School of Medicine
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Professor of Medicine (General Medical Disciplines) at the Palo Alto Veterans Administration Health Care System
Current Research and Scholarly Interests My initial research activities involved antiretroviral and novel therapeutic treatments of HIV infection, understanding elements of HIV pathogenesis associated with acute HIV infection and post exposure prevention. My most recent scholarly activities concentrate on working as a team to capitalize on the data stored in electronic medical records, HIV disease modeling and using electronic medical records for outcome research and developing a mentorship program for early career scientists.
Associate Professor of Medicine (Pulmonary and Critical Care Medicine)
Current Research and Scholarly Interests Our research program has several active projects:
1.) Pulmonary Vascular Disease – Simvastatin reversed experimental pulmonary hypertension, and is safe for treatment of patients. Blinded clinical trials of efficacy are in progress.
2.) Lung inflammation and regeneration (stem cells)
3.) Lung surfactant rheology and oxidative stress
4.) Gene regulation by RNA binding proteins, NF45 and NF90 through transcriptional and posttranscriptional mechanisms
Michael S. Kapiloff
Associate Professor (Research) of Ophthalmology and, by courtesy, of Medicine (Cardiovascular Medicine)
Current Research and Scholarly Interests Dr. Michael S. Kapiloff is a faculty member in the Departments of Ophthalmology and Medicine (Cardiovascular Medicine) and a member of the Stanford Cardiovascular Institute. Although Dr. Kapiloff was at one time a Board-Certified General Pediatrician, he is currently involved in full-time basic science and translational research. His laboratory studies the basic molecular mechanisms underlying the response of the retinal ganglion cell and cardiac myocyte to disease. The longstanding interest of his laboratory is the role in intracellular signal transduction of multimolecular complexes organized by scaffold proteins. Recently, his lab has been involved in the translation of these concepts into new therapies, including the development of new AAV gene therapy biologics for the prevention and treatment of heart failure and for neuroprotection in the eye.
URL to NCBI listing of all published works:
Shanthi Kappagoda, MD, MS
Clinical Assistant Professor, Medicine - Infectious Diseases
Current Research and Scholarly Interests Completed a Masters degree in Health Services Research in 2012. Research focused on using network models to develop a clinical research agenda for neglected tropical diseases.