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Associate Professor (Research) of Biology
Boards, Advisory Committees, Professional Organizations
Board member, The Nueva School (2017 - Present)
Klein, Robert D., Rosenthal, Arnon, Hynes, Mary A.. "United States Patent 6777196 Klein, Robert D., Rosenthal, Arnon, Hynes, Mary A.", Genentech Inc, Aug 17, 2004
Klein, Robert D., Rosenthal, Arnon, Hynes, Mary A.. "United States Patent 6342348 Neurturin receptor", Genentech Inc, Jan 29, 2002
Hynes, Mary A., Ye, Weilan. "United States Patent 6277820 Method of dopaminergic and serotonergic neuron formation from neuroprogenitor cells", Genentech Inc, Aug 21, 2001
Klein, Robert D., Rosenthal, Arnon, Hynes, Mary A.. "United States Patent 6025157 NTNRα, NTNRα extracellular domain (ECD), NTNRα variants, chimeric NTNRα (e.g., NTNRα immunoadhesion), and antibodies which bind thereto (including agonist and neutralizing antibodies) are disclosed. Various uses for these molecules are described.", Genentech Inc, Feb 15, 2000
My Lab Site
BIO 199 (Win, Spr)
Doctoral Dissertation Reader (AC)
Postdoctoral Faculty Sponsor
10 Results / Page
Profiles With Related Publications
James K. Chen
Jauch Professor and Professor of Chemical and Systems Biology, of Developmental Biology and of Chemistry
Our laboratory combines chemistry and developmental biology to investigate the molecular events that regulate embryonic patterning, tissue regeneration, and tumorigenesis. We are currently using genetic and small-molecule approaches to study the molecular mechanisms of Hedgehog signaling, and we are developing chemical technologies to perturb and observe the genetic programs that underlie vertebrate development.
Maria Inmaculada Cobos Sillero
Assistant Professor of Pathology
Anatomic Pathology, Neuropathology
Luis de Lecea
Professor of Psychiatry and Behavioral Sciences (Major Laboratories and Clinical and Translational Neurosciences Incubator)
My lab uses molecular, optogenetic, anatomical and behavioral methods to identify and manipulate the neuronal circuits underlying brain arousal, with particular attention to sleep and wakefulness transitions. We are also interested in the changes that occur in neuronal circuits in conditions of hyperarousal such as stress and drug addiction.
Associate Professor of Neurosurgery and of Neurology
Neural circuits of movement control in health and movement disorders
Edward C. and Amy H. Sewall Professor in the School of Medicine and Professor of Otolaryngology - Head & Neck Surgery (OHNS)
Our research focuses on the inner ear, from its earliest manifestation as one of the cranial placodes until it has developed into a mature and functioning organ. We are interested in how the sensory epithelia of the inner ear that harbor the sensory hair cells develop, how the cells mature, and how these epithelia respond to toxic insults. The overarching goal of this research is to find ways to regenerate lost sensory hair cells in mammals.
Professor of Surgery (Plastic & Reconstructive Surgery)
Dr. Helms' research interests center around regenerative medicine and craniofacial development.
Professor of Neurology and, by courtesy, of Molecular and Cellular Physiology
We are interested in the neuronal mechanisms that underlie synchronous oscillatory activity in the thalamus, cortex and the massively interconnected thalamocortical system. Such oscillations are related to cognitive processes, normal sleep activities and certain forms of epilepsy. Our approach is an analysis of the discrete components (cells, synapses, microcircuits) that make up thalamic and cortical circuits, and reconstitution of components into in silico computational networks.
Associate Professor of Neurosurgery
The lab’s primary research interest is to understand how specific neuronal circuits are established. We use mouse genetics, combinatorial immunochemical labeling and high-resolution laser scanning microscopy to identify, manipulate, and quantitatively analyze synaptic contacts within the complex neuronal milieu of the spinal cord and the enteric nervous system.
Professor (Research) of Psychiatry and Behavioral Sciences
Seung K. Kim M.D., Ph.D.
KM Mulberry Professor, Professor of Developmental Biology, of Medicine (Endocrinology) and, by courtesy, of Pediatrics (Endocrinology)
We study the development of pancreatic islet cells using molecular, embryologic and genetic methods in several model systems, including mice, pigs, human pancreas, embryonic stem cells, and Drosophila. Our work suggests that critical factors required for islet development are also needed to maintain essential functions of the mature islet. These approaches have informed efforts to generate replacement islets from renewable sources for diabetes.
Paul and Mildred Berg Professor
- Lung development and stem cells
- Neural circuits of breathing and speaking
- Lung diseases including lung cancer
- New genetic model organism for biology, behavior, health and conservation
Frank M. Longo, MD, PhD
George E. and Lucy Becker Professor of Medicine and Professor, by courtesy, of Neurosurgery
Alzheimer's Disease, Huntington Disease, Neurology
Clinical interests include Alzheimer's disease and Huntington's disease and the development of effective therapeutics for these disorders. Laboratory interests encompass the elucidation of signaling mechanisms relevant to neurodegenerative disorders and the development of novel small molecule approaches for the treatment of neurodegenerative and other neurological disorders.
Publication Topics For This Person
Gene Expression Regulation, Developmental
Glial Cell Line-Derived Neurotrophic Factor
Molecular Sequence Data
Nerve Growth Factors
Nerve Tissue Proteins
Rats, Inbred Strains
Receptors, Cell Surface