Bio

Honors & Awards


  • Tashia and John Morgridge Endowed Postdoctoral Fellow, Stanford University (2013)
  • Alan M. Krensky Endowed Clinical Fellow, Stanford University (2013)
  • Yale/Stanford Johnson & Johnson Global Scholar, Stanford University (2011)
  • Lucile Packard Children's Hospital Community Grant Recipient, Lucile Packard Children's Hospital (2010)
  • Stanford Pediatric Advocacy Award, Stanford University (2010)
  • Stanford School of Medicine Office of Community Health Seed Grant Recipient, Stanford University (2009)
  • Alpha Omega Alpha, UC Davis School of Medicine (2007)
  • Princeton-in-Africa Fellowship, Princeton University (2005)

Professional Education


  • Fellowship, Stanford University, Pediatric Infectious Diseases (2015)
  • Residency, Stanford University, Pediatrics (2011)
  • MD, University of California Davis School of Medicine, Medicine (2008)
  • BA, Princeton University, Molecular Biology (2003)

Stanford Advisors


Research & Scholarship

Current Research and Scholarly Interests


I am interested in the functional immunity of HIV+ children receiving HAART with respect to the innate immune system as well as T cell activity. It has been shown that HIV+ children on HAART have waning humoral response over time to immunizations despite numerical immune reconstitution. My hypothesis is that HIV+ on HAART demonstrate functional immune abnormalities despite previous antigen exposure and that may require specific vaccine strategies in order to achieve long-term protection.

Publications

Journal Articles


  • Factors Associated with Encephalopathy in Patients with Salmonella enterica Serotype Typhi Bacteremia Presenting to a Diarrheal Hospital in Dhaka, Bangladesh AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE Leung, D. T., Bogetz, J., Itoh, M., Ganapathi, L., Pietroni, M. A., Ryan, E. T., Chisti, M. J. 2012; 86 (4): 698-702

    Abstract

    To characterize clinical correlates of typhoid fever-associated encephalopathy, we performed a retrospective chart review of patients with Salmonella enterica serotype Typhi bacteremia who were hospitalized at the International Centre for Diarrhoeal Disease Research, Bangladesh, from February of 2009 to June of 2011. Of 207 patients bacteremic with Salmonella Typhi who were ? 5 years of age, we identified 43 (21%) patients with encephalopathy. Univariate analysis revealed that patients with encephalopathy more often presented at ages of 10-24 years and had severe dehydration, low oxygen saturation, high respiratory rate, low leukocyte count, low platelet count, and Widal flagellar H agglutinin (TH) titer ? 1:640 compared with typhoid patients without encephalopathy. Multivariate analysis using logistic regression showed that age, dehydration, leukocyte count, and Widal TH titer were independently associated with encephalopathy. Our findings suggest that age, severity of disease, and immune responses are associated with encephalopathy during Salmonella Typhi bacteremia, perhaps reflecting the impact of prominent inflammatory responses.

    View details for DOI 10.4269/ajtmh.2012.11-0750

    View details for Web of Science ID 000302519700023

    View details for PubMedID 22492156

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