School of Medicine
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Seung K. Kim M.D., Ph.D.
Professor of Developmental Biology and, by courtesy, of Medicine (Endocrinology)
Current Research and Scholarly Interests We study the genetics of pancreatic islet cell differentiation using molecular, embryologic and genetic methods in several model systems, including mice, embryonic stem cells, and Drosophila. Our work suggests that critical factors required for islet development are also needed to maintain essential functions of the mature islet. Our knowledge of genetic and cellular pathways governing islet formation has allowed us to use stem cell lines to produce islet replacements in vitro.
Professor of Developmental Biology, Emeritus
Current Research and Scholarly Interests Mechanisms of Aging in C. elegans and humans.
Rudy J. and Daphne Donohue Munzer Professor in the School of Medicine
Current Research and Scholarly Interests We use mice, stickleback fish, and humans to study the molecular basis of evolution and common diseases. By combining genetics and genomics, we have identified key DNA changes that control bone formation, limb patterning, hair color, brain evolution, and susceptibility to arthritis, schizophrenia, and bipolar disorder. We find that the same genetic mechanisms are often used repeatedly in nature, providing new insights into the origin of key traits in many different species, including ourselves.