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Dr. Michael Fowler is a Professor of Cardiovascular Medicine at Stanford Hospital & Clinics.Dr. Fowler attended the Charing Cross Hospital Medical School, London, England. He has been elected to be a fellow in the Royal College of Physicians. He came to Stanford University on a British Heart Foundation, American Heart Association reciprocal fellowship award. Dr. Fowler was appointed to the faculty in 1982. He is former Medical Director of the Heart Failure Program at Stanford University School of Medicine and Medical Director of the Stanford Cardiomyopathy Center.Dr. Fowler has specialized in the treatment and research related to heart failure for over 35 years. He played an important role in the development of beta blocking drugs to treat heart failure and has also participated in most and the major studies that have led to our current comprehensive treatment for heart failure with drugs and devices. He is an expert in evaluating patients who may benefit from cardiac transplantation or mechanical support therapy.
Adrenergic nervous system; beta-adrenergic function in, heart failure; drugs in heart failure.
Study of the Effect of Sitagliptin on Glucose (Sugar) Metabolism in Patients With Heart Failure
This study will investigate the effects of sitagliptin, a medicine commonly used to treat
type 2 diabetes, on the utilization of glucose by the heart in patients with heart failure
which is not due to heart attacks. We hope to determine whether improving the heart's ability
to use glucose in the blood may help improve the function of the heart as well. If so, this
may suggest that even people who do not have frank diabetes but who do have heart failure may
benefit from using this medication.
This study will also investigate the effect of sitagliptin on the body's use of sugar, and of
the effect of sitagliptin on blood flow to the heart.
Stanford is currently not accepting patients for this trial.
For more information, please contact Ronald Witteles, MD, 650-498-4343.
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