Masatoshi Inoue

Basic Life Research Scientist

Academic Appointments

Basic Life Science Research Associate, Bioengineering

Honors & Awards

The Award for Young Investigator, Japanese Society for Neuroscience (07/01/2020)
Trainee Professional Development Awards, Society for Neuroscience (09/07/2017)
The Award for Young Investigator, Japanese Society for Neurochemistry (7/26/2019)
Selected Hot-Topics research, Society for Neuroscience (8/15/2015)

Professional Education

PhD, University of Tokyo, Neurochemistry (2013)

Patents

Masatoshi Inoue. "United States Patent US20180372762 CALCIUM INDICATOR POLYPEPTIDES AND METHODS OF USE THEREOF", Stanford University, Jun 21, 2017
Masatoshi Inoue. "United States Patent US20170152295 CALCIUM REPORTER GENE", Japan Science and Technology Agency, Jun 14, 2014

All Publications

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Lu Chen

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What distinguishes us humans from other animals is our ability to undergo complex behavior. The synapses are the structural connection between neurons that mediates the communication between neurons, which underlies our various cognitive function. My research program aims to understand the cellular and molecular mechanisms that underlie synapse function during behavior in the developing and mature brain, and how synapse function is altered during mental retardation.

62 Total Publications
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Shaul Druckmann

Assistant Professor of Neurobiology, of Psychiatry and Behavioral Sciences and, by courtesy, of Electrical Engineering
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Our research goal is to understand how dynamics in neuronal circuits relate and constrain the representation of information and computations upon it. We adopt three synergistic strategies: First, we analyze neural circuit population recordings to better understand the relation between neural dynamics and behavior, Second, we theoretically explore the types of dynamics that could be associated with particular network computations. Third, we analyze the structural properties of neural circuits.

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Aaron D. Gitler

Stanford Medicine Basic Science Professor
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We investigate the mechanisms of human neurodegenerative diseases, including Alzheimer disease, Parkinson disease, and ALS. We don't limit ourselves to one model system or experimental approach. We start with yeast, perform genetic and chemical screens, and then move to other model systems (e.g. mammalian tissue culture, mouse, fly) and even work with human patient samples (tissue sections, patient-derived cells, including iPS cells) and next generation sequencing approaches.

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Omer Hazon

Ph.D. Student in Applied Physics, admitted Autumn 2016

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Mark Anthony Hoffman

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John Huguenard

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We are interested in the neuronal mechanisms that underlie synchronous oscillatory activity in the thalamus, cortex and the massively interconnected thalamocortical system. Such oscillations are related to cognitive processes, normal sleep activities and certain forms of epilepsy. Our approach is an analysis of the discrete components (cells, synapses, microcircuits) that make up thalamic and cortical circuits, and reconstitution of components into in silico computational networks.

208 Total Publications
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Isaac Kauvar

Postdoctoral Scholar, Education

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Corey Keller, MD, PhD

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The goal of my lab is to understand the fundamental principles of human brain plasticity and build trans-diagnostic real-time monitoring platforms for personalized neurotherapeutics.

We use an array of neuroscience methods to better understand the basic principles of how to create change in brain circuits. We use this knowledge to develop more effective treatment strategies for depression and other psychiatric disorders.

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Yihe Ma

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Daniel V. Madison

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Our underlying forms of activity-dependent synaptic plasticity such as long-term potentiation and long-term depression, and in particular the function and plasticity of Parvalbumin-containing interneurons in neocortex. In the past few years, we have used a combinatorial approach to comparing physiological and anatomical plasticity-induced changes in synapses using electrode recording and Array Tomography in the same neurons.

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Robert Malenka

Nancy Friend Pritzker Professor of Psychiatry and Behavioral Sciences
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Long-lasting changes in synaptic strength are important for the modification of neural circuits by experience. A major goal of my laboratory is to elucidate the molecular events that trigger various forms of synaptic plasticity and the modifications in synaptic proteins that are responsible for the changes in synaptic efficacy.

275 Total Publications