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Megan Mayerle
Academic Operations Mgr 1, Microbiology and Immunology - Baxter Labs
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Profiles With Related Publications
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Axel Brunger
Professor of Molecular and Cellular Physiology, of Neurology and Neurological Sciences, of Photon Science and, by courtesy, of Structural Biology
Research Interests
One of my primary goals is to elucidate the molecular mechanisms of synaptic neurotransmitter release by conducting imaging and single-molecule/particle reconstitution experiments, in conjunction with near-atomic resolution structural studies of the synaptic vesicle fusion machinery.
213
Total Publications
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Steven Chu
William R. Kenan Jr. Professor, Professor of Molecular and Cellular Physiology and of Energy Science and Engineering
Research Interests
Synthesis, functionalization and applications of nanoparticle bioprobes for molecular cellular in vivo imaging in biology and biomedicine. Linear and nonlinear difference frequency mixing ultrasound imaging. Lithium metal-sulfur batteries, new approaches to electrochemical splitting of water. CO2 reduction, lithium extraction from salt water
222
Total Publications
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Martha S. Cyert
Dr. Nancy Chang Professor
Research Interests
The Cyert lab is identifying signaling networks for calcineurin, the conserved Ca2+/calmodulin-dependent phosphatase, and target of immunosuppressants FK506 and cyclosporin A, in yeast and mammals. Cell biological investigations of target dephosphorylation reveal calcineurin’s many physiological functions. Roles for short linear peptide motifs, or SLiMs, in substrate recognition, network evolution, and regulation of calcineurin activity are being studied.
70
Total Publications
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Rhiju Das
Professor of Biochemistry
Research Interests
Our lab seeks an agile and predictive understanding of how nucleic acids and proteins code for information processing in living systems. We develop new computational & chemical tools to enable the precise modeling, regulation, and design of RNA and RNA/protein machines.
147
Total Publications
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Sebastian Doniach
Professor of Applied Physics and of Physics, Emeritus
282
Total Publications
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Ron Dror
Cheriton Family Professor and Professor, by courtesy, of Structural Biology and of Molecular & Cellular Physiology
147
Total Publications
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Judith Frydman
Donald Kennedy Chair in the School of Humanities and Sciences and Professor of Genetics
Research Interests
The long term goal of our research is to understand how proteins fold in living cells. My lab uses a multidisciplinary approach to address fundamental questions about molecular chaperones, protein folding and degradation. In addition to basic mechanistic principles, we aim to define how impairment of cellular folding and quality control are linked to disease, including cancer and neurodegenerative diseases and examine whether reengineering chaperone networks can provide therapeutic strategies.
184
Total Publications
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Charles Gawad
Associate Professor of Pediatrics (Hematology/Oncology)
Clinical Focus
Pediatric Hematology-Oncology, Hematologic Malignancies
31
Total Publications
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Rama Reddy Goluguri
Basic Life Research Scientist, Biochemistry
7
Total Publications
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Kip E. Guja, MD PhD
Clinical Assistant Professor, Radiology - Rad/Nuclear Medicine
Clinical Focus
PET Imaging, Theragnostics, Diagnostic Radiology, Pediatric Radiology, Nuclear Radiology
42
Total Publications
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Pehr Harbury
Associate Professor of Biochemistry
Research Interests
Scientific breakthroughs often come on the heels of technological advances; advances that expose hidden truths of nature, and provide tools for engineering the world around us. Examples include the telescope (heliocentrism), the Michelson interferometer (relativity) and recombinant DNA (molecular evolution). Our lab explores innovative experimental approaches to problems in molecular biochemistry, focusing on technologies with the potential for broad impact.
59
Total Publications
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Daniel Herschlag
Professor of Biochemistry and, by courtesy, of Chemical Engineering
Research Interests
Our research is aimed at understanding the chemical and physical behavior underlying biological macromolecules and systems, as these behaviors define the capabilities and limitations of biology. Toward this end we study folding and catalysis by RNA, as well as catalysis by protein enzymes.
340
Total Publications
Publication Topics For This Person
Escherichia coli
Fluorescence Resonance Energy Transfer
Models, Molecular
Molecular Dynamics Simulation
Mutation
Nucleic Acid Conformation
Protein Binding
Protein Conformation
Protein Folding
Protein Subunits
RNA Precursors
RNA Splice Sites
RNA Splicing
RNA, Fungal
RNA, Ribosomal
RNA, Ribosomal, 16S
RNA, Small Nuclear
RNA-Binding Proteins
Retinitis Pigmentosa
Ribonuclease H
Ribonucleoprotein, U1 Small Nuclear
Ribonucleoprotein, U4-U6 Small Nuclear
Ribonucleoprotein, U5 Small Nuclear
Ribosomal Proteins
Ribosome Subunits, Small, Bacterial
Ribosomes
Saccharomyces cerevisiae
Saccharomyces cerevisiae Proteins
Sequence Alignment
Spliceosomes