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Inma Cobos is a physician scientist recently recruited to Stanford in the Department of Pathology. She is a neuropathologist and neuroscientist with expertise in neurodegeneration. Inma received her medical and doctoral degrees from the University of Murcia in Spain and completed post-doctoral training in Developmental Neurobiology at the University of California, San Francisco. She then pursued a clinical residency and fellowship in Anatomic Pathology and Neuropathology at Massachusetts General Hospital, Harvard Medical School. Before joining Stanford, she was an Assistant Professor in the Department of Pathology and Neuropathology at the UCLA David Geffen School of Medicine.Her research program combines her background in diagnostic neuropathology, knowledge of developmental neuroscience, and state-of-the-art cellular and molecular technologies to advance the understanding of Alzheimer’s disease and related dementias. She is currently applying single-cell methods to human brain to dissect the contributions of distinct cell types to Alzheimer’s disease pathogenesis and investigate the mechanisms of tau-mediated neurodegeneration in human brain. Her work is supported by the NIH National Institute of Aging (R01), the Alzheimer’s Association, and BrightFocus. She recently received the Ben Barres Early Career Acceleration Award from the Chan Zuckerberg Initiative (CZI).
Our lab uses cellular and molecular methods, single-cell technology, and quantitative histology to study human neurodegenerative diseases. Current projects include: <br/><br/>- Using single-cell RNA-sequencing to understand selective vulnerability and disease progression in human Alzheimer’s disease brain<br/><br/>- Investigating mechanisms of tau-related neurodegeneration in human brain<br/><br/>- Studying the neocortical and limbic systems in Diffuse Lewy Body Disease (DLBD) at the single cell level