology, the American College of Chest Physicians and the American College of Physicians. He is an elected member of the Association of American Physicians and the Association of University Cardiologists. In 2015, he was elected to membership in the National Academy of Medicine/Institute of Medicine. In 2016, he was named a Master of the American College of Cardiology. He was awarded the AHA's Clinical Research Prize in 2017.
Harrington received his BA in English at the College of the Holy Cross, Worcester, MA. He attended Dartmouth Medical School and received his MD from Tufts University School of Medicine, Boston MA. He did his internship, residency and served as the chief resident in internal medicine at the University of Massachusetts Medical Center, Worcester MA. He trained in cardiology, interventional cardiology and clinical research (Duke Databank for Cardiovascular Disease) at Duke University Medical Center, Durham NC where he was a faculty member from 1993-2012 before joining the Stanford University faculty in 2012. Interested in innovative learning tools, including novel methods of communicating scientific information, Harrington hosts a regular podcast on theheart.org, The Bob Harrington Show, and can be followed on Twitter @HeartBobH.
Paul Heidenreich, MD
Professor of Medicine (Cardiovascular) and, by courtesy, of Epidemiology and Population Health at the Palo Alto Veterans Affairs Health Care System
Current Research and Scholarly Interests My research interests include
1) The cost-effectiveness of new cardiovascular technologies.
Example: tests to screen asymptomatic patients for left ventricular systolic dysfunction.
2) Interventions to improve the quality of care of patients with heart disease. Examples: include clinical reminders and home monitoring.
3) Outcomes research using existing clinical and administrative datasets.
4) Use of echocardiography to predict prognosis (e.g. diastolic dysfunction).
Professor of Materials Science and Engineering and, by courtesy, of Bioengineering and of Chemical Engineering
Current Research and Scholarly Interests Protein engineering
H. Craig Heller
Lorry I. Lokey/Business Wire Professor
Current Research and Scholarly Interests Neurobiology of sleep, circadian rhythms, regulation of body temperature, mammalian hibernation, and human exercise physiology. Currently applying background in sleep and circadian neurobiology the understanding and correcting the learning disability of Down Syndrome.
Karen G. Hirsch, MD
Associate Professor of Neurology and, by courtesy, of Neurosurgery at the Stanford University Medical Center
Current Research and Scholarly Interests Dr. Karen G. Hirsch cares for critically ill patients with neurologic disorders in the intensive care unit and for patients with cerebrovascular disease in the inpatient stroke unit. Dr. Hirsch's research focuses on novel imaging techniques such as functional brain imaging in patients with cardiac arrest and traumatic brain injury. She also studies methods of non-invasive measurement of cerebral blood flow, oxygenation, and cerebrovascular autoregulation and how these parameters might be targeted to improve outcome in patients with neurologic injury. In the outpatient clinic, she sees patients with head injury, stroke and other neurovascular diseases in addition to patients who have been discharged from the neurological intensive care unit.
Mark Hlatky, MD
Professor of Medicine (Health Services Research), of Medicine (Cardiovascular Medicine) and, by courtesy, of Epidemiology and Population Health
Current Research and Scholarly Interests My main research work is in "outcomes research", especially examining the field of cardiovascular medicine. Particular areas of interest are the integration of economic and quality of life data into randomized clinical trials, evidence-based medicine, decision models, and cost-effectiveness analysis. I am also interested in the application of novel genetic, biomarker, and imaging tests to assess risk and guide clinical management of coronary artery disease.
Ngan F. Huang
Assistant Professor of Cardiothoracic Surgery (Cardiothoracic Surgery Research)
Current Research and Scholarly Interests Dr. Huang's laboratory aims to understand the chemical and mechanical interactions between extracellular matrix (ECM) proteins and pluripotent stem cells that regulate vascular and myogenic differentiation. The fundamental insights of cell-matrix interactions are applied towards stem cell-based therapies with respect to improving cell survival and regenerative capacity, as well as engineered vascularized tissues for therapeutic transplantation.
Professor of Medicine (Cardiovascular Medicine) and, by courtesy, of Epidemiology and Population Health
Current Research and Scholarly Interests We are interested in the link between metabolic disturbances, such as obesity and insulin resistance, and the development of cardiovascular disease. Our research is translational and interdisciplinary, combining population-based studies with molecular biology to reach new insights into the pathophysiology of cardiovascular disease and related conditions, identification of new biomarkers for improved risk prediction, and discovery of novel drug targets.
John P.A. Ioannidis
Professor of Medicine (Stanford Prevention Research), of Epidemiology and Population Health and by courtesy, of Statistics and of Biomedical Data Science
Current Research and Scholarly Interests Meta-research
Clinical and molecular epidemiology
Human genome epidemiology
Reporting of research
Empirical evaluation of bias in research
Statistical methods and modeling
Meta-analysis and large-scale evidence
Prognosis, predictive, personalized, precision medicine and health
Sociology of science
Assistant Professor of Pathology
Current Research and Scholarly Interests We identified a common disorder of aging called clonal hematopoiesis of indeterminate potential (CHIP). CHIP occurs due to certain somatic mutations in blood stem cells and represents a precursor state for blood cancer, but is also associated with increased risk of cardiovascular disease and death. We hope to understand more about the biology and clinical implications of CHIP using human and model system studies.
Instructor, Cardiovascular Institute
Current Research and Scholarly Interests Systems biomedicine, Genetic Risk score, Tumor modelling, Radiomics
Associate Professor of Medicine (Pulmonary and Critical Care Medicine)
Current Research and Scholarly Interests Our research program has several active projects:
1.) Pulmonary Vascular Disease ľ Simvastatin reversed experimental pulmonary hypertension, and is safe for treatment of patients. Blinded clinical trials of efficacy are in progress.
2.) Lung inflammation and regeneration (stem cells)
3.) Lung surfactant rheology and oxidative stress
4.) Gene regulation by RNA binding proteins, NF45 and NF90 through transcriptional and posttranscriptional mechanisms
Michael S. Kapiloff, MD, PhD
Associate Professor (Research) of Ophthalmology and, by courtesy, of Medicine (Cardiovascular Medicine)
Current Research and Scholarly Interests Dr. Michael S. Kapiloff is a faculty member in the Departments of Ophthalmology and Medicine (Cardiovascular Medicine) and a member of the Stanford Cardiovascular Institute. Although Dr. Kapiloff was at one time a Board-Certified General Pediatrician, he is currently involved in full-time basic science and translational research. His laboratory studies the basic molecular mechanisms underlying the response of the retinal ganglion cell and cardiac myocyte to disease. The longstanding interest of his laboratory is the role in intracellular signal transduction of multimolecular complexes organized by scaffold proteins. Recently, his lab has also been involved in the translation of these concepts into new therapies, including the development of new AAV gene therapy biologics for the prevention and treatment of heart failure and for neuroprotection in the eye.
URL to NCBI listing of all published works:
For more information see Dr. Kapiloff's lab website: http://med.stanford.edu/kapilofflab.html