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Megan Mayerle
Academic Operations Mgr 1, Microbiology and Immunology - Baxter Labs
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Profiles With Related Publications
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Axel Brunger
Professor of Molecular and Cellular Physiology, of Neurology, of Photon Science and, by courtesy, of Structural Biology
Research Interests
One of Axel Brunger's major goals is to decipher the molecular mechanisms of synaptic neurotransmitter release by conducting imaging and single-molecule/particle reconstitution experiments, combined with near-atomic resolution structural studies of the synaptic vesicle fusion machinery.
203
Total Publications
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Gunnar Carlsson
Ann and Bill Swindells Professor, Emeritus
101
Total Publications
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Stanley N. Cohen, MD
Kwoh-Ting Li Professor in the School of Medicine, Professor of Genetics and of Medicine
Research Interests
We study mechanisms that affect the expression and decay of normal and abnormal mRNAs, and also RNA-related mechanisms that regulate microbial antibiotic resistance. A small bioinformatics team within our lab has developed knowledge based systems to aid in investigations of genes.
333
Total Publications
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Martha S. Cyert
Dr. Nancy Chang Professor
Research Interests
The Cyert lab is identifying signaling networks for calcineurin, the conserved Ca2+/calmodulin-dependent phosphatase, and target of immunosuppressants FK506 and cyclosporin A, in yeast and mammals. Cell biological investigations of target dephosphorylation reveal calcineurin’s many physiological functions. Roles for short linear peptide motifs, or SLiMs, in substrate recognition, network evolution, and regulation of calcineurin activity are being studied.
70
Total Publications
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Ron Dror
Professor of Computer Science
130
Total Publications
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Judith Frydman
Donald Kennedy Chair in the School of Humanities and Sciences and Professor of Genetics
Research Interests
The long term goal of our research is to understand how proteins fold in living cells. My lab uses a multidisciplinary approach to address fundamental questions about molecular chaperones, protein folding and degradation. In addition to basic mechanistic principles, we aim to define how impairment of cellular folding and quality control are linked to disease, including cancer and neurodegenerative diseases and examine whether reengineering chaperone networks can provide therapeutic strategies.
165
Total Publications
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Chris Garcia
Younger Family Professor and Professor of Structural Biology
Research Interests
Structural and functional studies of transmembrane receptor interactions with their ligands in systems relevant to human health and disease - primarily in immunity, infection, and neurobiology. We study these problems using protein engineering, structural, biochemical, and combinatorial biology approaches.
344
Total Publications
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Charles Gawad
Associate Professor of Pediatrics (Hematology/Oncology)
Clinical Focus
Pediatric Hematology-Oncology, Hematologic Malignancies
29
Total Publications
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Rama Reddy Goluguri
Postdoctoral Scholar, Biochemistry
6
Total Publications
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Lauren Hagler
Postdoctoral Scholar, Biochemistry
1
Total Publications
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Pehr Harbury
Associate Professor of Biochemistry
Research Interests
Scientific breakthroughs often come on the heels of technological advances; advances that expose hidden truths of nature, and provide tools for engineering the world around us. Examples include the telescope (heliocentrism), the Michelson interferometer (relativity) and recombinant DNA (molecular evolution). Our lab explores innovative experimental approaches to problems in molecular biochemistry, focusing on technologies with the potential for broad impact.
59
Total Publications
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Eline Hendrix
Postdoctoral Scholar, Biochemistry
4
Total Publications
Publication Topics For This Person
Escherichia coli
Fluorescence Resonance Energy Transfer
Models, Molecular
Molecular Dynamics Simulation
Mutation
Nucleic Acid Conformation
Protein Binding
Protein Conformation
Protein Folding
Protein Subunits
RNA Precursors
RNA Splice Sites
RNA Splicing
RNA, Fungal
RNA, Ribosomal
RNA, Ribosomal, 16S
RNA, Small Nuclear
RNA-Binding Proteins
Retinitis Pigmentosa
Ribonuclease H
Ribonucleoprotein, U1 Small Nuclear
Ribonucleoprotein, U4-U6 Small Nuclear
Ribonucleoprotein, U5 Small Nuclear
Ribosomal Proteins
Ribosome Subunits, Small, Bacterial
Ribosomes
Saccharomyces cerevisiae
Saccharomyces cerevisiae Proteins
Sequence Alignment
Spliceosomes