School of Medicine
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Alice C. Fan
Assistant Professor of Medicine (Oncology) at the Stanford University Medical Center
Current Research and Scholarly Interests Dr. Fan is a physician scientist who studies how turning off oncogenes (cancer genes) can cause tumor regression in preclinical and clinical translational studies. Based on her findings, she has initiated clinical trials studying how targeted therapies affect cancer signals in kidney cancer and low grade lymphoma. In the laboratory, she uses new nanotechnology strategies for tumor diagnosis and treatment to define biomarkers for personalized therapy.
Clinical Instructor, Medicine - Vaden Health Center
Bio Diana Farid MD, MPH believes that the arts, education, health and peace are inextricably linked. She holds a BA in Peace and Conflict Studies from Berkeley and completed a Child and Family Health Leadership fellowship at UCLA focused on health communications. She has provided public health education and health care in rural villages in Honduras, promoted peace in the Ukraine and Malaysia, served at an international school in China, worked at the US Agency for International Development in human rights and has had active roles at both Physicians for Social Responsibility and Physicians for Human Rights. She has cared for patients in a wide range of clinic settings including the Los Angeles Free Clinic, where she also precepted internal medicine residents. For two years, she served as "Doctoring" course faculty to first year UCLA medical students. As a physician consultant for "The Media Project? in 2004, she worked with television and film writers and producers to promote adolescent health through entertainment. And in 2009, as a producer with FiddleHeadFern Productions, she completed production of a documentary film, "American Rhythms" (americanrhythmsmovie.com/), which follows a group of 5th grade students at a Los Angeles urban elementary school and their experience of the positive psychological and emotional health effects of a tailored drumming program. Currently, Diana works as a staff physician at the Stanford Vaden student health center, serves as affiliated faculty of Stanford's Medicine and the Muse, Program in Bioethics and Film, writes poetry and is producing a children?s picture book series. She tweets @artelixer.
John W. Farquhar, M.D.
Professor of Medicine and of Health Research and Policy, Emeritus
Current Research and Scholarly Interests Chronic disease prevention, epidemiology of chronic diseases, community-based education for disease prevention, global health, politics and public health.
C. Garrison Fathman
Professor of Medicine (Immunology and Rheumatology), Emeritus
Current Research and Scholarly Interests My lab of molecular and cellular immunology is interested in research in the general field of T cell activation and autoimmunity. We have identified and characterized a gene (GRAIL) that seems to control regulatory T cell (Treg) responsiveness by inhibiting the Treg IL-2 receptor desensitization. We have characterized a gene (Deaf1) that plays a major role in peripheral tolerance in T1D. Using PBC gene expression, we have provisionally identified a signature of risk and progression in T1D.
Postdoctoral Research Fellow, Cardiovascular Medicine
Bio My long-term goal is to investigate the functional genomics of rare and common variants that cause metabolic and cardiovascular comorbidity. In particular, I am interested in the genetics of insulin resistance as major underlying risk factor for cardiometabolic diseases.
After completing my master?s degree, I was attracted by the hypothesis that early onset coronary artery disease (CAD) is a genetic subtype of the common type of CAD. In collaboration with Dr. Arya Mani, an expert in Mendelian forms of CAD (Yale University), and Prof Reza Malekzadeh, a pioneer of cohort studies (Tehran University), and HHMI investigator in Yale University, Dr. Richard Lifton, I contributed to the genetic analysis of families with early onset CAD and metabolic syndrome. We identified DYRK1B as a causative gene (co-first author; N Engl J Med; 2014).
During my PhD thesis, I worked on exome data of Mendelian/monogenic disorders that have been sequenced at Yale Genome center to filter them for rare and pathogenic variants. Also, I used RNA-Seq to sequence the transcriptome of human skeletal muscle biopsies from the carriers and non-carriers of the DYRK1B mutation. I also applied LFQ-MS (label free quantification- tandem mass spectrometry) to address changes in the proteome of DYRK1B mutants in both human muscle biopsies and in vitro models. Through these studies I gained an experimental and conceptual framework for high-throughput data analyses focusing on the networks of metabolic pathways for insulin resistance.
I am enthusiastic to pursue functional genomic characterization of genes found through GWAS of Insulin Resistance with fantastic group of investigators at Stanford medicine.