Mark Krasnow

Paul and Mildred Berg Professor

Academic Appointments

Professor, Biochemistry
Member, Bio-X
Member, Cardiovascular Institute
Director, CVI/Vera Moulton Wall Center
Member, Maternal & Child Health Research Institute (MCHRI)
Member, Stanford Cancer Institute
Member, Wu Tsai Neurosciences Institute

Administrative Appointments

Executive Director, Wall Center for Pulmonary Vascular Disease (2010 - Present)
Chair, Dept. of Biochemistry, Stanford University School of Medicine (2006 - 2013)
Associate Chair, Dept. of Biochemistry, Stanford University School of Medicine (2000 - 2006)
Investigator, Howard Hughes Medical Institute (1997 - Present)
Director, Medical Scientist Training Program (1996 - 2002)

Honors & Awards

Member, National Academy of Sciences (2019)
Paul and Mildred Berg Professor, Stanford University (2018)
Member, National Academy of Medicine (2016)
Fellow, American Academy of Arts & Sciences (2009)
Fellow, American Association for the Advancement of Science (1998)
Recipient, Presidential Young Investigator Award (1991-1997)
Recipient, Lucille P. Markey Scholar Award (1987-1993)

Current Research and Scholarly Interests

- Lung development and stem cells
- Neural circuits of breathing and speaking
- Lung diseases including lung cancer
- New genetic model organism for biology, behavior, health and conservation

Stanford Advisees

Med Scholar Project Advisor
Timothy Wu
Doctoral Dissertation Reader (AC)
Chloe Kashiwagi, Gyu Kim, Samuel Kim
Postdoctoral Faculty Sponsor
Xiaoran Guo, Helen Yue Zhang, Yingyue Zhou
Doctoral Dissertation Advisor (AC)
Josh Head, Shahadat Rahman, Timothy Wu, Christine Zhou

Graduate and Fellowship Programs

Biochemistry (Phd Program)
Cancer Biology (Phd Program)
Medicine (Masters Program)
Neonatal-Perinatal Medicine (Fellowship Program)
Pediatric Pulmonology (Fellowship Program)
Pulmonary & Critical Care Medicine (Fellowship Program)
Sleep Medicine (Fellowship Program)

All Publications

Profiles With Related Publications

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Jeffrey Axelrod

Professor of Pathology
Research Interests
Genetic and cell biological analyses of signals controlling cell polarity and morphogenesis. Frizzled signaling and cytoskeletal organization.

95 Total Publications
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Helen M. Blau

Donald E. and Delia B. Baxter Foundation Professor, Director, Baxter Laboratory for Stem Cell Biology and Professor, by courtesy, of Psychiatry and Behavioral Sciences
Research Interests
Prof. Helen Blau's research area is regenerative medicine with a focus on stem cells. Her research on nuclear reprogramming and demonstrating the plasticity of cell fate using cell fusion is well known and her laboratory has also pioneered the design of biomaterials to mimic the in vivo microenvironment and direct stem cell fate. Current findings are leading to more efficient iPS generation, cell based therapies by dedifferentiation a la newts, and discovery of novel molecules and therapies.

302 Total Publications
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Alistair Boettiger

Associate Professor of Developmental Biology
Research Interests
My lab focuses on investigating the role of three-dimensional genome organization in regulating gene expression and in shaping cell fate specification during development. We pursue this with advanced single-molecule imaging and transgenics.

48 Total Publications
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Patrick O. Brown

Professor of Biochemistry, Emeritus
Research Interests
Dr. Brown's research focuses on replacing humanity's most destructive invention - the use of animals as a food technology - by developing a new and better way to produce the world's most delicious, nutritious and affordable meats, fish and dairy foods directly from plants. He is also working on developing and scaling optimal methods for restoring healthy ecosystems and sequestering carbon on the 45% of Earth's surface that have been devastated by animal agriculture.

319 Total Publications
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Howard Y. Chang, MD, PhD

Virginia and D. K. Ludwig Professor of Cancer Research, Professor of Genetics and, by courtesy, of Pathology
Clinical Focus
Cancer > Cutaneous (Dermatologic) Oncology, Dermatology, General Dermatology
Research Interests
Our research is focused on how the activities of hundreds or even thousands of genes (gene parties) are coordinated to achieve biological meaning. We have pioneered methods to predict, dissect, and control large-scale gene regulatory programs; these methods have provided insights into human development, cancer, and aging.

491 Total Publications
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Stanley N. Cohen, MD

Kwoh-Ting Li Professor in the School of Medicine, Professor of Genetics and of Medicine
Research Interests
We study mechanisms that affect the expression and decay of normal and abnormal mRNAs, and also RNA-related mechanisms that regulate microbial antibiotic resistance. A small bioinformatics team within our lab has developed knowledge based systems to aid in investigations of genes.

333 Total Publications
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Gerald Crabtree

David Korn, MD, Professor of Pathology and Professor of Developmental Biology
Research Interests
Chromatin regulation and its roles in human cancer and the development of the nervous system. Engineering new methods for studying and controlling chromatin and epigenetic regulation in living cells.

265 Total Publications
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Andrew Fire

George D. Smith Professor of Molecular and Genetic Medicine and Professor of Pathology and of Genetics
Research Interests
We study natural cellular mechanisms for adapting to genetic change. These include systems activated during normal development and those for detecting and responding to foreign or unwanted genetic activity. Underlying these studies are questions of how a cells can distinguish information as "self" versus "nonself" or "wanted" versus "unwanted".

189 Total Publications
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Margaret T. Fuller

Reed-Hodgson Professor of Human Biology, Katharine Dexter McCormick and Stanley McCormick Memorial Professor and Professor of Genetics and of Obstetrics/Gynecology (Reproductive and Stem Cell Biology)
Research Interests
Regulation of self-renewal, proliferation and differentiation in adult stem cell lineages. Developmental tumor suppressor mechanisms and regulation of the switch from proliferation to differentiation. Cell type specific transcription machinery and regulation of cell differentiation. Developmental regulation of cell cycle progression during male meiosis.

131 Total Publications
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Daria Hekmat-Scafe

Advanced Lecturer

14 Total Publications
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Jill Helms

Professor of Surgery (Plastic & Reconstructive Surgery)
Research Interests
Dr. Helms' research interests center around regenerative medicine and craniofacial development.

213 Total Publications
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Seung K. Kim M.D., Ph.D.

KM Mulberry Professor, Professor of Developmental Biology, of Medicine (Endocrinology) and, by courtesy, of Pediatrics (Endocrinology)
Research Interests
We study the development of pancreatic islet cells using molecular, embryologic and genetic methods in several model systems, including mice, pigs, human pancreas, embryonic stem cells, and Drosophila. Our work suggests that critical factors required for islet development are also needed to maintain essential functions of the mature islet. These approaches have informed efforts to generate replacement islets from renewable sources for diabetes.

89 Total Publications